BI-409306
- CAS No.
- 1189767-28-9
- Chemical Name:
- BI-409306
- Synonyms
- CS-2883;BI-409306;Osoresnontrine;BI-409306 ，S0039;BI 409306 (BI-409306;BI-409306 (Osoresnontrine);BI 409306;BI-409306;BI409306;Osoresnontrine, 10 mM in DMSO;Osoresnontrine,Inhibitor,BI409306,Phosphodiesterase (PDE),inhibit,BI 409306;6-(pyridin-2-ylmethyl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
- CBNumber:
- CB24668895
- Molecular Formula:
- C16H17N5O2
- Molecular Weight:
- 311.34
- MDL Number:
- MFCD31746892
- MOL File:
- 1189767-28-9.mol
| Product description | Number | Pack Size | Price |
| BI-409306 | 30375 | 1mg | $62 |
| BI-409306 | 30375 | 25mg | $745 |
| BI-409306 | 30375 | 5mg | $194 |
| BI-409306 | 30375 | 10mg | $330 |
| BI-409306 99.97% | CS-0066455 | 5mg | $350 |
| Boiling point | 559.8±60.0 °C(Predicted) |
|---|---|
| Density | 1.48±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO:62.0(Max Conc. mg/mL);199.14(Max Conc. mM) |
| form | A crystalline solid |
| pka | 3.94±0.12(Predicted) |
| color | White to off-white |
| FDA UNII | O9OC34WOAY |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
BI-409306 price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 30375 | BI-409306 | 1189767-28-9 | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 30375 | BI-409306 | 1189767-28-9 | 25mg | $745 | 2024-03-01 | Buy |
| Cayman Chemical | 30375 | BI-409306 | 1189767-28-9 | 5mg | $194 | 2024-03-01 | Buy |
| Cayman Chemical | 30375 | BI-409306 | 1189767-28-9 | 10mg | $330 | 2024-03-01 | Buy |
| ChemScene | CS-0066455 | BI-409306 99.97% | 1189767-28-9 | 5mg | $350 | 2021-12-16 | Buy |
BI-409306 Chemical Properties,Uses,Production
Uses
Osoresnontrine (BI-409306) is a potent and selective PDE9A inhibitor, with an IC50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A (IC50, 1.4 μM), PDE1C (IC50, 1.0 μM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 all > 10 μM); Osoresnontrine can be used in the research of memory enhancement in CNS disorders.
IC 50
PDE9A: 52 nM (IC50); PDE1C: 1 μM (IC50); PDE1A: 1.4 μM (IC50)
References
[1] Cornelia Dorner-Ciossek, et al. BI 409306, a novel phosphodiesterase 9A inhibitor, part I: potency, selectivity and in-vitro functional characterization on synaptic plasticity. International Congress on Schizophrenia Research.
BI-409306 Preparation Products And Raw materials
Raw materials
Preparation Products
BI-409306 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39035 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4764 | 55 | |
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2174 | 55 |
View Lastest Price from BI-409306 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-20 | Osoresnontrine
1189767-28-9
|
US $74.00-198.00 / mg | 99.93% | 10g | TargetMol Chemicals Inc. |
-
- Osoresnontrine
1189767-28-9
- US $74.00-198.00 / mg
- 99.93%
- TargetMol Chemicals Inc.
