Suprofen
- CAS No.
- 40828-46-4
- Chemical Name:
- Suprofen
- Synonyms
- Suprol;TN 762;r25061;Anemet;Srendam;Suprocil;Topalgic;Profenal;Profenol;maldocil
- CBNumber:
- CB2496867
- Molecular Formula:
- C14H12O3S
- Molecular Weight:
- 260.31
- MDL Number:
- MFCD00079572
- MOL File:
- 40828-46-4.mol
- MSDS File:
- SDS
| Melting point | 278°C |
|---|---|
| Boiling point | 373.57°C (rough estimate) |
| Density | 1.2959 (rough estimate) |
| refractive index | 1.5050 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 0.5 mg/ml |
| form | Powder |
| pka | 3.91(at 25℃) |
| Water Solubility | soluble |
| CAS DataBase Reference | 40828-46-4(CAS DataBase Reference) |
| FDA UNII | 988GU2F9PE |
| ATC code | M01AE07 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P330+P331+P310 | |||||||||
| RIDADR | 3249 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2934990002 | |||||||||
| Toxicity | LD50 (7 days post-drug) in mice, rats, guinea pigs, dogs (mg/kg): 590, 353, 280, 160 orally (Niemegeers) | |||||||||
| NFPA 704 |
|
Suprofen price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1495 | Suprofen ≥98% (HPLC) | 40828-46-4 | 5MG | $80.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1495 | Suprofen ≥98% (HPLC) | 40828-46-4 | 25MG | $261 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1642507 | Suprofen United States Pharmacopeia (USP) Reference Standard | 40828-46-4 | 200MG | $252 | 2024-03-01 | Buy |
| Cayman Chemical | 21350 | Suprofen ≥98% | 40828-46-4 | 5mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 21350 | Suprofen ≥98% | 40828-46-4 | 10mg | $115 | 2024-03-01 | Buy |
Suprofen Chemical Properties,Uses,Production
Description
Suprofen is an arylpropionic acid analgesic/antiinflammatory agent with close structural resemblance to ketoprofen. It is more potent in many assays than indomethacin and ketoprofen and appears better tolerated.
Chemical Properties
Off-White to Light-Brown
Originator
Janssen (Belgium)
Uses
Prostaglandin biosynthesis inhibitor. Analgesic
Uses
Bridged pseudopelletierine derivative; specific serotonin (5HT3) receptor antagonist. Antiemetic.
Definition
ChEBI: An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.
brand name
Profenal (Alcon);Algiamida;Algiasdi;Bordol;Erdol;Masterfen;Sufenid;Supranol;Surfex;MALDOCIL.
Veterinary Drugs and Treatments
Suprofen is a non-steroidal anti-inflammatory agent similar to flurbiprofen. Suprofen and flurbiprofen are phenylalkanoic acids that inhibit the cyclo-oxygenase enzymes responsible for conversion of arachadonic acid from cell membranes into various prostaglandins. These prostaglandins mediate certain aspects of ocular inflammation including disruption of the blood-aqueous barrier, uveal vasodilation, increases in intraocular pressure, and leakage of white blood cells and protein from uveal vessels into the aqueous humor. Prostaglandins cause iris sphincter constriction (miosis) independent of cholinergic mechanisms. Suprofen can inhibit this intraocular miosis and may also be useful in the management of uveal inflammation (usually in addition to topical steroids).
Suprofen Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Suprofen Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12452 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3842 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29627 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 | info@fortunachem.com | China | 5984 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9339 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
View Lastest Price from Suprofen manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-01 | Suprofen
40828-46-4
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2021-09-29 | Suprofen
40828-46-4
|
US $0.00-0.00 / g | 1g | 98%-102% | 100G | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2021-07-20 | Suprofen
40828-46-4
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd |