FK BINDING PROTEIN
- CAS No.
- 131144-19-9
- Chemical Name:
- FK BINDING PROTEIN
- Synonyms
- FKBP1;PKC12;PKCI2;FKBP25;FKBP1A;fkbp-12;FKBP-1A;Rotamase;Calstabin-1;FKBP3 human
- CBNumber:
- CB2486536
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131088
- MOL File:
- Mol file
| storage temp. | 2-8°C |
|---|---|
| form | liquid |
| biological source | rabbit |
| FDA UNII | RYF5TU3245 |
| UNSPSC Code | 12352204 |
| NACRES | NA.41 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 |
| WGK Germany | 3 |
FK BINDING PROTEIN price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP6091 | FKBP1a/FKBP12 human recombinant, expressed in E. coli, ≥95% (SDS-PAGE) | 1646529-86-3 | 100μG | $516 | 2024-03-01 | Buy |
| Sigma-Aldrich | SAB1303643 | ANTI-FKBP12 (CENTER) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 131144-19-9 | 400μL | $481 | 2024-03-01 | Buy |
| Sigma-Aldrich | SRP6093 | FKBP3 human recombinant, expressed in E. coli, ≥90% (SDS-PAGE) | 131144-19-9 | 100μG | $486 | 2023-01-07 | Buy |
| Usbiological | 517213 | FK506 Binding Protein 1A | 131144-19-9 | 96Tests | $981 | 2021-12-16 | Buy |
| Usbiological | 154649 | FK506 Binding Protein 3 | 131144-19-9 | 10ug | $333 | 2021-12-16 | Buy |
FK BINDING PROTEIN Chemical Properties,Uses,Production
Biological Activity
FKFBP1A (FK506-binding protein 1A) is a peptidyl-prolyl cis-trans isomerase. It interacts with the ryanodine receptor (RyR1) and helps in maintaining intracellular Ca2+ homeostasis. It is also involved in protein folding, cell cycle and protein trafficking. In neurodegenerative diseases, FKFBP1A is dysregulated and might be associated with the pathogenesis. In human cell lines, it controls the localization and processing of amyloid precursor protein, and thus might be involved in the pathogenesis of Alzheimer′s disease. FKFBP1A is also involved in Huntington′s disease. It plays a role in the structural properties and proteotoxicity of mHTT (mutant huntingtin) aggregates.
FK BINDING PROTEIN Preparation Products And Raw materials
Raw materials
Preparation Products
FK BINDING PROTEIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10308 | 58 |
| Biolab Reagents | 18108604356 | info@biolabreagent.com | China | 9868 | 58 |
| ACROBiosystems | 18514007688 | jiaxin.zhao@acrobiosystems.com | China | 1320 | 58 |
| CUSABIO TECHNOLOGY LLC | 027-87196173 | cusabio@163.com | China | 6066 | 58 |
| ZSGB-BIO | 02-400-810-9781 400810978 | sales@zsbio.com | China | 2887 | 58 |
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 6394 | 58 |
| Beijing Biosynthesis Biotechnology Co Ltd | 400-9019800 | sales@bioss.com.cn | China | 6102 | 58 |
| Adooq Bioscience LLC | 400-025-6535 | sales@adooq.cn | China | 6215 | 58 |
| ProSpec Tany TechnoGene Ltd | 972-8947-1175 | info@prospecbio.com | China | 6874 | 58 |
| Guangzhou Zhuanyan Biotechnology Co., Ltd. | 18926165828 | CHINA | 0 | 58 |