3-Iodophenol
- CAS No.
- 626-02-8
- Chemical Name:
- 3-Iodophenol
- Synonyms
- 3-Jodphenol;m-iodo-pheno;3-iodo-pheno;3-IODOPHENOL;M-IODOPHENOL;3-lodophenol;META-IODOPHENOL;Phenol, m-iodo-;PHENOL, 3-IODO-;3- iodinephenol
- CBNumber:
- CB2461111
- Molecular Formula:
- C6H5IO
- Molecular Weight:
- 220.01
- MDL Number:
- MFCD00002261
- MOL File:
- 626-02-8.mol
- MSDS File:
- SDS
Melting point | 42-44 °C (lit.) |
---|---|
Boiling point | 190 °C / 100mmHg |
Density | 1.8665 (estimate) |
Flash point | >230 °F |
storage temp. | 2-8°C |
solubility | Chloroform, Ethyl Acetate |
form | Crystalline Powder, Crystals and/or Chunks |
pka | 9.03(at 25℃) |
color | Yellow-beige to gray |
Water Solubility | slightly soluble |
Sensitive | Light Sensitive |
BRN | 2039304 |
InChIKey | FXTKWBZFNQHAAO-UHFFFAOYSA-N |
CAS DataBase Reference | 626-02-8(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | YU584Z4CZN |
NIST Chemistry Reference | Phenol, 3-iodo-(626-02-8) |
EPA Substance Registry System | m-Iodophenol (626-02-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-37/39-24/25 | |||||||||
RIDADR | UN 3335 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | SL5490000 | |||||||||
TSCA | T | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29081900 | |||||||||
NFPA 704 |
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3-Iodophenol price More Price(35)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | I10007 | 3-Iodophenol 98% | 626-02-8 | 5g | $41.6 | 2024-03-01 | Buy |
Sigma-Aldrich | I10007 | 3-Iodophenol 98% | 626-02-8 | 25g | $111 | 2024-03-01 | Buy |
TCI Chemical | I0495 | 3-Iodophenol >98.0%(GC) | 626-02-8 | 10g | $91 | 2024-03-01 | Buy |
TCI Chemical | I0495 | 3-Iodophenol >98.0%(GC) | 626-02-8 | 25g | $178 | 2024-03-01 | Buy |
Alfa Aesar | A11155 | 3-Iodophenol, 98% | 626-02-8 | 10g | $42.65 | 2024-03-01 | Buy |
3-Iodophenol Chemical Properties,Uses,Production
Chemical Properties
yellow-beige to grey crystalline powder, crystals
Uses
3-Iodophenol is used in esterification, electrophilic aromatic substitution, alkylation, nucleophilic aromatic substitution, Mitsunobu, transition metal-catalyzed cross-coupling, acylation, and oxidation reactions.
Definition
ChEBI: 3-iodophenol is an iodophenol.
Application
3-Iodophenol is used in the synthesis of centrally acting H2 receptor histamine antagonists. Also used in the preparation of various cell-permeable probes for biological assays.
Synthesis
3-Iodophenol Synthesis:
1£?Add potassium tert-butoxide (67.3 mg, 0.60 mmol, 2.0 eq.), oxime (74.5 mg, 0.60 mmol, 2.0 eq.), and 4??-bromoacetophenone (59.7 mg, 0.30 mmol, 1.0 eq.) to an oven-dry screw-cap 8mL reaction vial.
2£?Add anhydrous DMSO (1.5 mL) to the solids a magnetic stir bar.
3£?Close the vial and sparge the reaction mixture with N2 for 15 minutes, seal with parafilm.
4£?Stir the reaction mixture and heat at 100??C in a metal heating block for 16 h.
5£?Dilute the mixture with CH2Cl2 or EtOAc (20 mL), pour into a mixture of water (10mL) and brine (5 mL), acidify with 10% aq HCl (~1 mL).
6£?Collect the organic phase and extract the aqueous phase with CH2Cl2 or EtOAc (3?á20mL).
7£?Combine the organics, dry (MgSO4) and concentrate under reduced pressure.
8£?Purify the crude product to give 3-Iodophenol by column chromatography (30% EtOAc in hexane).
3-Iodophenol Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Fengda Chemical Co., Ltd | +8613613820652 | info@fdachem.com | China | 4685 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 14770 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 722 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29919 | 58 |
Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4242 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
View Lastest Price from 3-Iodophenol manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-12-24 | 3-Iodophenol
626-02-8
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2023-04-13 | 3-Iodophenol
626-02-8
|
US $30.00-10.00 / kg | 10kg | 99% | 100000kg | Hebei Guanlang Biotechnology Co,.LTD | ||
2023-03-02 | 3-Iodophenol
626-02-8
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Guanlang Biotechnology Co., Ltd. |
- 3-Iodophenol
626-02-8
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
- 3-Iodophenol
626-02-8
- US $30.00-10.00 / kg
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
- 3-Iodophenol
626-02-8
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.