ChemicalBook >> CAS DataBase List >>(-)-BETA-HYDRASTINE
(-)-BETA-HYDRASTINE
- CAS No.
- 118-08-1
- Chemical Name:
- (-)-BETA-HYDRASTINE
- Synonyms
- HYDRASTINE;l-hydrastine;Hydrastinebase;(-)-Hydrastine;quinolin-5-yl)-;(+/-)-Nor-β(-)--Hydrastine;(-)-B-HYDIASTINE;9S)-β-Hydrastine;(-)-β-Hydrastine
- CBNumber:
- CB2456153
- Molecular Formula:
- C21H21NO6
- Molecular Weight:
- 383.39
- MDL Number:
- MFCD00152561
- MOL File:
- 118-08-1.mol
Last updated:2023-06-08 09:02:51
| Melting point | 132℃ |
|---|---|
| alpha | D20 -50° (c = 0.3 in abs alc) |
| Boiling point | 510.32°C (rough estimate) |
| Density | 1.339±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5614 (estimate) |
| storage temp. | −20°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml |
| form | A crystalline solid |
| pka | 7.8(at 25℃) |
| Water Solubility | 30mg/L(20 ºC) |
| CAS DataBase Reference | 118-08-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 8890V3217X |
(-)-BETA-HYDRASTINE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1313210 | (1R,9S)-(?)-β-Hydrastine United States Pharmacopeia (USP) Reference Standard | 118-08-1 | 10mg | $644 | 2024-03-01 | Buy |
| Cayman Chemical | 22363 | (1R,9S)-(–)-β-Hydrastine ≥98% | 118-08-1 | 5mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 22363 | (1R,9S)-(–)-β-Hydrastine ≥98% | 118-08-1 | 10mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 22363 | (1R,9S)-(–)-β-Hydrastine ≥98% | 118-08-1 | 25mg | $235 | 2024-03-01 | Buy |
| Cayman Chemical | 22363 | (1R,9S)-(–)-β-Hydrastine ≥98% | 118-08-1 | 50mg | $401 | 2024-03-01 | Buy |
(-)-BETA-HYDRASTINE Chemical Properties,Uses,Production
Description
(1R,9S)-(–)-β-Hydrastine is an enantiomer of the alkaloid hydrastine that inhibits dopamine biosynthesis (IC50 = 20.7 μM in PC12 cells) by inhibiting tyrosine hydroxylase activity. It inhibits dopamine release with an IC50 value of 66.5 μM in the presence of high extracellular K+ levels. It also inhibits L-type and caffeine-activated store-operated Ca2+ channels and prevents Ca2+ leakage from intracellular stores.
Uses
(-)-β-Hydrastine is an inhibitor of Dopamine biosynthesis.
Uses
anesthetic (local), antiarrhythmic
Definition
ChEBI: A natural product found in Hydrastis canadensis.
(-)-BETA-HYDRASTINE Preparation Products And Raw materials
Raw materials
Preparation Products
(-)-BETA-HYDRASTINE Suppliers
Global( 75)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9116 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
118-08-1((-)-BETA-HYDRASTINE)Related Search:
HYDRASTINE, (-)-B-(P) (AHP Verified)
HYDRASTINE, (-)-B-(P)
Hydrastine (base and/or unspecified salts)
(1R,9S)-(-)-β-Hydrastine
(3R)-6,7-Dimethoxy-3-[[(1R)-1,2,3,4-tetrahydro-2-methyl-6,7-(methylenedioxy)isoquinoline]-1-yl]isobenzofuran-1(3H)-one
[R,(-)]-6,7-Dimethoxy-3-[[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinoline]-5-yl]isobenzofuran-1(3H)-one
(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
[S,(-)]-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]isobenzofuran-1(3H)-one
6,7-dimethoxy-3-(6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-2-benzofuran-1-one
6,7-dimethoxy-3-(6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one
(1R,9S)-B-hydrastine free base
Hydrastinebase
Hydrastine (10 mg)
l-beta-Hydrastine
l-hydrastine
Phthalide, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-
phthalide,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)iso
quinolin-5-yl)-
HYDRASTINE
HYDRASTINE, (-)-B-
(-)-BETA-HYDRASTINE
(-)-B-HYDIASTINE
(1R,9S)-(-)-BETA-HYDRASTINE
(1R,9S)-BETA-HYDRASTINE
[S-(R*,S*)]-6,7-Dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1(3H)-isobenzofuranone
1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-
6,7-Dimethoxy-3-(6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one
HYDRASTINE (D-beta-)
(-)-Β-HYDRASTINE;(1R;9S)-Β-HYDRASTINE
9S)-β-Hydrastine
N-Desmethyl &beta
(+/-)-Nor-&beta
1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)-
(1R,9S)-(–)-β-Hydrastine
(-)-β-Hydrastine
(-)--Hydrastine
(-)-BETA-HYDRASTINE
Hydrastine (1313210)
(-)-Hydrastine
(S)-6,7-dimethoxy-3-((R)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuran-1(3H)-one
Hydrastine,Inhibitor,inhibit
118-08-1
XYLOCAINE
Aromatics
Heterocycles
Inhibitors
Intermediates & Fine Chemicals
Pharmaceuticals