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DAPH
- CAS No.
- 145915-58-8
- Chemical Name:
- DAPH
- Synonyms
- DAPH-1 (DAPH;DAPH/CGP 52411;DAPH >=98% (HPLC), solid;1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-;4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411
- CBNumber:
- CB2498023
- Molecular Formula:
- C20H15N3O2
- Molecular Weight:
- 329.35
- MDL Number:
- MFCD00236442
- MOL File:
- 145915-58-8.mol
- MSDS File:
- SDS
Last updated:2023-09-04 15:50:00
| Melting point | 199-202℃ |
|---|---|
| Density | 1.374 |
| storage temp. | 2-8°C |
| solubility | DMSO: ~30 mg/mL |
| pka | 9.06±0.20(Predicted) |
| form | solid |
| color | orange |
| FDA UNII | Z13D008FZ2 |
DAPH price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D3943 | DAPH ≥98% (HPLC), solid | 145915-58-8 | 5mg | $198 | 2024-03-01 | Buy |
| Sigma-Aldrich | D3943 | DAPH ≥98% (HPLC), solid | 145915-58-8 | 25mg | $630 | 2024-03-01 | Buy |
| Cayman Chemical | 29196 | DAPH | 145915-58-8 | 1mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 29196 | DAPH | 145915-58-8 | 25mg | $651 | 2024-03-01 | Buy |
| Cayman Chemical | 29196 | DAPH | 145915-58-8 | 5mg | $156 | 2024-03-01 | Buy |
DAPH Chemical Properties,Uses,Production
Uses
CGP 52411 is a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitmuor activity. It may offer therapeutic agents for the treatment of hyperproliferative diseases.
Definition
ChEBI: 4,5-dianilinophthalimide is phthalimide substituted at the 4- and 5-positions by anilino groups. It has a role as a tyrosine kinase inhibitor and a geroprotector.
Biochem/physiol Actions
DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR.
DAPH Preparation Products And Raw materials
Raw materials
Preparation Products
DAPH Suppliers
Global( 30)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2784 | 58 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3444 | 55 |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28822 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
145915-58-8(DAPH)Related Search:
DAPH/CGP 52411
4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411
DAPH-1
(DAPH
1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-
DAPH >=98% (HPLC), solid
145915-58-8