Anti-Tau antibody, Mouse monoclonal

CAS No.
Chemical Name:
Anti-Tau antibody, Mouse monoclonal
Synonyms
Anti-Tau antibody, Mouse monoclonal
CBNumber:
CB24669746
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

Anti-Tau antibody, Mouse monoclonal Properties

storage temp. -20°C
form buffered aqueous solution

Anti-Tau antibody, Mouse monoclonal price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T9450 Anti-Tau antibody, Mouse monoclonal clone Tau46, purified from hybridoma cell culture 25μL $104.4 2024-03-01 Buy
Sigma-Aldrich T9450 Anti-Tau antibody, Mouse monoclonal clone Tau46, purified from hybridoma cell culture 100μL $459 2024-03-01 Buy
Sigma-Aldrich T9450 Anti-Tau antibody, Mouse monoclonal clone Tau46, purified from hybridoma cell culture 200μL $657 2024-03-01 Buy
Product number Packaging Price Buy
T9450 25μL $104.4 Buy
T9450 100μL $459 Buy
T9450 200μL $657 Buy

Anti-Tau antibody, Mouse monoclonal Chemical Properties,Uses,Production

Uses

Anti-tau antibody, mouse monoclonal may be used in immunoblotting and immunoprecipitation.

Uses

Anti-Tau antibody, Mouse monoclonal has been used in western blotting.

General Description

Anti-tau antibody, mouse monoclonal (mouse IgG1 isotype) is derived from the tu53 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB /C mice. Tau, also known as microtubule-associated protein tau (MAPT), belongs to microtubule-associated proteins (MAP) family. It consists of six isoforms in the neurons of the adult human brain. MAPT gene is located on the human chromosome at 17q21.31.

Biochem/physiol Actions

Tau loses its microtubule-binding activity and aggregates into paired helical filaments (PHFs) during neurodegenerative disorders. It can undergo modifications such as hyperphosphorylation, nonenzymatic glycosylation and acetylation, which result in the generation of aberrant aggregates such as found in neurofibrillary tangles (NFTs) in Alzheimer′s disease. It is present abundantly in intraneuronal and glial fibrillar lesions formed during neurodegenerative disorders such as tauopathies and Alzheimer′s disease.

Anti-Tau antibody, Mouse monoclonal Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-Tau antibody, Mouse monoclonal Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Anti-Tau antibody, Mouse monoclonal