Human Cathepsin D ELISA
- CAS No.
- Chemical Name:
- Human Cathepsin D ELISA
- Synonyms
- Human Cathepsin D ELISA
- CBNumber:
- CB24670029
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Human Cathepsin D ELISA price More Price(1)
Human Cathepsin D ELISA Chemical Properties,Uses,Production
Uses
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
General Description
This ELISA antibody pair detects human Cathepsin D. Other species not yet determined.
Biochem/physiol Actions
Cathepsin D encoded by CTSD gene, is an aspartyl protease, plays a major role in degradation of intracellular and endocytosed protein, for maintenance of tissue homeostasis and metabolism. Cathepsin D works as an endopeptidase in the acidic environment of lysosomes. Cathepsin D is part of signal transduction and a potential target for various cancer. Increased levels of Cathepsin D is associated with type 2 diabetes. Cathepsin D regulates sphingolipid metabolism and cholesterol trafficking. Genetic variations in Cathepsin D gene is a risk factor for Alzheimer′s disease and neuronal ceroid lipofuscinosis. Cathepsin D is a key marker in atherosclerosis and level of expression is increased in atherosclerotic lesions. Cathepsin D regulates the degradation of advanced glycation end products (AGEs) and impaired activity of cathepsin D results in accumulation of AGEs in photoaged skin. Increased plasma concentration of Cathepsin D causes non-alcoholic steatohepatitis (NASH) leading to hepatic lipid accumulation and inflammation.
Human Cathepsin D ELISA Preparation Products And Raw materials
Raw materials
Preparation Products
Human Cathepsin D ELISA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |