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Deruxtecan

Deruxtecan Structure
Deruxtecan structure
CAS No.
1599440-13-7
Chemical Name:
Deruxtecan
Synonyms
Deruxtecan;MC-GGFG-Exetecan;Deruxtecan analog;Deruxtecan（DX-8951）;Ibandronate Impurity 32;MC-GGFG-Exetecan Deruxtecan analog;Drug-Linker Conjugates for ADC,Inhibitor,inhibit,Deruxtecan;Glycinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[[2-[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]amino]-2-oxoethoxy]methyl]-;N-[(S)-10-Benzyl-1-[[(1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-1,2,3,9,10,12,13,15-octahydrobenzo[de]pyrano[3’,4’:6,7]indolizino[1,2-b]quinolin-1-yl]amino]-1,6,9,12,15-pentaoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-yl]-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide;N-((S)-10-Benzyl-1-(((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)amino)-1,6,9,12,15-pentaoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-yl)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide
CBNumber:
CB24796642
Molecular Formula:
C52H56FN9O13
Molecular Weight:
1034.05
MDL Number:
MFCD31657445
MOL File:
1599440-13-7.mol
Last updated:2023-09-28 13:28:25
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Deruxtecan Properties

Boiling point 1491.1±65.0 °C(Predicted)
Density 1.48±0.1 g/cm3(Predicted)
solubility DMSO:67.5(Max Conc. mg/mL);65.28(Max Conc. mM)
pka 11.18±0.40(Predicted)
FDA UNII 5SEB972CO4

Deruxtecan price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0045125 Deruxtecan 99.43% 1599440-13-7 1mg $750 2021-12-16 Buy
ChemScene CS-0045125 Deruxtecan 99.43% 1599440-13-7 5mg $1500 2021-12-16 Buy
ChemScene CS-0045125 Deruxtecan 99.43% 1599440-13-7 10mg $1950 2021-12-16 Buy
Product number Packaging Price Buy
CS-0045125 1mg $750 Buy
CS-0045125 5mg $1500 Buy
CS-0045125 10mg $1950 Buy

Deruxtecan Chemical Properties,Uses,Production

Uses

Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

Mechanism of action

Deruxtecan is attached to the antibody by a peptide linker. After trastuzumab deruxtecan binds to HER2 found on malignant cells, it is internalized and linker cleavage occurs through the actions of lysosomal enzymes. After it is released through cleavage, DXd causes targeted DNA damage and apoptosis in cancer cells, due to the ability to cross cell membranes.

Deruxtecan Preparation Products And Raw materials

Raw materials

Preparation Products

Deruxtecan Suppliers

Global( 97)Suppliers
Supplier Tel Email Country ProdList Advantage
Xilinglab Co., Ltd.
+8618381337976 bd@xilinglab.com China 86 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 6992 58
Chengdu Pukang Biotechnology Co., Ltd 		028-82550498 export@pu-kang.com CHINA 210 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9702 58
Shenzhen Shengda Pharma Limited 		755-85269922 +8613424394241 sales@shengdapharm.com CHINA 310 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Supplier Advantage
Xilinglab Co., Ltd.
58
ATK CHEMICAL COMPANY LIMITED 		60
Jinan Carbotang Biotech Co.,Ltd. 		58
Chengdu Pukang Biotechnology Co., Ltd 		58
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Finetech Industry Limited 		58
Shenzhen Shengda Pharma Limited 		58
Zhejiang J&C Biological Technology Co.,Limited 		58

View Lastest Price from Deruxtecan manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Deruxtecan pictures 2022-10-14 Deruxtecan
1599440-13-7
 US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
Deruxtecan pictures 2022-03-07 Deruxtecan
1599440-13-7
 US $4666.00 / mg/bottle 100mg/bottle 99% 10kg Shenzhen Shengda Pharma Limited
  • Deruxtecan pictures
  • Deruxtecan
    1599440-13-7
  • US $0.00-0.00 / KG
  • 98%
  • Henan Aochuang Chemical Co.,Ltd.
  • Deruxtecan pictures
  • Deruxtecan
    1599440-13-7
  • US $4666.00 / mg/bottle
  • 99%
  • Shenzhen Shengda Pharma Limited

1599440-13-7(Deruxtecan)Related Search:

Deruxtecan
Deruxtecan analog Glycinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[[2-[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]amino]-2-oxoethoxy]methyl]- MC-GGFG-Exetecan Deruxtecan Deruxtecan（DX-8951） N-((S)-10-Benzyl-1-(((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)amino)-1,6,9,12,15-pentaoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-yl)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide Drug-Linker Conjugates for ADC,Inhibitor,inhibit,Deruxtecan Ibandronate Impurity 32 N-[(S)-10-Benzyl-1-[[(1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-1,2,3,9,10,12,13,15-octahydrobenzo[de]pyrano[3’,4’:6,7]indolizino[1,2-b]quinolin-1-yl]amino]-1,6,9,12,15-pentaoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-yl]-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide MC-GGFG-Exetecan Deruxtecan analog 1599440-13-7 C52H56FN9O13 Pharmaceutical API ADC