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Tropinone

Tropinone
Tropinone structure
CAS No.
532-24-1
Chemical Name:
Tropinone
Synonyms
Tropanon;Tropinon;ropinone;TROPINONE;Tropanone;NSC 118012;TROPIONONE;3-Tropinone;3-TROPANONE;Tropan-3-on
CBNumber:
CB2470768
Molecular Formula:
C8H13NO
Formula Weight:
139.19
MOL File:
532-24-1.mol

Tropinone Properties

Melting point:
40-44 °C(lit.)
Boiling point:
113 °C25 mm Hg(lit.)
Density 
1.0268 (rough estimate)
refractive index 
1.4598 (estimate)
Flash point:
194 °F
storage temp. 
Inert atmosphere,2-8°C
pka
8.93±0.20(Predicted)
form 
crystalline
color 
brown
PH
8 (18g/l, H2O, 20℃)
BRN 
2329
InChIKey
QQXLDOJGLXJCSE-KNVOCYPGSA-N
CAS DataBase Reference
532-24-1(CAS DataBase Reference)
NIST Chemistry Reference
8-Azabicyclo[3.2.1]octan-3-one, 8-methyl-(532-24-1)
EPA Substance Registry System
8-Azabicyclo[3.2.1]octan-3-one, 8-methyl- (532-24-1)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Hazard statements  H302-H315-H319
Precautionary statements  P280a-P301+P312a-P305+P351+P338-P321-P332+P313-P501a
Hazard Codes  C,Xi
Risk Statements  34-22-36/37/38
Safety Statements  23-24/25-36/37/39-26-22
RIDADR  1544
WGK Germany  3
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29399990
NFPA 704
1
2 0

Tropinone price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T89605 Tropinone 99% 532-24-1 5g $41.1 2021-03-22 Buy
Sigma-Aldrich T89605 Tropinone 99% 532-24-1 10g $75.6 2021-03-22 Buy
TCI Chemical T0626 Tropinone >98.0%(GC)(T) 532-24-1 5g $37 2021-03-22 Buy
TCI Chemical T0626 Tropinone >98.0%(GC)(T) 532-24-1 25g $125 2021-03-22 Buy
Alfa Aesar L02011 Tropinone, 99% 532-24-1 25g $134 2021-03-22 Buy

Tropinone Chemical Properties,Uses,Production

Chemical Properties

Tropinone is a white to light yellow crystal powder, It is an alkaloid and a precursor to a number of additional plant alkaloids. Tropinone is the first intermediate in the biosynthesis of the pharmacologically important tropane alkaloids that possesses the 8-azabicyclo[3.2.1]octane core bicyclic structure that defines this alkaloid class. Chemical synthesis of tropinone was achieved in 1901 but the mechanism of tropinone biosynthesis has remained elusive.

Uses

Tropinone is an oxidative product of Tropane, used to synthesize Morphine and Tropane alkaloids.

Preparation

The first synthesis of tropinone was by Richard Willstätter in 1901. It started from the seemingly related cycloheptanone, but required many steps and had an overall yield of only 0.75%.Willstätter had previously synthesized cocaine from tropinone, in what was the first synthesis and elucidation of the structure of cocaine.
The 1917 synthesis by Robinson is considered a legend in total synthesis due to its simplicity and biomimetic approach. Tropinone is a bicyclic molecule, but the reactants used in its preparation are fairly simple: succinaldehyde, methyl amine and acetone dicarboxylic acid (or even acetone). The synthesis is a good example of a biomimetic reaction or biogenetic-type synthesis because biosynthesis makes use of the same building blocks. It also demonstrates a tandem reaction in a one-pot synthesis. Furthermore the yield of the synthesis was 17% and with subsequent improvements exceeded 90%.

Tropinone Preparation Products And Raw materials

Raw materials

Preparation Products


Tropinone Suppliers

Global( 315)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shijiazhuang Erche Biotechnology Co., Ltd
13343119830 8613343119830
QQ: 956730943 info07@byyq-cn.com CHINA 409 58
HEBEI YINGONG NEW MATERIAL TECHNOLOGY CO.,LTD
+8619933070948
claire@hbyingong.com China 468 58
Hebei Minshang Biological Technology Co. LTD
18132649059 +8618132649059
+8618132649059 monica@hbminshang.cn CHINA 206 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 20914 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8909 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 739 60
Hebei Best Biotechnology Co.,Ltd
+86-13582176207 +86-13582176207
cathy@hbminshang.cn CHINA 304 58
Shanxi Naipu Import and Export Co.,Ltd
+8613734021967
kaia@neputrading.com CHINA 1009 58

Related articles


View Lastest Price from Tropinone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-12-02 Tropinone
532-24-1
US $50.00 / KG 5KG 99% 20tons Xingtai Haoxun Import and Export Trade Co., Ltd.
2021-12-02 Tropinone
532-24-1
US $10.00 / KG 1KG 99.99 10Ton Hebei Miaobian Biotechnology Co., Ltd
2021-12-01 Tropinone
532-24-1
US $30.00 / KG 1KG 99.9% 1000kg/month Shanxi Lianxu New Material Co., LTD

Tropinone Spectrum


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