Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>TRIMETHYLSILYL ISOTHIOCYANATE

TRIMETHYLSILYL ISOTHIOCYANATE

TRIMETHYLSILYL ISOTHIOCYANATE Structure
TRIMETHYLSILYL ISOTHIOCYANATE structure
CAS No.
2290-65-5
Chemical Name:
TRIMETHYLSILYL ISOTHIOCYANATE
Synonyms
ISOTHIOCYANATOTRIMETHYLSILANE;TRIMETHYLSILYL ISOTHIOCYANATE;isothiocyanatotrimethyl-silan;Trimethylsilylisothiocyanate,94%;Silane, isothiocyanatotrimethyl-;Trimethylsilyl isothiocyanate,97%;(TriMethylsilyl)isothiocyanate 99%
CBNumber:
CB2460765
Molecular Formula:
C4H9NSSi
Molecular Weight:
131.27
MDL Number:
MFCD00004797
MOL File:
2290-65-5.mol
Last updated:2023-05-09 09:30:36
Request For Quotation

TRIMETHYLSILYL ISOTHIOCYANATE Properties

Melting point −32.8 °C(lit.)
Boiling point 143 °C(lit.)
Density 0.931 g/mL at 25 °C(lit.)
vapor density >1 (vs air)
refractive index n20/D 1.482(lit.)
Flash point 95 °F
storage temp. 2-8°C
form liquid
Specific Gravity 0.931
Water Solubility Reacts with water.
Sensitive Moisture Sensitive
Hydrolytic Sensitivity 8: reacts rapidly with moisture, water, protic solvents
BRN 1745262
InChIKey XLTUPERVRFLGLJ-UHFFFAOYSA-N
CAS DataBase Reference 2290-65-5(CAS DataBase Reference)
FDA UNII JK38S9F7MN
EPA Substance Registry System Isothiocyanatotrimethylsilane (2290-65-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H226-H301+H311+H331-H315-H319-H334-H335
Precautionary statements  P210-P280-P301+P310-P303+P361+P353-P304+P340+P311-P305+P351+P338
Hazard Codes  T
Risk Statements  10-23/24/25-36/37/38-42
Safety Statements  23-26-36/37-45
RIDADR  UN 1992 3/PG 3
WGK Germany  3
F  10-19-21
TSCA  Yes
HazardClass  3
PackingGroup  II
HS Code  29319090
NFPA 704
2
3 0

TRIMETHYLSILYL ISOTHIOCYANATE price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 230766 Trimethylsilyl isothiocyanate 99% 2290-65-5 50g $172.4 2024-03-01 Buy
Sigma-Aldrich 230766 Trimethylsilyl isothiocyanate 99% 2290-65-5 10g $257 2024-03-01 Buy
Alfa Aesar L03277 Trimethylsilyl isothiocyanate 94% 2290-65-5 5g $43.65 2024-03-01 Buy
Alfa Aesar L03277 Trimethylsilyl isothiocyanate 94% 2290-65-5 25g $194 2024-03-01 Buy
Matrix Scientific 153248 Trimethylsilyl isothiocyanate 95% 2290-65-5 10g $222 2021-12-16 Buy
Product number Packaging Price Buy
230766 50g $172.4 Buy
230766 10g $257 Buy
L03277 5g $43.65 Buy
L03277 25g $194 Buy
153248 10g $222 Buy

TRIMETHYLSILYL ISOTHIOCYANATE Chemical Properties,Uses,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

Trimethylsilyl isothiocyanate was used as derivatizing reagent during the synthesis of amino acid thiohydantoins.

Uses

Trimethylsilyl isothiocyanate is used as derivatizing reagent during the synthesis of amino acid thiohydantoins. It participates in ring opening reaction of N-substituted aziridines and cyclohexene oxide.

General Description

Trimethylsilyl isothiocyanate (TMS-ITC) reacts with fullerene-mixed peroxide C60(O)(OOtBu)4 to yield isothiocyanate derivative C60(NCS)(OH)(OOtBu)4. TMS-ITC undergoes condensation with ethyl 2-benzylamino-5-methyl-3-phenylcyclopent-1-enecarboxylate to yield 1-benzyl-5-methyl-7-phenyl-2-thioxo-1,2,3,5,6,7-hexahydrocyclopentapyrimidin-4-one. It participates in ring opening reaction of N-substituted aziridines and cyclohexene oxide.

Purification Methods

The 1H NMR spectrum should have only one peak; if not purify it by repeated fractionation in an all-glass system using a 50cm (4mm internal diameter) column without packing. [Anderson J Am Chem Soc 69 3049 1947, Fehér & Blümcke Chem Ber 90 1934 1957, Neidleim & Hege Synthesis 51 1975, Beilstein 4 III 1861, 4 IV 4011.]

TRIMETHYLSILYL ISOTHIOCYANATE synthesis

18306-29-1
333-20-0
2290-65-5
Synthesis of TRIMETHYLSILYL ISOTHIOCYANATE from Bis(trimethylsilyl)sulfate and Potassium thiocyanate

TRIMETHYLSILYL ISOTHIOCYANATE Preparation Products And Raw materials

Raw materials

Bis(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfide trimethylsilyl isocyanide Bis(trimethylsilyl)sulfate Trimethylsilyl cyanide Potassium thiocyanate
Chlorotrimethylsilane

1of2

Preparation Products

2-Amino-5-methyl-1,3,4-thiadiazole 1-ADAMANTYL ISOTHIOCYANATE PF-06282999 TRIMETHYLSILYL ISOCYANATE ETHYL ISOTHIOCYANATOACETATE
TRIMETHYLSILYL TRIFLUOROACETATE Hexamethyldisiloxane

1of2

TRIMETHYLSILYL ISOTHIOCYANATE Suppliers

Global( 59)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
Shaanxi Didu New Materials Co. Ltd 		+86-89586680 +86-13289823923 1026@dideu.com China 9116 58
PT CHEM GROUP LIMITED 		+86-85511178 +86-85511178 peter68@ptchemgroup.com China 35453 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49999 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32360 55
Shanghai Qiao Chemical Science Co., Ltd 021-58892003 info@qiaochem.com China 5881 65
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Supplier Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Shaanxi Didu New Materials Co. Ltd 		58
PT CHEM GROUP LIMITED 		58
GIHI CHEMICALS CO.,LIMITED 		58
Aladdin Scientific 		58
Mainchem Co., Ltd. 55
Shanghai Qiao Chemical Science Co., Ltd 65
J & K SCIENTIFIC LTD. 76

View Lastest Price from TRIMETHYLSILYL ISOTHIOCYANATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(Trimethylsilyl)isothiocyanate 99% pictures 2021-07-02 (Trimethylsilyl)isothiocyanate 99%
2290-65-5
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

TRIMETHYLSILYL ISOTHIOCYANATE Spectrum

TRIMETHYLSILYL ISOTHIOCYANATE(2290-65-5)FT-IRTRIMETHYLSILYL ISOTHIOCYANATE(2290-65-5)IR

2290-65-5(TRIMETHYLSILYL ISOTHIOCYANATE)Related Search:

4-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER Ethyl isonicotinate Isothiazolinones Benzyl isocyanate Ethoxycarbonyl Isothiocyanate
Benzyl thiocyanate Trimethoxy(pentamethylcyclopentadienyl) titanium(IV) 3-FLUOROPHENYL ISOCYANATE 4-Fluorophenyl isocyanate Ethyl isocyanoacetate
Isopropyl isothiocyanate 2-ETHOXYPHENYL ISOCYANATE Isobutyl isocyanate TRIMETHYLSILYL ISOCYANATE triethyl(3-isocyanatopropyl)silane
TRIMETHYLSILYL ISOTHIOCYANATE isothiocyanic acid

1of4

isothiocyanatotrimethyl-silan Silane, isothiocyanatotrimethyl- TRIMETHYLSILYL ISOTHIOCYANATE Trimethylsilylisothiocyanate,94% Trimethylsilyl isothiocyanate,97% (TriMethylsilyl)isothiocyanate 99% ISOTHIOCYANATOTRIMETHYLSILANE 2290-65-5 C4H9NSSi CH33SiNCS Building Blocks Sulfur Compounds Thiocyanates/Isothiocyanates Organic Building Blocks