HUMAN MCP-1
- CAS No.
- 126463-99-8
- Chemical Name:
- HUMAN MCP-1
- Synonyms
- JE;MCAF;CCL2;MCP-1;RHMCP-1;HUMAN MCAF;HUMAN CCL2;HUMAN MCP-1;HC11, HUMAN;MCAF, HUMAN
- CBNumber:
- CB2680840
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131621
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
Safety Statements | 22-24/25 |
---|---|
WGK Germany | 3 |
HS Code | 3504009000 |
HUMAN MCP-1 price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | M6667 | Monocyte Chemotactic Protein-1 human ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture | 126463-99-8 | 10μg | $313 | 2024-03-01 | Buy |
Sigma-Aldrich | SRP3109 | MCP-1/MCAF human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 126463-99-8 | 20μG | $419 | 2023-06-20 | Buy |
Usbiological | M1203-02T | Monocyte Chemotactic Protein-1 | 126463-99-8 | 10ug | $468 | 2021-12-16 | Buy |
Usbiological | M1203-03B | Monocyte Chemotactic Protein 1 | 126463-99-8 | 100ug | $267 | 2021-12-16 | Buy |
Usbiological | 026855 | Monocyte Chemotactic Protein 1 | 126463-99-8 | 96Tests | $668 | 2021-12-16 | Buy |
HUMAN MCP-1 Chemical Properties,Uses,Production
Uses
Monocyte chemoattractant protein-1/monocyte chemotactic and activating factor (MCP-1/MCAF) has been used:
- as a chemokine supplement in the alpha minimal essential medium for culturing neurons to test its effect on JmjC histone demethylase (Jmjd2a) mRNA
- as a component of Dulbecco′s Modified Eagle (DMEM) medium, as a positive chemoattractant control in HeLa cells for migration assay
- as a chemoattractant to induced macrophage chemotaxis
General Description
Monocyte chemoattractant protein-1/monocyte chemotactic and activating factor (MCP-1/MCAF), also called the C-C motif chemokine ligand 2 (CCL2), is an inflammatory cytokine. The CCL2 gene is mapped to human chromosome 17q12. CCL2 is present in epithelial, endothelial, mesangial and microglial cells. Structurally, it dimerizes and has four regions of the ?-sheet. Recombinant human MCP-1 is a 8.6 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues. The MCP family cross-reacts across species.
Biochem/physiol Actions
Monocyte chemoattractant protein-1/monocyte chemotactic and activating factor (MCP-1/MCAF) acts as a human immunodeficiency virus 1 (HIV-1) suppressor. The MCP-1 acts as a chemoattractant for T cells and natural killer (NK) cells. It also plays a key role in the migration and infiltration of macrophages. CCL2 shows under expression in high-grade ovarian serous carcinomas (HGOSCs) and is expressed less in epithelial ovarian cancer (EOC).
HUMAN MCP-1 Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN MCP-1 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Nanjing TGpeptide | +86-13347807150 +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696; | info@hanhongsci.com | China | 42982 | 64 |
Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |
Nanjing TGpeptide Biotechnology Co.,Ltd. | 18115476705 | sales@tgpeptide.com | China | 3189 | 58 |
Wuhan Chemstan Biotechnology Co., Ltd. | 15926423062 | 422450190@qq.com | China | 10132 | 58 |
Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 6633 | 58 |
Nanjing Yuanpeptide Biotech Co.,Ltd. | 18168071971 | support@yuan-peptide.com | China | 2977 | 58 |
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