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Quinine hydrochloride

Quinine hydrochloride structure

CAS No.: 130-89-2

Chemical Name:: Quinine hydrochloride

Synonyms: QUININE HC;QUININE HCL;chinimetten;quininemuriate;quininechloride;Quinine Impurity 11;Quinine hydrochlorid;QUININE HYDROCHLORIDE;Quinine HCL & Sulfate;QUININE HCL USP/EP/BP

CBNumber:: CB2453521

Molecular Formula:: C20H25ClN2O2

Molecular Weight:: 360.88

MDL Number:: MFCD00078498

MOL File:: 130-89-2.mol

Last updated:2024-04-25 13:42:50

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Quinine hydrochloride Properties

Melting point	158-160 C
Density	1.1206 (rough estimate)
refractive index	1.5400 (estimate)
FEMA	2976 \| QUININE HYDROCHLORIDE
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Ethanol (1g/1ml), glycerol(1g/7ml), chloroform(1g/1ml)
form	Solid
color	White
Water Solubility	549.7mg/L(25 ºC)
InChIKey	LBSFSRMTJJPTCW-QJLYHTAINA-N
SMILES	C12C=C(C=CC=1N=CC=C2[C@@H](O)[C@]1([H])C[C@]2([H])CCN1C[C@@H]2C=C)OC.Cl \|&1:10,12,15,21,r\|
LogP	3.496 (est)
Substances Added to Food (formerly EAFUS)	QUININE HYDROCHLORIDE
FDA UNII	7CS0WNO31M
EPA Substance Registry System	Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8.alpha.,9R)- (130-89-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H319
Precautionary statements	P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-24/25
RIDADR	1544
HazardClass	6.1(b)
PackingGroup	III
HS Code	29392000
Toxicity	cat,LDLo,intravenous,80mg/kg (80mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 327, 1927.

Quinine hydrochloride price More Price(12)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	4114	Quininehydrochloride	130-89-2	50	$53	2021-12-16	Buy
TRC	Q694020	QuinineHydrochloride	130-89-2	50mg	$45	2021-12-16	Buy
Usbiological	256384	Quinine hydrochloride	130-89-2	50mg	$267	2021-12-16	Buy
AK Scientific	I951	QuinineHCl	130-89-2	1g	$14	2021-12-16	Buy
American Custom Chemicals Corporation	API0024401	QUININE HYDROCHLORIDE 95.00%	130-89-2	10G	$179.55	2021-12-16	Buy

Product number	Packaging	Price	Buy
4114	50	$53	Buy
Q694020	50mg	$45	Buy
256384	50mg	$267	Buy
I951	1g	$14	Buy
API0024401	10G	$179.55	Buy

Quinine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Quinine hydrochloride is a white, silky, glittering needles; odourless, effloresces when exposed to warm air. Soluble in water, very soluble in ethanol, freely soluble in chloroform, insoluble in ether. Its solutions are neutral or alkaline to litmus. It is an alkaloid derived from the bark of the cinchona tree. Quinine Hydrochloride is used as ingredient of beverages and injection medication.

Uses

Quinine Hydrochloride is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

Definition

Quinine Hydrochloride is the hydrochloride of a natural substance, quinine, obtained from the bark of various species of Cinchona including Cinchona succirubra, Pavon. (red cinchona); Cinchona officinalis, Linn; Cinchona calizaya, Wenddell; Cinchona ledgeriana, Moens. It is a nature-derived bitter flavoring agent for tonic water, among other beverages.

Biological Activity

Quinine hydrochloride is a displays antimalarial and muscle relaxant properties. Stereoisomer of quinidine; closely related to chloroquine.?

Safety Profile

Poison by ingestion, subcutaneous, intravenous, intramuscular, and intraperitoneal routes. Human systemic effects by intravenous route: convulsions or effect on seizure threshold, muscle contraction or spasticity, and nausea or vomiting. Mutation data reported. Used as a local anesthetic. When heated to decomposition it emits very toxic fumes of NO, and HCI. See also QUININE.

Synthesis

Manufacture of quinine by extraction from Cinchona bark and subsequent purification and synthesis to quinine hydrochloride.

target

Adrenergic Receptor

storage

Store at -20°C

Quinine hydrochloride Preparation Products And Raw materials

Raw materials

Cinchona ledgeriana bark Quinine

Preparation Products

Quinine hydrochloride Suppliers

Global( 181)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Nanjing Deda New Material Technology Co., Ltd	+8613223293093	bella@njdeda.com	China	81	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58
Wuhan Ruichi Technology Co., Ltd	+8613545065237	admin@whrchem.com	China	164	58
Sigma Audley	+86-18336680971 +86-18126314766	nova@sh-teruiop.com	China	525	58
Hunan aslsen technology co.,ltd	+8619313031929	aslsd@aslsen.com	China	128	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	2259	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Nanjing Deda New Material Technology Co., Ltd	58
Anhui Ruihan Technology Co., Ltd	58
Wuhan Ruichi Technology Co., Ltd	58
Sigma Audley	58
Hunan aslsen technology co.,ltd	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shanghai Zheyan Biotech Co., Ltd.	58

View Lastest Price from Quinine hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-26	Quinine Hydrochloride 130-89-2	US $15.00-10.00 / kg	1kg	99.5	10 ton per month	Nanjing Deda New Material Technology Co., Ltd
2024-04-25	Quinine hydrochloride 130-89-2	US $5.00 / kg	1kg	99.92%	50000tons	Ouhuang Engineering Materials (Hubei) Co., Ltd
2024-04-22	Quinine HCL 130-89-2	US $10.00 / kg	1kg	99%	20 tons	Hunan aslsen technology co.,ltd

Quinine Hydrochloride
130-89-2
US $15.00-10.00 / kg
99.5
Nanjing Deda New Material Technology Co., Ltd

Quinine hydrochloride
130-89-2
US $5.00 / kg
99.92%
Ouhuang Engineering Materials (Hubei) Co., Ltd

Quinine HCL
130-89-2
US $10.00 / kg
99%
Hunan aslsen technology co.,ltd

Quinine hydrochloride Spectrum

QUININE HCL(130-89-2)¹HNMR QUININE HCL(130-89-2)¹³CNMR QUININE HCL(130-89-2)IR1 QUININE HCL(130-89-2)Raman

130-89-2(Quinine hydrochloride)Related Search:

Quinidine Cinchonidine Quinine sulfate dihydrate Quinine Quinine dihydrochloride

N-BENZYLQUININIUM CHLORIDE Quinine QUININE HCL QUININE HCL / DIHCL / SULFATE Quinine HCl medical grade

QUININE HCL USP(CRM STANDARD) Quinine hydrochloride QUININE HCL NON-KOSHER 6-METHOXYCINCHONINE UREA HYDROCHLORIDE togal

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QUININE HCL QUININE HYDROCHLORIDE QUININE MONOHYDROCHLORIDE 6’-methoxy-,monohydrochloride,(8.alpha.,9R)-Cinchonan-9-ol 6’-methoxy-,monohydrochloride,(8-alpha,9r)-cinchonan-9-o 6’-methoxy-,monohydrochloride,(8alpha,9theta)-cinchonan-9-o chinimetten quininechloride quininemuriate Hydrochloric acid quinine Quinine·hydrochloric acid Quinine HCL & Sulfate Cinchonan-9-ol,6'-Methoxy-, hydrochloride (1:1), (8alpha,9R)- (8alpha,9R)-6'-methoxycinchonan-9-ol monohydrochloride QUININE HYDROCHLORIDE 2 H2O Cinchonan-9-ol, 6-methoxy-, monohydrochloride, (8.alpha.,9R)- Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, (8a,9R)- (9CI) Quinine, monohydrochloride (8CI) (R)-[(4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol:hydrochloride Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8α,9R)- Quinine Hydrochloride HCL QUININE HCL USP/EP/BP (R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride Quinine hydrochlorid (R)-[(2S，4S，5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol hydrochloride QUININE HC Quinine Impurity 11 Cyproconazole Impurity 3 130-89-2 C10H24N2O22H2O C20H24N2O2HCl C20H25N2O2Cl