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O-PHOSPHORYLETHANOLAMINE

O-PHOSPHORYLETHANOLAMINE
O-PHOSPHORYLETHANOLAMINE structure
CAS No.
1071-23-4
Chemical Name:
O-PHOSPHORYLETHANOLAMINE
Synonyms
Pe 104;NSC 254167;PHOSPHOCOLAMINE;O-PHOSPHOCOLAMINE;Colamine phosphate;Phsophorilcolamine;O-PHOSPHOCHOLAMINE;PHOSPHORYL COLAMINE;PHOSPHOETHANOLAMINE;O-PHOSPHOETHANOLAMINE
CBNumber:
CB2478380
Molecular Formula:
C2H8NO4P
Formula Weight:
141.06
MOL File:
1071-23-4.mol

O-PHOSPHORYLETHANOLAMINE Properties

Melting point:
241-243 °C(lit.)
storage temp. 
−20°C
pka
pK1:5.838(+1);pK2:10.638(0) (25°C)
BRN 
1758916
InChIKey
SUHOOTKUPISOBE-UHFFFAOYSA-N
CAS DataBase Reference
1071-23-4(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T,C
Risk Statements  25-34
Safety Statements  26-36/37/39-45-27
RIDADR  UN 3261 8/PG 2
WGK Germany  3
RTECS  KJ5830000
HazardClass  8
PackingGroup  III
HS Code  29221990
Toxicity LD50 orally in Rabbit: 5820 mg/kg
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P310 Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

O-PHOSPHORYLETHANOLAMINE price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P0503 O-Phosphorylethanolamine 1071-23-4 1g $16.8 2018-11-13 Buy
Sigma-Aldrich P0503 O-Phosphorylethanolamine 1071-23-4 5g $25.5 2018-11-13 Buy
TCI Chemical P0279 O-Phosphorylethanolamine >98.0%(N)(T) 1071-23-4 25g $74 2018-11-22 Buy
TCI Chemical P0279 O-Phosphorylethanolamine >98.0%(N)(T) 1071-23-4 100g $220 2018-11-22 Buy
Sigma-Aldrich P0503 O-Phosphorylethanolamine 1071-23-4 100g $300 2018-11-13 Buy

O-PHOSPHORYLETHANOLAMINE Chemical Properties,Uses,Production

Chemical Properties

O-PHOSPHORYLETHANOLAMINE is white powder

Uses

O-PHOSPHORYLETHANOLAMINEe is used in the synthesis of Sphingomyelin, a type of sphingolipid found in animal cell membrane.

Definition

ChEBI: The ethanolamine mono-ester of phosphoric acid, and a metabolite of phospholipid metabolism. This phosphomonoester shows strong structural similarity to the inhibitory neurotransmitter GABA, and is decreased in post-mortem Alzheimer's disease brain.

Enzyme inhibitor

This phosphorylated metabolite (FW = 141.06 g/mol; CAS 1071-23-4; 10389-08-9 (Ca[1:1] salt); 24027-75-6 (3H-labeled); 37785-54-9 (Zn salt); 34851-96-2 (Mg salt)), also called ethanolamine phosphate, phosphorylethanolamine, and 2-aminoethanol O-phosphate, is a precursor in the biosynthesis of phosphatidylethanolamine. Both the zwitterion and the sodium salt are very soluble in water (20 g/100 mL and 75 g/100 mL at 20°C, respectively): the amino group has a pKa value of 10.20. OPhosphoethanolamine is relatively stable in both acidic and basic conditions. After five hours at 100°C in 1.0 M HCl, 5% has hydrolyzed. Target(s): D-alanyl-D-alanine synthetase, or D-alanine:D-alanine ligase; carnosine synthetase, weakly inhibited; choline-phosphate cytidylyltransferase, weak alternative substrate; glutamate decarboxylase; ornithine decarboxylase; and sphingomyelinase.

Purification Methods

Purification by recrystallisation from aqueous EtOH gives a hydrate (m 140-141o). Its solubility in H2O is 17% and 0.003% in MeOH or EtOH at 22o. [F.lisch & .sterberg J Biol Chem 234 2298 1959, Baer & Staucer Can J Chem 34 434 1956, Christensen J Biol Chem 135 399 1940.] It is a potent inhibitor of ornithine decarboxylase [Gilad & Gilad Biochem Biophys Res Commun 122 277 1984]. [Beilstein 4 IV 1415.]

O-PHOSPHORYLETHANOLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products


O-PHOSPHORYLETHANOLAMINE Suppliers

Global( 94)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
GIHI CHEMICALS CO.,LIMITED
08657186217390
sales@gihichemicals.com CHINA 308 58
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21935 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20676 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32452 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 25796 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23958 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8266 58
Hubei xin bonus chemical co. LTD
13657299721
zhangyuzhu@xhlchem.com CHINA 17424 58
Shanghai Changyan Chem & Tech Co., Ltd. +86 (21) 2024-2659
+86 (21) 2024-2659 order@changyanchem.com China 5001 55

View Lastest Price from O-PHOSPHORYLETHANOLAMINE manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-09 O-PHOSPHORYLETHANOLAMINE
1071-23-4
US $1.00 / KG 1KG 99% Customized career henan chemical co
2019-01-31 O-Phosphorylethanolamine
1071-23-4
US $1.00-10.00 / KG 1Kgs/塑料桶 99% 1ton GIHI CHEMICALS CO.,LIMITED

O-PHOSPHORYLETHANOLAMINE Spectrum


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