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Oxaceprol

Oxaceprol
Oxaceprol structure
CAS No.
33996-33-7
Chemical Name:
Oxaceprol
Synonyms
CO-61;AHP-200;Jonctum;Ac-L-Hyp;AC-HYP-OH;OXACEPROL;N-AC-L-HYP;Ac-L-Hyp-OH;trans-l-prolin;Hyp4001Ac-Hyp-Oh
CBNumber:
CB2482503
Molecular Formula:
C7H11NO4
Formula Weight:
173.17
MOL File:
33996-33-7.mol

Oxaceprol Properties

Melting point:
132-133 °C (dec.)(lit.)
Boiling point:
303.8°C (rough estimate)
alpha 
-119 º (c=4 in H2O)
Density 
1.3346 (rough estimate)
refractive index 
1.4490 (estimate)
storage temp. 
Sealed in dry,2-8°C
form 
Crystalline Powder
pka
3.48±0.40(Predicted)
color 
White
optical activity
[α]20/D 119°, c = 4 in H2O
Merck 
14,6903
BRN 
84043
InChIKey
BAPRUDZDYCKSOQ-RITPCOANSA-N
CAS DataBase Reference
33996-33-7(CAS DataBase Reference)
FDA UNII
Q0XV76B96L
ATC code
D11AX09,M01AX24
EPA Substance Registry System
L-Proline, 1-acetyl-4-hydroxy-, (4R)- (33996-33-7)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H315-H335-H318
Precautionary statements  P261-P280a-P304+P340-P405-P501a-P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  41
Safety Statements  26-36
WGK Germany  3
10
TSCA  Yes
HS Code  29339900

Oxaceprol price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 441562 trans-1-Acetyl-4-hydroxy-L-proline ≥98% 33996-33-7 10g $141 2021-03-22 Buy
Alfa Aesar B23767 N-Acetyl-trans-4-hydroxy-L-proline, 99% 33996-33-7 2g $39.4 2021-03-22 Buy
Alfa Aesar B23767 N-Acetyl-trans-4-hydroxy-L-proline, 99% 33996-33-7 10g $121 2021-03-22 Buy
Alfa Aesar B23767 N-Acetyl-trans-4-hydroxy-L-proline 99% 33996-33-7 5g $71.6 2021-03-22 Buy
Alfa Aesar B23767 N-Acetyl-trans-4-hydroxy-L-proline, 99% 33996-33-7 50g $428 2020-06-24 Buy

Oxaceprol Chemical Properties,Uses,Production

Chemical Properties

White powder

Originator

Jonctum,Merrell,France,1970

Manufacturing Process

16.7 g (0.127 mol) of L-hydroxyproline are dissolved in 400 ml of pure boiling acetic acid. With vigorous boiling and agitation, a mixture of 13.7 ml (0.154 mol) of rectified acetic anhydride and 250 ml of pure acetic acid is added during 25 minutes. Without discontinuing the stirring, contents of the flask are cooled by simply causing fresh air to circulate externally round the flask until the temperature of the mixture is reduced to about 35°C. The acetic acid is removed by using a rotary evaporator without exceeding 35°C under a vacuum of about 15 mm Hg. After one hour, 20 ml of anhydrous toluene are added, then 10 ml of anhydrous acetone; the mixture is homogenized and concentrated again as above during 30 minutes. Then 25 ml of acetone are added again, and subsequently 20 ml of toluene, the product being concentrated again; gradually the solution is converted into an amber-colored crystallized paste. Finally, 30 ml of acetone are added to the residue, and stirring is carried out until the oily fraction surrounding the crystals is dissolved. The product is then cooled in an ice chamber, centrifuged, washed with anhydrous acetone and eventually dried, After recrystallization from acetone, crystals are obtained, melting point 132°C.

Therapeutic Function

Antirheumatic

Oxaceprol Preparation Products And Raw materials

Raw materials

Preparation Products


Oxaceprol Suppliers

Global( 188)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 20907 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29954 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 19969 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5930 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
BOC Sciences
1-631-485-4226
1-631-614-7828 inquiry@bocsci.com United States 19752 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58

View Lastest Price from Oxaceprol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-09-29 N-Acetyl-L-hydroxyproline
33996-33-7
US $0.00 / Kg/Drum 1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
2019-07-06 Oxaceprol
33996-33-7
US $367.60-136.80 / KG 1KG 99% 100KG career henan chemical co

Oxaceprol Spectrum


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