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17-PHENYL TRINOR PGF2ALPHA-IPR

17-PHENYL TRINOR PGF2ALPHA-IPR Structure
17-PHENYL TRINOR PGF2ALPHA-IPR structure
CAS No.
130209-76-6
Chemical Name:
17-PHENYL TRINOR PGF2ALPHA-IPR
Synonyms
13-trans-Latanoprost;Sparsentan Impurity 17;Bimatoprost isopropyl este;imatoprost isopropyl ester;Bimatoprost isopropyl ester;17-PHENYL TRINOR PGF2ALPHA-IPR;Bimatoprost Acid Isopropyl Ester;17-phenyl trinor PGF2α isopropyl ester;17-phenyl trinor PGF2alpha isopropyl ester;17-phenyl trinor Prostaglandin F2α isopropyl ester
CBNumber:
CB2459437
Molecular Formula:
C26H38O5
Molecular Weight:
430.58
MDL Number:
MFCD00902150
MOL File:
130209-76-6.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:18
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17-PHENYL TRINOR PGF2ALPHA-IPR Properties

Boiling point 573.4±50.0 °C(Predicted)
Density 1.141
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 1 mg/ml
pka 14.25±0.20(Predicted)
FDA UNII 1IFH52MD8T

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS07
Signal word  Danger
Hazard statements  H360-H302+H312+H332
NFPA 704
3
2 0

17-PHENYL TRINOR PGF2ALPHA-IPR price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16824 17-phenyl trinor Prostaglandin F2α isopropyl ester ≥98% 130209-76-6 1mg $73 2024-03-01 Buy
Cayman Chemical 16824 17-phenyl trinor Prostaglandin F2α isopropyl ester ≥98% 130209-76-6 5mg $324 2024-03-01 Buy
Cayman Chemical 16824 17-phenyl trinor Prostaglandin F2α isopropyl ester ≥98% 130209-76-6 10mg $575 2024-03-01 Buy
AHH MT-21382 17-PhenyltrinorPgf2alpha-Ipr 98% 130209-76-6 0.01g $345 2021-12-16 Buy
Product number Packaging Price Buy
16824 1mg $73 Buy
16824 5mg $324 Buy
16824 10mg $575 Buy
MT-21382 0.01g $345 Buy

17-PHENYL TRINOR PGF2ALPHA-IPR Chemical Properties,Uses,Production

Description

17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost. This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. The 17-phenyl trinor PGF2α isopropyl ester derivative was examined for IOP-lowering activity during the development of latanoprost. At the dose of 3 μg/eye in the monkey, 17-phenyl trinor PGF2α isopropyl ester was the most potent analog tested in reducing IOP, lowering the IOP 1.3 mm Hg below the level achieved by latanoprost. However, this derivative was also significantly more irritating to the eye than latanoprost.

Uses

PhDH 100A can be useful in the determination of prostaglandin analogs in cosmetic products by high performance liquid chromatography with tandem mass spectrometry.

Definition

ChEBI: 17-phenyl-trinor-PGF2alpha isopropyl ester is a prostanoid.

17-PHENYL TRINOR PGF2ALPHA-IPR Preparation Products And Raw materials

Raw materials

Preparation Products

17-PHENYL TRINOR PGF2ALPHA-IPR Suppliers

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10326 58
HONG KONG IPURE BIOLOGY CO.,LIMITED 		86 18062405514 18062405514 ada@ipurechemical.com CHINA 3465 58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD. 		+86-029-86333380 18829239519 sales06@tgybio.com China 961 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
Alfa Chemistry 		+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Supplier Advantage
career henan chemical co 		58
BOC Sciences 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Hubei Ipure Biology Co., Ltd 		58
HONG KONG IPURE BIOLOGY CO.,LIMITED 		58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD. 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
sgtlifesciences pvt ltd 		58
Alfa Chemistry 		58

View Lastest Price from 17-PHENYL TRINOR PGF2ALPHA-IPR manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
17-PHENYL TRINOR PGF2ALPHA-IPR pictures 2019-07-06 17-PHENYL TRINOR PGF2ALPHA-IPR
130209-76-6
 US $7.00 / KG 1KG 99% 200KG Career Henan Chemical Co

130209-76-6(17-PHENYL TRINOR PGF2ALPHA-IPR)Related Search:

(Z)-7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-((E)-(S)-3-HYDROXY-5-PHENYL-PENT-1-ENYL)-CYCLOPENTYL]-HEPT-5-ENOIC ACID METHYL ESTER 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA 17-PHENYL TRINOR PGF2ALPHA-IPR
17-phenyl-18,19,20-trinor-prostaglandinf2alpha-1-isopropylester 9ALPHA,11ALPHA,15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER 17-PHENYL TRINOR PGF2ALPHA-IPR 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester Bimatoprost isopropyl ester 17-phenyl trinor Prostaglandin F2α isopropyl ester 17-phenyl trinor PGF2α isopropyl ester isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-5-heptenoic acid propan-2-yl ester propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoate Bimatoprost isopropyl este imatoprost isopropyl ester 17-phenyl trinor PGF2alpha isopropyl ester Bimatoprost Acid Isopropyl Ester 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)- 13-trans-Latanoprost isopropyl phenylhydroxypentene dihydroxycyclopentylheptenate 17-phenyl trinor Prostaglandin F2α isopropyl ester Sparsentan Impurity 17 130209-76-6 C26H38O5