ChemicalBook >> CAS DataBase List >>CYCLIC-PIFITHRIN-ALPHA
CYCLIC-PIFITHRIN-ALPHA
- CAS No.
- 60477-34-1
- Chemical Name:
- CYCLIC-PIFITHRIN-ALPHA
- Synonyms
- Pifithrin-2;Pifithrin-alpha (cyclic) . HBr;Pifithrin-β (QB-102 and Cyclic-Pifithrin-α);Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem;2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole;5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole;Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-
- CBNumber:
- CB2504209
- Molecular Formula:
- C16H16N2S
- Molecular Weight:
- 268.38
- MDL Number:
- MFCD02108837
- MOL File:
- 60477-34-1.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:07
| Melting point | 266.4-267.3 °C(lit.) |
|---|---|
| Density | 1.30±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO: 20 mg/mL |
| form | White solid |
| pka | 6.75±0.20(Predicted) |
| FDA UNII | 45I8QO7K37 |
CYCLIC-PIFITHRIN-ALPHA price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | B4813 | Pifithrin-β | 60477-34-1 | 5mg | $87 | 2021-12-16 | Buy |
| ApexBio Technology | B4813 | Pifithrin-β | 60477-34-1 | 10mg | $148 | 2021-12-16 | Buy |
| Axon Medchem | Axon3051 | Pifithrin-β-PFT-β|Z-2-035II 99% | 60477-34-1 | 2x10mg | $165 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0017104 | PIFITHRIN-B 95.00% | 60477-34-1 | 5MG | $497.16 | 2021-12-16 | Buy |
| ApexBio Technology | B4813 | Pifithrin-β | 60477-34-1 | 50mg | $607 | 2021-12-16 | Buy |
CYCLIC-PIFITHRIN-ALPHA Chemical Properties,Uses,Production
Definition
ChEBI: 2-(4-methylphenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole is a member of imidazoles.
General Description
A cell-permeable and very stable analog of Pifithrin-α (Cat. No. 506132), with similar biological function, but with reduced cytotoxicity. A chemical inhibitor of p53. Reversibly inhibits p53-dependent transactivation of p53-responsive genes; also reversibly blocks p53-mediated apoptosis. Acts as a P-gp modulator by changing relative substrate specificity of the transporter. This compound has been reported to be a potent STAT6 transcriptional inhibitor.
Biochem/physiol Actions
Cell permeable: yes
CYCLIC-PIFITHRIN-ALPHA Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 28)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3989 | 66 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
60477-34-1(CYCLIC-PIFITHRIN-ALPHA)Related Search:
Pifithrin-alpha (cyclic) . HBr
5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole
Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem
Pifithrin-2
Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-
Pifithrin-β (QB-102 and Cyclic-Pifithrin-α)
2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole
60477-34-1