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TYRPHOSTIN AG 835

TYRPHOSTIN AG 835 structure

CAS No.: 133550-37-5

Chemical Name:: TYRPHOSTIN AG 835

Synonyms: AG 835;TYRPHOSTIN B50;(+)-Enantiomer;TYRPHOSTIN B50(+);TYRPHOSTIN AG 835;TYRPHOSTIN B44, (+) ENANTIOMER;Tyrphostin B44, (+) enantiomer AG835;(S)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide;ALPHA-CYANO-(+)-(S)-N-(ALPHA-PHENETHYL)-(3,4-DIHYDROXY)CINNAMIDE;(+)-(s)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide

CBNumber:: CB2472555

Molecular Formula:: C18H16N2O3

Molecular Weight:: 308.33

MDL Number:: MFCD00209855

MOL File:: 133550-37-5.mol

Last updated:2023-07-12 17:17:45

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TYRPHOSTIN AG 835 Properties

Melting point	146 °C
Boiling point	603.0±55.0 °C(Predicted)
Density	1.299±0.06 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO or ethanol: soluble
form	powder to crystal
pka	8.81±0.10(Predicted)
color	Light yellow to Amber to Dark green

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS08

Signal word

Warning

Hazard statements

H371-H373

Precautionary statements

P501-P260-P270-P264-P308+P311-P405

Safety Statements

22-24/25

WGK Germany

HS Code

2926.90.4801

NFPA 704

	0
2		0

TYRPHOSTIN AG 835 price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	T3540	Tyrphostin AG 835 >98.0%(HPLC)	133550-37-5	25mg	$111	2024-03-01	Buy
TCI Chemical	T3540	Tyrphostin AG 835 >98.0%(HPLC)	133550-37-5	100mg	$304	2024-03-01	Buy
Tocris	0579	TyrphostinB44,(+)enantiomer	133550-37-5	50	$465	2021-12-16	Buy
Tocris	0579	TyrphostinB44,(+)enantiomer	133550-37-5	10	$111	2021-12-16	Buy
TRC	T947985	TyrphostinB44,(+)enantiomer	133550-37-5	5mg	$45	2021-12-16	Buy

Product number	Packaging	Price	Buy
T3540	25mg	$111	Buy
T3540	100mg	$304	Buy
0579	50	$465	Buy
0579	10	$111	Buy
T947985	5mg	$45	Buy

TYRPHOSTIN AG 835 Chemical Properties,Uses,Production

Uses

Tyrphostin B44, (+) enantiomer is an EGFR kinase inhibitor.

Biological Activity

Epidermal growth factor receptor (EGFR) kinase inhibitor (IC 50 = 0.86 μ M). Slightly less active than the (-) enantiomer ((R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ).

TYRPHOSTIN AG 835 Preparation Products And Raw materials

Raw materials

Preparation Products

TYRPHOSTIN AG 835 Suppliers

Global( 53)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24539	81
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9664	60
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28398	80
Shanghai ChuangYan Chemical Technology Co., Ltd.	021-11111111 11111111111	546919421@qq.com	China	2992	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3444	55

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
TCI (Shanghai) Development Co., Ltd.	81
Spectrum Chemical Manufacturing Corp.	60
TOKYO CHEMICAL INDUSTRY CO., LTD.	80
Shanghai ChuangYan Chemical Technology Co., Ltd.	55
EMMX Biotechnology LLC	60
Tianjin Kailiqi Biotechnology Co., Ltd.	55

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TYRPHOSTIN AG 835 TYRPHOSTIN B44

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AG 835 ALPHA-CYANO-(+)-(S)-N-(ALPHA-PHENETHYL)-(3,4-DIHYDROXY)CINNAMIDE (S)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE (+)-(S)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE TYRPHOSTIN B44, (+) ENANTIOMER TYRPHOSTIN AG 835 TYRPHOSTIN B50 TYRPHOSTIN B50(+) (+)-Enantiomer (+)-(s)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide Tyrphostin B50, (+)-(S)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide (2E)-2-Cyano-3-(3,4-Dihydroxyphenyl)-N-[(1S)-1-Phenylethyl]-2-Propenamide Tyrphostin B44, (+) enantiomer AG835 (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-, (2E)- (S)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide non-metastatic tumors,INBL,antitumor,(+)-Tyrphostin B44,Epidermal growth factor receptor,Tyrphostin B50,ErbB-1,Tyrphostin B-44, (+) enantiomer,Inhibitor,Tyrphostin B 50,CALO,cervical carcinoma cell,EGFR,inhibit,Tyrphostin B44, (+) enantiomer,Tyrphostin AG835,HER1,Tyrphostin AG-835,Tyrphostin AG 835,Tyrphostin B-50 (S,E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide 133550-37-5 BioChemical Cell Signaling and Neuroscience Cell Biology Receptor Tyrosine Kinase Inhibitors Kinase/Phosphatase Biology Epidermal Growth Factor Receptor (EGFR) Protein Kinase