ChemicalBook >> CAS DataBase List >>Crizotinib acetate

Crizotinib acetate

CAS No.
877399-53-6
Chemical Name:
Crizotinib acetate
Synonyms
Crizotinib acetate
CBNumber:
CB25820320
Molecular Formula:
C23H26Cl2FN5O3
Molecular Weight:
510.39
MDL Number:
MOL File:
877399-53-6.mol
Last updated:2023-03-31 09:12:58

Crizotinib acetate Chemical Properties,Uses,Production

Description

Crizotinib, also known as PF-02341066, is an orally bioavailable agent belonging to the class of c-met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors with potential antineoplastic activity. Crizotinib was approved for treatment of some non-small cell lung carcinoma (NSCLC) in the US, and undergoing clinical trials testing its safety and efficacy in anaplastic large cell lymphoma, neuroblastoma, and other advanced solid tumors in both adults and childre. Crizotinib inhibits the membrane receptor MET and activation of the MET signaling pathway, which may block tumor cell growth, migration and invasion, and tumor angiogenesis in susceptible tumor cell populations. Crizotinib was approved in 2011.

Crizotinib acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Crizotinib acetate Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24024 58
Crizotinib acetate 877399-53-6