3-Hydroxybutyrate Dehydrogenase (3-HBDH)
- CAS No.
- Chemical Name:
- 3-Hydroxybutyrate Dehydrogenase (3-HBDH)
- Synonyms
- 3-Hydroxybutyrate Dehydrogenase (3-HBDH)
- CBNumber:
- CB24668961
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
3-Hydroxybutyrate Dehydrogenase (3-HBDH) price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 3HBDB-RO | 3-Hydroxybutyrate Dehydrogenase (3-HBDH) suspension, ~3?units/mg protein (At 25 °C with 3-hydroxybutyrate as the substrate; standardized with BSA.), grade II | 2ML | $204 | 2022-05-15 | Buy | |
Sigma-Aldrich | 3HBDB-RO | 3-Hydroxybutyrate Dehydrogenase (3-HBDH) suspension, ~3?units/mg protein (At 25 °C with 3-hydroxybutyrate as the substrate; standardized with BSA.), grade II | 5ML | $391 | 2022-05-15 | Buy |
3-Hydroxybutyrate Dehydrogenase (3-HBDH) Chemical Properties,Uses,Production
Uses
3-Hydroxybutyrate Dehydrogenase (3-HBDH) oxidizes selectively (R)-3-hydroxymonocarboxylic acids, or reverse reaction.
General Description
3-Hydroxybutyrate dehydrogenase (3-HBDH) enzyme, obtained from Rhodobacter sphaeroides, is generally used for the quantification of ketone bodies, such as D-3-hydroxybutyrate and acetoacetate.
Biochem/physiol Actions
3-Hydroxybutyrate dehydrogenase (3-HBDH), a mitochondrial enzyme, catalyzes the reversible oxidation of 3-hydroxybutyrate (3HB) to acetoacetate, with NAD as coenzyme. In mammals, acetyl-coA is metabolized, in one of two pathways, to produce acetoacetate and D-3-hydroxybutyrate, which along with acetone are known as ketone bodies. 3-HBDH reversibly reduces this free acetoacetate to D-3--hydroxybutyrate. In patients with diabetic ketoacidosis (DKA), the ratio of 3HB and acetoacetate can be as high as 10:1, as compared to the normal ratio of 1:1. 3-HBDH enzyme can be used to detect the quantity of 3HB in urine, serum, and blood samples.
3-Hydroxybutyrate Dehydrogenase (3-HBDH) Preparation Products And Raw materials
Raw materials
Preparation Products
3-Hydroxybutyrate Dehydrogenase (3-HBDH) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |