GAMMA-LINOLENIC ACID METHYL ESTER
- CAS No.
- 16326-32-2
- Chemical Name:
- GAMMA-LINOLENIC ACID METHYL ESTER
- Synonyms
- METHYL GLA;LIGAMO-007;(6Z,9Z,12Z);FAME 18:3N-6;METHYLG-LINOLENATE;Methyl y-linolenate;METHYL-GAMA-LINOLENATE;METHYL GAMMA-LINOLENATE;Caprylic Acid Impurity 72;Methyl γ-linolenate(C18:3)
- CBNumber:
- CB2454755
- Molecular Formula:
- C19H32O2
- Molecular Weight:
- 292.46
- MDL Number:
- MFCD00010455
- MOL File:
- 16326-32-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P280-P305+P351+P338-P337+P313-P403+P235 | |||||||||
| Hazard Codes | F | |||||||||
| Risk Statements | 11 | |||||||||
| Safety Statements | 16 | |||||||||
| RIDADR | UN 1993 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8-10-23 | |||||||||
| NFPA 704 |
|
GAMMA-LINOLENIC ACID METHYL ESTER price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | L6503 | Methyl γ-linolenate ≥99% (GC) | 16326-32-2 | 1g | $644 | 2024-03-01 | Buy |
| Sigma-Aldrich | 00238 | Methyl γ-linolenate solution analytical standard | 16326-32-2 | 1mL | $629 | 2022-05-15 | Buy |
| Cayman Chemical | 10006579 | γ-Linolenic Acid methyl ester ≥98% | 16326-32-2 | 50mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 10006579 | γ-Linolenic Acid methyl ester ≥98% | 16326-32-2 | 100mg | $61 | 2024-03-01 | Buy |
| Sigma-Aldrich | L6503 | Methyl γ-linolenate ≥99% (GC) | 16326-32-2 | 100mg | $119 | 2024-03-01 | Buy |
GAMMA-LINOLENIC ACID METHYL ESTER Chemical Properties,Uses,Production
Description
Polyunsaturated fatty acids (PUFAs) are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet. γ-
Uses
Methyl γ-linolenate may be used as an analytical standard for the determination of aldehydes such as pentanal and hexanal via peroxidation, further analyzed by gas chromatography technique. It may also be used as an analytical reference standard for the quantification of the analyte in serum lipid extract and Arthrospira (Spirulina) platensis using the gas-chromatography technique.
Definition
ChEBI: Methyl gamma-linolenate is a fatty acid methyl ester obtained from the formal condensation of methanol and gamma-linolenic acid. It has a role as a bacterial metabolite, an apoptosis inducer, an antineoplastic agent and an antibacterial agent. It is functionally related to a gamma-linolenic acid.
Biochem/physiol Actions
Methyl γ-linolenate (C18:6,9,12) differs from methyl α-linolenate (C18:9,12,15) in the positions of the double bonds. Methyl γ-linolenate may be used in nutritional studies regarding weight regain and as a possible tumor suppression agent.
in vitro
γ-linolenic acid methyl ester is an esterified version of the free acid which is less water soluble but more amenable for the formulation of gla-containing diets and dietary supplements. gla was identified as an ω-6 fatty acid which could be elongated to arachidonic acid for endogenous eicosanoid synthesis. gla was found to be a weak leukotriene b4 (ltb4) receptor antagonist, which was able to inhibit [3h]-ltb4 binding to porcine neutrophil membranes with a ki of 1 μm [1].
in vivo
in an in-vivo model of ltb4-induced bronchoconstriction, ricinelaidic acid andγ-linolenic acid methyl ester at a 1 mg/kg i.v. dose could result in 46% and 53% inhibition, respectively, indicating that essential fatty acids are ltb4 receptor antagonists, which may account in part for their reported anti-inflammatory activities [1].
References
[1] yagaloff, k. a.,franco, l.,simko, b., et al. essential fatty acids are antagonists of the leukotriene b4 receptor. prostaglandins, leukotrienes and essential fatty acids 52, 293-297 (1995).
GAMMA-LINOLENIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Zhuoer Chemical Co., Ltd | 02120970332; +8613524231522 | sales@zhuoerchem.com | China | 3015 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
View Lastest Price from GAMMA-LINOLENIC ACID METHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | GAMMA-LINOLENIC ACID METHYL ESTER
16326-32-2
|
US $7.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
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- GAMMA-LINOLENIC ACID METHYL ESTER
16326-32-2
- US $7.00 / KG
- 99%
- Career Henan Chemical Co