3-Hydroxybutyrate Dehydrogenase (3-HBDH)

CAS No.
Chemical Name:
3-Hydroxybutyrate Dehydrogenase (3-HBDH)
Synonyms
3-Hydroxybutyrate Dehydrogenase (3-HBDH)
CBNumber:
CB24668961
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

3-Hydroxybutyrate Dehydrogenase (3-HBDH) Properties

storage temp. 2-8°C
form suspension

3-Hydroxybutyrate Dehydrogenase (3-HBDH) price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 3HBDB-RO 3-Hydroxybutyrate Dehydrogenase (3-HBDH) suspension, ~3?units/mg protein (At 25 °C with 3-hydroxybutyrate as the substrate; standardized with BSA.), grade II 2ML $204 2022-05-15 Buy
Sigma-Aldrich 3HBDB-RO 3-Hydroxybutyrate Dehydrogenase (3-HBDH) suspension, ~3?units/mg protein (At 25 °C with 3-hydroxybutyrate as the substrate; standardized with BSA.), grade II 5ML $391 2022-05-15 Buy
Product number Packaging Price Buy
3HBDB-RO 2ML $204 Buy
3HBDB-RO 5ML $391 Buy

3-Hydroxybutyrate Dehydrogenase (3-HBDH) Chemical Properties,Uses,Production

Uses

3-Hydroxybutyrate Dehydrogenase (3-HBDH) oxidizes selectively (R)-3-hydroxymonocarboxylic acids, or reverse reaction.

General Description

3-Hydroxybutyrate dehydrogenase (3-HBDH) enzyme, obtained from Rhodobacter sphaeroides, is generally used for the quantification of ketone bodies, such as D-3-hydroxybutyrate and acetoacetate.

Biochem/physiol Actions

3-Hydroxybutyrate dehydrogenase (3-HBDH), a mitochondrial enzyme, catalyzes the reversible oxidation of 3-hydroxybutyrate (3HB) to acetoacetate, with NAD as coenzyme. In mammals, acetyl-coA is metabolized, in one of two pathways, to produce acetoacetate and D-3-hydroxybutyrate, which along with acetone are known as ketone bodies. 3-HBDH reversibly reduces this free acetoacetate to D-3--hydroxybutyrate. In patients with diabetic ketoacidosis (DKA), the ratio of 3HB and acetoacetate can be as high as 10:1, as compared to the normal ratio of 1:1. 3-HBDH enzyme can be used to detect the quantity of 3HB in urine, serum, and blood samples.

3-Hydroxybutyrate Dehydrogenase (3-HBDH) Preparation Products And Raw materials

Raw materials

Preparation Products

3-Hydroxybutyrate Dehydrogenase (3-HBDH) Suppliers

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3-Hydroxybutyrate Dehydrogenase (3-HBDH)