Hexamethyldisiloxane
- CAS No.
- 107-46-0
- Chemical Name:
- Hexamethyldisiloxane
- Synonyms
- HMDSO;HMDO;DISILOXANE;1,1,1,3,3,3-Hexamethyldisiloxane;SILICONE FLUID;Fluka AG;Hexamethylene disiloxane;hexamethyldisiloxane(hmdo);os10;H7310
- CBNumber:
- CB2446352
- Molecular Formula:
- C6H18OSi2
- Molecular Weight:
- 162.38
- MDL Number:
- MFCD00008265
- MOL File:
- 107-46-0.mol
- MSDS File:
- SDS
| Melting point | −59 °C(lit.) |
|---|---|
| Boiling point | 101 °C(lit.) |
| Density | 0.764 g/mL at 20 °C(lit.) |
| vapor density | >1 (vs air) |
| vapor pressure | 20 hPa (20 °C) |
| refractive index |
n |
| Flash point | 33 °F |
| storage temp. | Store below +30°C. |
| solubility | 0.00037g/l insoluble |
| form | liquid |
| Specific Gravity | 0.76 |
| color | Colorless to Almost colorless |
| explosive limit | 0.5-21.8%(V) |
| Water Solubility | insoluble |
| Hydrolytic Sensitivity | 1: no significant reaction with aqueous systems |
| BRN | 1736258 |
| Dielectric constant | 2.2（20℃） |
| Stability | Stable, but moisture sensitive. Highly flammable. Incompatible with strong acids, strong bases, oxidizing agents. |
| InChIKey | UQEAIHBTYFGYIE-UHFFFAOYSA-N |
| LogP | 5.06 at 20℃ |
| CAS DataBase Reference | 107-46-0(CAS DataBase Reference) |
| EWG's Food Scores | 2 |
| FDA UNII | D7M4659BPU |
| NIST Chemistry Reference | Disiloxane, hexamethyl-(107-46-0) |
| EPA Substance Registry System | Hexamethyldisiloxane (107-46-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H410 | |||||||||
| Precautionary statements | P210-P273 | |||||||||
| Hazard Codes | F,N,T | |||||||||
| Risk Statements | 11-50/53-65-51/53-48/23/24/25-36/38-46-45 | |||||||||
| Safety Statements | 16-61-62-45-26-53 | |||||||||
| RIDADR | UN 1993 3/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | JM9237000 | |||||||||
| F | 10 | |||||||||
| Autoignition Temperature | 340 °C | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29310095 | |||||||||
| Toxicity | LD50 orally in Rabbit: > 12160 mg/kg LD50 dermal Rat > 2000 mg/kg | |||||||||
| NFPA 704 |
|
Hexamethyldisiloxane price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.14051 | Hexamethyldisiloxane for synthesis | 107-46-0 | 100mL | $43 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.14051 | Hexamethyldisiloxane for synthesis | 107-46-0 | 500mL | $166 | 2024-03-01 | Buy |
| TCI Chemical | H0091 | Hexamethyldisiloxane >98.0%(GC) | 107-46-0 | 25mL | $17 | 2024-03-01 | Buy |
| TCI Chemical | H0091 | Hexamethyldisiloxane >98.0%(GC) | 107-46-0 | 100mL | $20 | 2024-03-01 | Buy |
| Alfa Aesar | A11848 | Hexamethyldisiloxane, 98+% | 107-46-0 | 100ml | $25.65 | 2024-03-01 | Buy |
Hexamethyldisiloxane Chemical Properties,Uses,Production
Chemical Properties
Hexamethyldisiloxane (HMDS) is a colorless or yellowish transparent liquid with a measured melting point of -68.2°C and a measured boiling point of 100.5°C at 1013 hPa. The measured vapor pressure is 44.51 hPa at 20 oC. The measured water solubility is 0.93 ± 0.63 mg/L at 23 oC. The measured log Kow of HMDS is 5.20 at 20 oC. Estimated log Koc values using EPISuite v 4.10 range from 2.5 (MCI method) to 4.5 (Kow method). As Episuite does not contain fragments for siloxanes for log Koc predictions, these values should be treated with caution. The potential for hydrolysis of the test substance may have influenced the determination of partition coefficient and water solubility.
Physical properties
Hexamethyldisiloxane is a colorless and transparent liquid. It is easily deliquescent, flammable, and has the risk of causing combustion when exposed to high heat, open flame, and strong oxidizing agents. Boiling point 99.5℃. Flash point -1.1℃. Relative density (d2525) 0.7606. refractive index 1.3750. insoluble in water, soluble in many organic solvents.
Uses
The most popular precursor chemical is hexamethyldisiloxane (HMDS) which with the addition of helium and oxygen will produce a silica coating. it is used in a variety of consumer applications and can be used as intermediates in the production of silicone polymers.
Uses
Hexamethyldisiloxane is used as a base fluid in a wide range of personal care products that require fast evaporation and high spreadability. When blended with Dimethicone fluids, It can adjust the residence time of the silicone on the skin. Unlike other volatile fluids, Hexamethyldisiloxane Fluid does not cool the skin as it evaporates. Hexamethyldisiloxane is used as a carrying agent and diluent in the following: skin cream lotions, bath oils, suntan lotions, nail polishes, antiperspirants, deodorants, hair sprays and other beauty and hair care products.
A silicon based compound that can be used to create potentially biocompatible materials.
Used as a monomer in the synthesis of long chain polysiloxane structures.
Used in the methylation of mercury(II) salts.
Uses
Hexamethyldisiloxane can be used as silylating agent for carboxylic acids, and alcohols; used in preparation of aroyl chlorides; precursor for a variety of trimethylsilyl derivatives.Hexamethyldisiloxane has been used as an inexpensive starting material for the preparation of numerous synthetically useful trimethylsilyl derivatives.
Production Methods
Produced via acid hydrolysis of chlorotrimethylsilane and purification by distillation.
Definition
ChEBI: Hexamethyldisiloxane is an organosiloxane consisting of two trimethylsilyl groups covalently bound to a central oxygen.
Preparation
Synthesis of hexamethyldisiloxane by hydrolysis of trimethylsilyl chloride, water and sodium hydroxide.
General Description
Hexamethyldisiloxane (HMDSO), a linear polydisiloxane, is an organosilicon reagent commonly utilized as a source for plasma enhanced chemical vapor deposition (PE-CVD) of thin films of silicon compounds. It is also employed as a substitute to silane in silicon integrated circuit technology. Its dissociative ionization by electron impact has been studied by Fourier transform mass spectrometry. Synthesis of plasma-polymerized HMDSO thin films by atmospheric pressure glow (APG) discharge has been reported. Crystals of HMDSO at 148K are monoclinic. Addition of HMDSO to P4S10, improves its efficiency as thionating agent.
Flammability and Explosibility
Highly flammable
Purification Methods
Fractionally distil through a column packed with glass helices with ca 15 theoretical 20 1.3777. plates. It is highly flammable and is an irritant. [Mills & McKenzie J Am Chem Soc 76 2672 1954, Csakvari et al. J Organometal Chem 107 287 1976, Beilstein 4 IV 4018.]
Hexamethyldisiloxane Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Ningxia Jinhua Chemical Co.,Ltd | 025-52279164 | info@nxjhchem.com | China | 79 | 58 |
| Changde Changlian Chemical Co., Ltd. | +86-25-86736270 +86-15905172087 | brian.he@royal-chem.com | China | 103 | 58 |
| Wuhan Kemi-Works Chemical Co., Ltd. | +86-2785736489 +8618171418573 | sales@kemiworks.com | China | 704 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7377 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Hangzhou Bayee Chemical Co., Ltd. | 0086-571-86990109 | rachelhoo@bayeechem.com | China | 104 | 55 |
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- Apr 22，2022
View Lastest Price from Hexamethyldisiloxane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-19 | Hexamethyldisiloxane
107-46-0
|
US $2.00 / KG | 1KG | ≥99% | 500mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2024-04-19 | Hexamethyldisiloxane(HMDO)
107-46-0
|
US $0.00 / Kg/Drum | 25Kg/Drum | 99% | 200 tons | Ningxia Jinhua Chemical Co.,Ltd | |
 |
2023-12-23 | Hexamethyldisiloxane
107-46-0
|
US $50.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- Hexamethyldisiloxane
107-46-0
- US $2.00 / KG
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- Hexamethyldisiloxane(HMDO)
107-46-0
- US $0.00 / Kg/Drum
- 99%
- Ningxia Jinhua Chemical Co.,Ltd
-
- Hexamethyldisiloxane
107-46-0
- US $50.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd