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TOS-ARG-OME HCL

TOS-ARG-OME HCL structure

CAS No.: 1784-03-8

Chemical Name:: TOS-ARG-OME HCL

Synonyms: TAME;L-TAME;TAME,HCl;Tos-Arg-OMe;Tos-Arg-OMe¤HC;Ala-Ala-Ala-OMe;TOS-ARG-OME HCL;H-Tos-Arg-OMe·HCl;Tos-L-Arg-OMe*HCl;TAME HYDROCHLORIDE

CBNumber:: CB2669913

Molecular Formula:: C14H23ClN4O4S

Molecular Weight:: 378.87

MDL Number:: MFCD00012578

MOL File:: 1784-03-8.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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TOS-ARG-OME HCL Properties

Melting point	145-147(lit.)
alpha	-14 º (c=4, H2O)
refractive index	-14 ° (C=4, H2O)
storage temp.	-20°C
solubility	methanol: 50 mg/mL, clear, colorless
form	Fine Crystalline Powder
color	White
BRN	3922357
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChIKey	JIQFFACVQXXHMY-YDALLXLXSA-N
CAS DataBase Reference	1784-03-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08,GHS09,GHS02
Signal word	Danger
Hazard statements	H319-H361-H371-H336-H304-H411-H224
Precautionary statements	P501-P273-P260-P270-P202-P240-P210-P233-P201-P243-P241-P242-P271-P264-P280-P370+P378-P391-P331-P337+P313-P305+P351+P338-P308+P311-P303+P361+P353-P301+P310-P304+P340+P312-P403+P233-P403+P235-P405
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25-37/39-26
WGK Germany	3
F	3-10
HS Code	29252900

TOS-ARG-OME HCL price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T4626	Nα-p-Tosyl-L-arginine methyl ester hydrochloride	1784-03-8	5g	$61.9	2024-03-01	Buy
Sigma-Aldrich	172104	Anaphase-Promoting Complex Inhibitor, TAME	1784-03-8	50mg	$85.2	2024-03-01	Buy
TCI Chemical	T0330	Nα-Tosyl-L-arginine Methyl Ester Hydrochloride >98.0%(T)	1784-03-8	1g	$26	2024-03-01	Buy
TCI Chemical	T0330	Nα-Tosyl-L-arginine Methyl Ester Hydrochloride >98.0%(T)	1784-03-8	25g	$207	2024-03-01	Buy
Cayman Chemical	17550	N-4-Tosyl-L-arginine methyl ester (hydrochloride) ≥98%	1784-03-8	5g	$44	2024-03-01	Buy

Product number	Packaging	Price	Buy
T4626	5g	$61.9	Buy
172104	50mg	$85.2	Buy
T0330	1g	$26	Buy
T0330	25g	$207	Buy
17550	5g	$44	Buy

TOS-ARG-OME HCL Chemical Properties,Uses,Production

Description

TAME (1784-03-8) binds to the ubiquitin ligase anaphase-promoting complex (APC) preventing its activation by Cdc20 and Cdh1 and resulting in mitotic arrest.1,2

Chemical Properties

white fine crystalline powder

Uses

enzyme inhibitor

Uses

N-4-Tosyl-L-arginine Methyl Ester Hydrochloride acts as a synthetic substrate of serine proteases and thus is used to determine serine proteases from diverse organic sources.

Uses

Substrate for trypsin, thrombin, plasmin and other proteases.

Biochem/physiol Actions

Nα-p-Tosyl-L-arginine methyl ester (TAME) binds to anaphase-promoting complex (APC) and prevents its activation by Cdc20 and Cdh1.

References

1) Zeng et al. (2010) Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage; Cancer Cell, 18 382 2) Zeng and King (2012) An APC/C inhibitor stabilizes Cyclin B1 by prematurely terminating ubiquitination; Nat. Chem. Biol., 8 383

TOS-ARG-OME HCL Preparation Products And Raw materials

Raw materials

Preparation Products

TOS-ARG-OH

TOS-ARG-OME HCL Suppliers

Global( 266)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
GenicBio Limited	58
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from TOS-ARG-OME HCL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-04-17	Tos-Arg-OMe·HCl 1784-03-8	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
	2019-07-06	TOS-ARG-OME HCL 1784-03-8	US $1.00 / KG	1KG	99%	20kg	Career Henan Chemical Co

Tos-Arg-OMe·HCl
1784-03-8
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

TOS-ARG-OME HCL
1784-03-8
US $1.00 / KG
99%
Career Henan Chemical Co

TOS-ARG-OME HCL Spectrum

TOS-ARG-OME HCL(1784-03-8)¹HNMR TOS-ARG-OME HCL(1784-03-8)IR TOS-ARG-OME HCL(1784-03-8)FT-IR TOS-ARG-OME HCL(1784-03-8)Raman

1784-03-8(TOS-ARG-OME HCL)Related Search:

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DL-Ornithine hydrochloride L-Ornithine Ethyl-p-toluenesulfonamide N-P-TOSYLGLYCINE L-Alanine methyl ester hydrochloride

2-(TOLUENE-4-SULFONYLAMINO)-PROPIONIC ACID H-NVA-OME HCL L-Arginine hydrochloride TOS-ARG-OH N-Butyltoluene-4-sulfonamide

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1of4

N-4-Tosyl-L-arginine methyl ester hydrochloride N-Alpha-p-tosyl-l-arginine methyl ester hydrochloride ,99% Ala-Ala-Ala-OMe L-Ala-L-Ala-L-Ala-OMe Nα-Tosyl-L-arginine methyl·hydrochloric acid Nalpha-4-Tosyl-L-arginine methyl ester hydrochloride,99% N-ａ-Tosyl-L-Arginine methyl ester hydrochloride Tos-Arg-Ome x HCl ,≥99% Nα-p-Tosyl-L-arginine methyl ester hydrochloride,TAME hydrochloride N-alpha-p-TOSYL-L -ARGININE METHYL ESTER H-Tos-Arg-OMe·HCl TAME Nalpha-p-Toluenesulfonyl-L-arginine Methyl Ester Hydrochloride Tos-Arg-OMe.HCl (S)-Methyl 5-guanidino-2-(4-MethylphenylsulfonaMido)pentanoate hydrochloride Nalpha-4-Tosyl-L-arginine Methyl ester hydrochloride, 99% 10GR N^α-p-Tosyl-L-arginine Methyl ester hydrochloride methyl (2S)-5-(diaminomethylideneamino)-2-[(4-methylphenyl)sulfonylamino]pentanoate,hydrochloride Na-p-Toluenesulfonyl-L-arginine Methyl ester HC1 Tos-Arg-OMe P-TOSYL-L-ARG METHYL ESTER HCL P-TOLUENESULFONYL-L-ARGININE METHYL ESTER HCL P-TOLUENESULFONYL-L-ARGININE METHYL ESTER HYDROCHLORIDE N-P-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE N-ALPHA-4-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE N-ALPHA-TOLUENESULFONYLARGININE METHYL ESTER HYDROCHLORIDE NALPHA-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE N-ALPHA-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE SALT NALPHA-P-TOLUENESULFONYL-L-ARGININE METHYL ESTER HYDROCHLORIDE NALPHA-P-TOSYL-L-ARGININE METHYL ESTER HCL N-ALPHA-P-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE N-ALPHA-P-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE SALT N-A-P-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE TAME TAME HYDROCHLORIDE TOS-ARGININE-OME HCL TOS-ARG-OME HCL TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE TOSYL-L-ARGININE METHYL ESTER MONOHYDROCHLORIDE ALPHA-N-P-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE L-Arginine, N2-(4-methylphenyl)sulfonyl-, methyl ester, monohydrochloride N(ALPHA)-TOSYL-L-ARGININE METHYL ESTER & TOS-ARG-OME·HCL,NA-P-TOSYL-L-ARGININE METHYL ESTER HYDROCHLORIDE NALPHA-(4-TOLUENESULFONYL)-L-ARGININE METHYL ESTER HYDROCHLORIDE P-Tosyl-L-ArginineMethylEster TAME,HCl L-TAME TAME ~-N-p-Tosyl-L-arginine methyl ester hydrochloride methyl N2-[(p-tolyl)sulphonyl]-L-argininate monohydrochloride N-α-Tosyl-L-arginine methyl ester hydrochloride Methyl N-{2}-[(p-tolyl)sulfonyl]-L-argininate monohydrochloride. P-Tosyl-l-arginine methyl ester HCL N-alpha-p-Toluolsulfonyl-L-arginine methyl ester hydrochloride Tos-L-Arg-OMe*HCl NA-P-TOSYL-L-ARGININE METHYL*ESTER H Tos-Arg-OMe¤HC Nα-Tosyl-L-arginine methyl ester hydrochloride≥ 98% (HPLC) Anaphase-Promoting Complex Inhibitor, TAME Methyl N-[(p-tolyl)sulphonyl]-L-argininate monohydrochloride TOS-ARG-OME hydrochloride