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3-TRIMETHYLSILYL-2-PROPYN-1-OL

3-TRIMETHYLSILYL-2-PROPYN-1-OL structure

CAS No.: 5272-36-6

Chemical Name:: 3-TRIMETHYLSILYL-2-PROPYN-1-OL

Synonyms: 3-(triMethylsilyl)prop-2-yn-1-ol;3-(TRIMETHYLSILYL)PROPARGYL ALCOHOL;3-TRIMETHYLSILANYL-PROP-2-YN-1-OL;3-Trimethylsilyl-2-propyn-1-ol,99%;2-Propyn-1-ol, 3-(trimethylsilyl)-;3-(Trimethylsilyl)propargyl alcohol 99%;TIMTEC-BB SBB009061;3-Trimethylsilylpropargyl;3-TRIMETHYLSILYL-2-PROPYN-1-OL;TRIMETHYLSILYLPROPARGYL ALCOHOL

CBNumber:: CB2482992

Molecular Formula:: C6H12OSi

Molecular Weight:: 128.24

MDL Number:: MFCD00002913

MOL File:: 5272-36-6.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

Request For Quotation

3-TRIMETHYLSILYL-2-PROPYN-1-OL Properties

Melting point	63.5-65.0 °C
Boiling point	76 °C11 mm Hg(lit.)
Density	0.865 g/mL at 25 °C(lit.)
refractive index	n20/D 1.451(lit.)
Flash point	152 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Benzene (Sparingly)
pka	13.71±0.10(Predicted)
form	Liquid
color	Clear yellow
Specific Gravity	0.865
Water Solubility	Not miscible with water.
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	4: no reaction with water under neutral conditions
BRN	1902505
InChIKey	ZVGCJDPEKKEYES-UHFFFAOYSA-N
CAS DataBase Reference	5272-36-6(CAS DataBase Reference)
NIST Chemistry Reference	3-Trimethylsilylpropargyl alcohol(5272-36-6)
EPA Substance Registry System	2-Propyn-1-ol, 3-(trimethylsilyl)- (5272-36-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Warning

Hazard statements

H227-H301-H315-H319-H335

Precautionary statements

P261-P280h-P305+P351+P338-P309-P310

Hazard Codes

Risk Statements

36/37/38

Safety Statements

23-24/25-37/39-26

RIDADR

2810

WGK Germany

8-10

TSCA

Yes

HazardClass

6.1

PackingGroup

III

HS Code

29319090

NFPA 704

	2
2		0

3-TRIMETHYLSILYL-2-PROPYN-1-OL price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	318558	3-(Trimethylsilyl)propargyl alcohol 99%	5272-36-6	5g	$64.9	2024-03-01	Buy
TCI Chemical	T1500	3-Trimethylsilyl-2-propyn-1-ol >95.0%(GC)	5272-36-6	5mL	$85	2024-03-01	Buy
Alfa Aesar	L09649	3-(Trimethylsilyl)propargyl alcohol, 98+%	5272-36-6	1g	$35.65	2024-03-01	Buy
Alfa Aesar	L09649	3-(Trimethylsilyl)propargyl alcohol, 98+%	5272-36-6	5g	$111	2024-03-01	Buy
Alfa Aesar	L09649	3-(Trimethylsilyl)propargyl alcohol, 98+%	5272-36-6	25g	$358.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
318558	5g	$64.9	Buy
T1500	5mL	$85	Buy
L09649	1g	$35.65	Buy
L09649	5g	$111	Buy
L09649	25g	$358.65	Buy

3-TRIMETHYLSILYL-2-PROPYN-1-OL Chemical Properties,Uses,Production

Chemical Properties

clear yellow liquid

Uses

Trimethylsilylpropargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.

3-TRIMETHYLSILYL-2-PROPYN-1-OL synthesis

Synthesis of 3-TRIMETHYLSILYL-2-PROPYN-1-OL from Tetrahydro-2-[[3-(trimethylsilyl)-2-propyn-1-yl]oxy]-2H-Pyran

3-TRIMETHYLSILYL-2-PROPYN-1-OL Preparation Products And Raw materials

Raw materials

Bis[tris(trimethylsilyl)silyl]zinc Tetrahydro-2-[[3-(trimethylsilyl)-2-propyn-1-yl]oxy]-2H-Pyran PROPARGYLOXYTRIMETHYLSILANE TETRAHYDRO-2-(2-PROPYNYLOXY)-2H-PYRAN 1-trimethylsilyloxy-3-trimethylsilylprop-2-yne

PHENYLETHYNYLMAGNESIUM BROMIDE 1-PHENYL-2-(TRIMETHYLSILYL)ACETYLENE Bromoethane Dichlorodimethylsilane Propargyl alcohol

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Preparation Products

3-BROMO-1-(TRIMETHYLSILYL)-1-PROPYNE 1-Trimethylsilyl-1-butyne 3-TRIMETHYLSILYLPROPYNAL 3-Iodo-1-trimethylsilylpropyne

3-TRIMETHYLSILYL-2-PROPYN-1-OL Suppliers

Global( 213)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10297	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9641	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58
Antai Fine Chemical Technology Co.,Limited	58

View Lastest Price from 3-TRIMETHYLSILYL-2-PROPYN-1-OL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-03-16	3-TRIMETHYLSILYL-2-PROPYN-1-OL 5272-36-6	US $0.00-0.00 / g	10g	98%Min	1000kg	LY Global chemicals co.,ltd .
2023-03-03	3-TRIMETHYLSILYL-2-PROPYN-1-OL 5272-36-6	US $0.00-0.00 / KG	1KG	99%	20 mt	Hebei Guanlang Biotechnology Co., Ltd.
2021-08-06	3-TRIMETHYLSILYL-2-PROPYN-1-OL USP/EP/BP 5272-36-6	US $1.10 / g	1g	99.9%	100 Tons min	Dideu Industries Group Limited

3-TRIMETHYLSILYL-2-PROPYN-1-OL
5272-36-6
US $0.00-0.00 / g
98%Min
LY Global chemicals co.,ltd .

3-TRIMETHYLSILYL-2-PROPYN-1-OL
5272-36-6
US $0.00-0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

3-TRIMETHYLSILYL-2-PROPYN-1-OL USP/EP/BP
5272-36-6
US $1.10 / g
99.9%
Dideu Industries Group Limited

3-TRIMETHYLSILYL-2-PROPYN-1-OL Spectrum

3-TRIMETHYLSILYL-2-PROPYN-1-OL(5272-36-6)IR 3-TRIMETHYLSILYL-2-PROPYN-1-OL(5272-36-6)Raman

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3-Trimethylsilylpropargyl TIMTEC-BB SBB009061 TRIMETHYLSILYLPROPARGYL ALCOHOL 1-TRIMETHYLSILYLPROPARGYL ALCOHOL 3-TRIMETHYLSILYL-2-PROPYN-1-OL 3-TRIMETHYLSILYL-2-PROPYNE-1-OL 3-(trimethylsilyl)-2-propyn-1-o 3-Trimethylsilylpropargylalcohol3-Trimethylsilyl-2-propyn-1-ol 3-(Trimethylsilyl)propargyl alcohol, 98+% 3-TRIMETHYLSILYLPROPARGYL ALCOHOL, 98%3-TRIMETHYLSILYLPROPARGYL ALCOHOL, 98%3-TRIMETHYLSILYLPROPARGYL ALCOHOL, 98% 3-TRIMETHYLSILYL-2-PROPYN-1-OL USP/EP/BP 3-Trimethylsilyl-2-propyn-1-ol,99% 3-(triMethylsilyl)prop-2-yn-1-ol 3-(Trimethylsilyl)propargyl alcohol 99% 3-(TRIMETHYLSILYL)PROPARGYL ALCOHOL 3-TRIMETHYLSILANYL-PROP-2-YN-1-OL 2-Propyn-1-ol, 3-(trimethylsilyl)- 3- (trimethylmethilyl) propanyl ol 5272-36-6 CH33SiC8801CCH2OH C6H12OSi CH33SiCCCH2OH Acetylenic Alcohols & Their Derivatives Si-(C)4 Compounds Acetylenes Si (Classes of Silicon Compounds) Organic Building Blocks Internal Building Blocks Alkynes Ethynylsilanes Silicon Compounds (for Synthesis) Acetylenic Alcohols & Their Derivatives Ethynylsilanes Si (Classes of Silicon Compounds) Si-(C)4 Compounds Silicon Compounds (for Synthesis) Synthetic Organic Chemistry Acetylenes