2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D
- CAS No.
- 162049-83-4
- Chemical Name:
- 2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D
- Synonyms
- 2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D;2-((3-Trifluoromethyl)phenyl)histamine dimaleate >=98% (HPLC), powder
- CBNumber:
- CB2505044
- Molecular Formula:
- C12H12F3N3.2C4H4O4
- Molecular Weight:
- 487.38
- MDL Number:
- MFCD08277024
- MOL File:
- 162049-83-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H315-H318-H335 |
| Precautionary statements | P280-P301+P310+P330-P302+P352-P305+P351+P338+P310 |
| Hazard Codes | T |
| Risk Statements | 25-37/38-41 |
| Safety Statements | 26-39-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T4951 | 2-((3-Trifluoromethyl)phenyl)histamine dimaleate ≥98% (HPLC), powder | 162049-83-4 | 5mg | $195 | 2024-03-01 | Buy |
| TRC | T002700 | T4951 | 162049-83-4 | 1mg | $55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0066486 | 2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE DIMALEATE 95.00% | 162049-83-4 | 5MG | $712.12 | 2021-12-16 | Buy |
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D Chemical Properties,Uses,Production
Uses
2-((3-Trifluoromethyl)phenyl)histamine dimaleate has been used to study the induction of goblet cell secretion in rats3. 2-((3-Trifluoromethyl)phenyl)histamine dimaleate has also been used to study the role of H1 receptor in COX-2 regulation and prostanoid homeostasis in human vascular endothelial cells4.
Biochem/physiol Actions
2-((3-Trifluoromethyl)phenyl)histamine dimaleate was found to be the most potent and selective H1 histamine receptor agonist of a panel of compounds in functional in vitro studies on histamine H2, H3, and other neurotransmitter receptors. It showed better potency at the guinea pig H1 histamine receptor than at the human H1 histamine receptor (pKi : 5.9). The selectivity of 2-((3-Trifluoromethyl)phenyl)histamine dimaleate was found to be 2138 (H1:H2), > 64 (H1:H3), 1000 (H1:M3), 105 (H1: a1), 708 (H1:β1), and 71 (H1:5HT2A). 2-((3-Trifluoromethyl)phenyl)histamine dimaleate does not cross the blood-brain barrier.
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D Preparation Products And Raw materials
Raw materials
Preparation Products
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| Supplier | Advantage |
|---|---|
| Aladdin Scientific | 58 |
| Sigma-Aldrich | 80 |
| Energy Chemical | 58 |