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1-NAPHTHOHYDROXAMIC ACID

1-NAPHTHOHYDROXAMIC ACID Structure
1-NAPHTHOHYDROXAMIC ACID structure
CAS No.
6953-61-3
Chemical Name:
1-NAPHTHOHYDROXAMIC ACID
Synonyms
NSC 57457;Naphthohydroxamicacid;a-Naphthohydroxamic acid;1-NAPHTHOHYDROXAMIC ACID;1-NaphthohydroxamicAcid>alpha-naphthohydroxamicacid;1-NAPHTHOHYDROXAMIC ACID 98+%;HDAC Inhibitor XIX, Compound 2;n-hydroxy-1-naphthalenecarboxamid;1-Naphthalenecarbohydroximic acid
CBNumber:
CB2462406
Molecular Formula:
C11H9NO2
Molecular Weight:
187.19
MDL Number:
MFCD00059546
MOL File:
6953-61-3.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:22
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1-NAPHTHOHYDROXAMIC ACID Properties

Melting point 176-178 °C
Density 1.291±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ≥5mg/mL
form White solid
pka 8.91±0.30(Predicted)
color white to tan

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H312-H302-H332
Precautionary statements  P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312
Risk Statements  52
WGK Germany  3
RTECS  QJ1894500
HS Code  2928009090

1-NAPHTHOHYDROXAMIC ACID price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 382177 HDAC Inhibitor XIX, Compound 2 6953-61-3 50mg $110 2023-01-07 Buy
TCI Chemical N0023 1-Naphthohydroxamic Acid >98.0%(T) 6953-61-3 1g $375 2024-03-01 Buy
TRC N369018 1-Naphthohydroxamic Acid 6953-61-3 5mg $55 2021-12-16 Buy
ChemScene CS-0108907 1-Naphthohydroxamic Acid >98.0% 6953-61-3 5mg $65 2021-12-16 Buy
ChemScene CS-0108907 1-Naphthohydroxamic Acid >98.0% 6953-61-3 10mg $120 2021-12-16 Buy
Product number Packaging Price Buy
382177 50mg $110 Buy
N0023 1g $375 Buy
N369018 5mg $55 Buy
CS-0108907 5mg $65 Buy
CS-0108907 10mg $120 Buy

1-NAPHTHOHYDROXAMIC ACID Chemical Properties,Uses,Production

Uses

1-Naphthohydroxamic Acid is a potent HDAC inhibitor with efficacy against HDAC8, HDAC1 and HDAC6.

Biochem/physiol Actions

1-Naphthohydroxamic Acid is a cell-permeable, potent, and selective histone deacetylase 8 (HDAC8) inhibitor. 1-Naphthohydroxamic acid selectively inhibits HDAC8 (IC50 = 14 μM) over class I HDAC1 and class II HDAC6 (IC50 >100 μM). Treatment of cells with 1-Naphthohydroxamic acid does not increase neither global histone H4 nor tubulin acetylation . Also in contrast to the pan-HDAC inhibitors the compound is not reducing total intracellular HDAC activity.

1-NAPHTHOHYDROXAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

1-NAPHTHOHYDROXAMIC ACID Suppliers

Global( 71)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49999 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006608290; 18621169109 market03@meryer.com China 40241 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24539 81
Supplier Advantage
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
GIHI CHEMICALS CO.,LIMITED 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TCI (Shanghai) Development Co., Ltd. 81

1-NAPHTHOHYDROXAMIC ACID Spectrum

1-NAPHTHOHYDROXAMIC ACID(6953-61-3)MS1-NAPHTHOHYDROXAMIC ACID(6953-61-3)1HNMR1-NAPHTHOHYDROXAMIC ACID(6953-61-3)13CNMR1-NAPHTHOHYDROXAMIC ACID(6953-61-3)IR1

6953-61-3(1-NAPHTHOHYDROXAMIC ACID)Related Search:

Pyrazine 2-Naphthohydroxamic acid, O-acetate ester Naftalofos N-HYDROXYNAPHTHALIMIDE SODIUM SALT N-Hydroxy-1,8-naphthalimide
Naphthaloximidodiethyl thiophosphate N-Hydroxynaphthalimide triflate 1-NAPHTHOHYDROXAMIC ACID

1of2

Naphthalene-1-carbohydroximic acid N-Hydroxy-1-naphthalenecarboxamide a-Naphthohydroxamic acid NSC 57457 HDAC Inhibitor XIX, Compound 2 N-HYDROXYNAPHTHALENE-1-CARBOXAMIDE alpha-naphthohydroxamicacid n-hydroxy-1-naphthalenecarboxamid 1-NAPHTHOHYDROXAMIC ACID Naphthohydroxamicacid 1-NAPHTHOHYDROXAMIC ACID 98+% 1-Naphthalenecarbohydroximic acid HDAC Inhibitor XIX, Compound 2 - CAS 6953-61-3 - Calbiochem 1-NaphthohydroxamicAcid> tubulin,anti-proliferation,deacetylate,HDAC8,Inhibitor,1 Naphthohydroxamic acid,hyperacetylated,1Naphthohydroxamic acid,acetylation,inhibit,clone,HDAC,Histone deacetylases,1-Naphthohydroxamic acid 1-Naphthalenecarboxamide, N-hydroxy- 6953-61-3 Hydroxylamines Hydroxylamines (N-Substituted) Hydroxylamines Hydroxylamines (N-Substituted)