ChemicalBook >> CAS DataBase List >>3-Iodophenol

3-Iodophenol

CAS No.
626-02-8
Chemical Name:
3-Iodophenol
Synonyms
3-Jodphenol;m-iodo-pheno;3-iodo-pheno;3-IODOPHENOL;M-IODOPHENOL;3-lodophenol;META-IODOPHENOL;Phenol, m-iodo-;PHENOL, 3-IODO-;3- iodinephenol
CBNumber:
CB2461111
Molecular Formula:
C6H5IO
Molecular Weight:
220.01
MDL Number:
MFCD00002261
MOL File:
626-02-8.mol
MSDS File:
SDS
Last updated:2023-12-24 16:54:11

3-Iodophenol Properties

Melting point 42-44 °C (lit.)
Boiling point 190 °C / 100mmHg
Density 1.8665 (estimate)
Flash point >230 °F
storage temp. 2-8°C
solubility Chloroform, Ethyl Acetate
form Crystalline Powder, Crystals and/or Chunks
pka 9.03(at 25℃)
color Yellow-beige to gray
Water Solubility slightly soluble
Sensitive Light Sensitive
BRN 2039304
InChIKey FXTKWBZFNQHAAO-UHFFFAOYSA-N
CAS DataBase Reference 626-02-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII YU584Z4CZN
NIST Chemistry Reference Phenol, 3-iodo-(626-02-8)
EPA Substance Registry System m-Iodophenol (626-02-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-24/25
RIDADR  UN 3335
WGK Germany  2
RTECS  SL5490000
TSCA  T
HazardClass  IRRITANT
HS Code  29081900
NFPA 704
1
2 0

3-Iodophenol price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I10007 3-Iodophenol 98% 626-02-8 5g $41.6 2024-03-01 Buy
Sigma-Aldrich I10007 3-Iodophenol 98% 626-02-8 25g $111 2024-03-01 Buy
TCI Chemical I0495 3-Iodophenol >98.0%(GC) 626-02-8 10g $91 2024-03-01 Buy
TCI Chemical I0495 3-Iodophenol >98.0%(GC) 626-02-8 25g $178 2024-03-01 Buy
Alfa Aesar A11155 3-Iodophenol, 98% 626-02-8 10g $42.65 2024-03-01 Buy
Product number Packaging Price Buy
I10007 5g $41.6 Buy
I10007 25g $111 Buy
I0495 10g $91 Buy
I0495 25g $178 Buy
A11155 10g $42.65 Buy

3-Iodophenol Chemical Properties,Uses,Production

Chemical Properties

yellow-beige to grey crystalline powder, crystals

Uses

3-Iodophenol is used in esterification, electrophilic aromatic substitution, alkylation, nucleophilic aromatic substitution, Mitsunobu, transition metal-catalyzed cross-coupling, acylation, and oxidation reactions.

Definition

ChEBI: 3-iodophenol is an iodophenol.

Application

3-Iodophenol is used in the synthesis of centrally acting H2 receptor histamine antagonists. Also used in the preparation of various cell-permeable probes for biological assays.

Synthesis

3-Iodophenol Synthesis:
1£?Add potassium tert-butoxide (67.3 mg, 0.60 mmol, 2.0 eq.), oxime (74.5 mg, 0.60 mmol, 2.0 eq.), and 4??-bromoacetophenone (59.7 mg, 0.30 mmol, 1.0 eq.) to an oven-dry screw-cap 8mL reaction vial.
2£?Add anhydrous DMSO (1.5 mL) to the solids a magnetic stir bar.
3£?Close the vial and sparge the reaction mixture with N2 for 15 minutes, seal with parafilm.
4£?Stir the reaction mixture and heat at 100??C in a metal heating block for 16 h.
5£?Dilute the mixture with CH2Cl2 or EtOAc (20 mL), pour into a mixture of water (10mL) and brine (5 mL), acidify with 10% aq HCl (~1 mL).
6£?Collect the organic phase and extract the aqueous phase with CH2Cl2 or EtOAc (3?á20mL).
7£?Combine the organics, dry (MgSO4) and concentrate under reduced pressure.
8£?Purify the crude product to give 3-Iodophenol by column chromatography (30% EtOAc in hexane).
Synthesis_626-02-8

Global( 329)Suppliers
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Henan Fengda Chemical Co., Ltd
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Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58

View Lastest Price from 3-Iodophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Iodophenol pictures 2023-12-24 3-Iodophenol
626-02-8
US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
3-Iodophenol pictures 2023-04-13 3-Iodophenol
626-02-8
US $30.00-10.00 / kg 10kg 99% 100000kg Hebei Guanlang Biotechnology Co,.LTD
3-Iodophenol pictures 2023-03-02 3-Iodophenol
626-02-8
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Guanlang Biotechnology Co., Ltd.
  • 3-Iodophenol pictures
  • 3-Iodophenol
    626-02-8
  • US $100.00-1.00 / KG
  • 99%
  • Henan Fengda Chemical Co., Ltd
  • 3-Iodophenol pictures
  • 3-Iodophenol
    626-02-8
  • US $30.00-10.00 / kg
  • 99%
  • Hebei Guanlang Biotechnology Co,.LTD
  • 3-Iodophenol pictures
  • 3-Iodophenol
    626-02-8
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
M-IODOPHENOL PHENOL, 3-IODO- 3-iodo-pheno 3-Jodphenol m-Hydroxyiodobenzene m-iodo-pheno Phenol, m-iodo- 3-IODOPHENOL META-IODOPHENOL m-Iodophenol 3-Iodophenol 3-Iodophenol,98% 3-Iodophenol,99% Iodine between phenol 3-lodophenol 3-Iodophenol, 99% 25GR 3- iodinephenol 3-IODOPHENOL3-IODOPHENOL3-IODOPHENOL3-IODOPHENOL 3-Iodophenol> 626-02-8 IC6H4OH C6H5OI Building Blocks ALCOHOL Organic Building Blocks Oxygen Compounds Phenols Organic Building Blocks Oxygen Compounds Aromatic Phenols Phenol&Thiophenol&Mercaptan Iodine Compounds Phenols bc0001