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(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE structure

CAS No.: 132861-87-1

Chemical Name:: (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE

Synonyms: PD 81,723;4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine;(2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone;(3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone;(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE;Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]-;(2-amino-4,5-dimethyl-3-thiophenyl)-[3-(trifluoromethyl)phenyl]methanone;(2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone

CBNumber:: CB2484082

Molecular Formula:: C14H12F3NOS

Molecular Weight:: 299.31

MDL Number:: MFCD01321053

MOL File:: 132861-87-1.mol

Last updated:2023-06-30 15:45:59

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(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Properties

Melting point	100-104 °C(Solv: ligroine (8032-32-4))
Boiling point	411.7±45.0 °C(Predicted)
Density	1.328±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	DMSO: ~13 mg/mL
form	solid
pka	-1.36±0.13(Predicted)
color	yellow

SAFETY

Risk and Safety Statements

WGK Germany	3

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE price More Price(16)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	1363	PD 81,723 ≥99%(HPLC)	132861-87-1	10	$157	2021-12-16	Buy
Usbiological	256193	PD 81723	132861-87-1	10mg	$403	2021-12-16	Buy
TRC	P218318	PD 81,723	132861-87-1	10mg	$115	2021-12-16	Buy
Matrix Scientific	096431	(2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone 95+%	132861-87-1	250mg	$1890	2021-12-16	Buy
AK Scientific	6013AA	(2-Amino-4,5-dimethylthiophen-3-yl)(3-(trifluoromethyl)phenyl)methanone	132861-87-1	250mg	$2601	2021-12-16	Buy

Product number	Packaging	Price	Buy
1363	10	$157	Buy
256193	10mg	$403	Buy
P218318	10mg	$115	Buy
096431	250mg	$1890	Buy
6013AA	250mg	$2601	Buy

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Chemical Properties,Uses,Production

Uses

PD 81,723 is an allosteric potentiator that increases the functional effects of adenosine and adenosine analogs.

Biological Activity

Allosteric potentiator at the adenosine A 1 receptor; acts via agonist-dependent and -independent mechanisms. Enhances agonist affinity for, and increased t 1/2 of dissociation from, the receptor. Also inhibits basal and forskolin-stimulated adenylyl cyclase (AC) activity in A 1 receptors expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of AC. Active in vivo .

storage

Store at RT

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Preparation Products And Raw materials

Raw materials

Preparation Products

(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Suppliers

Global( 41)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Meike meditech (Foshan) Co.,Ltd	+86-0757-22239986 +86-18029359586	sales@mkmeditech.com	China	1134	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Aikon International Limited	025-58859352 18068836627	sales01@aikonchem.com	China	15085	58
BOC Sciences	--	info@bocsci.com	USA	0	65
Shanghai Haohong Pharmaceutical Co., Ltd.	400-400-8210725 4008210725	malulu@leyan.com	China	55023	58

Supplier	Advantage
Alchem Pharmtech,Inc.	58
TargetMol Chemicals Inc.	58
Meike meditech (Foshan) Co.,Ltd	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
EMMX Biotechnology LLC	60
Aikon International Limited	58
BOC Sciences	65
Shanghai Haohong Pharmaceutical Co., Ltd.	58

132861-87-1((2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE)Related Search:

3-(3-TRIFLUOROMETHYLBENZOYL)THIOPHENE 3-(3-METHYLBENZOYL)THIOPHENE (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE 3-BENZOYLTHIOPHENE (2-Amino-3-thienyl)(phenyl)methanone

2-AMINO-3-BENZOYL-4,5-DIMETHYLTHIOPHENE

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(2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE PD 81,723 (2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone (3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone 4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]- (2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone (2-amino-4,5-dimethyl-3-thiophenyl)-[3-(trifluoromethyl)phenyl]methanone 132861-87-1 C14H12F3NOS Adenosine receptor