Fas/FasL Antagonist, Kp7-6 - Calbiochem
- CAS No.
- Chemical Name:
- Fas/FasL Antagonist, Kp7-6 - Calbiochem
- Synonyms
- Fas/FasL Antagonist, Kp7-6 - Calbiochem
- CBNumber:
- CB24817169
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Fas/FasL Antagonist, Kp7-6 - Calbiochem price More Price(1)
Fas/FasL Antagonist, Kp7-6 - Calbiochem Chemical Properties,Uses,Production
General Description
An exocyclic cysteine-knot peptide that specifically antagonizes Fas/FasL-mediated cellular apoptotic signals (58% reduction of FasL-induced apoptosis in Jurkat cells at 1 mg/ml). Binds to FasL (Cat. Nos. PF033 and PF092) and Fas (CD95/APO-1) with comparable affinity (Kd = 11.2 & 13.2 μM, respectively), resulting in disabled receptor ensembles and altered signaling. Shown to prevent Con A (Cat. No. 234567)-induced liver injury in a murine hepatitis model in vivo. Does not bind to TNF-α or TNFR.
Biochem/physiol Actions
Product does not compete with ATP.
Fas/FasL Antagonist, Kp7-6 - Calbiochem Preparation Products And Raw materials
Raw materials
Preparation Products
Fas/FasL Antagonist, Kp7-6 - Calbiochem Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
Fas/FasL Antagonist, Kp7-6 - Calbiochem