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Enoximone

Enoximone structure

CAS No.: 77671-31-9

Chemical Name:: Enoximone

Synonyms: Perfan;Pedane;RMI-17043;ENOXIMONE;MDL-17043;Fenoximone;Enoximone USP/EP/BP;4-Methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one;1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE;4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one

CBNumber:: CB2682723

Molecular Formula:: C12H12N2O2S

Molecular Weight:: 248.3

MDL Number:: MFCD00867130

MOL File:: 77671-31-9.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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Enoximone Properties

Melting point	255-258°C
Density	1.33
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO: 28 mg/mL, soluble
pka	10.37±0.70(Predicted)
form	solid
color	light yellow
CAS DataBase Reference	77671-31-9(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	C7Z4ITI7L7
ATC code	C01CE03

SAFETY

Risk and Safety Statements

RIDADR	3249
WGK Germany	3
HazardClass	6.1(b)
PackingGroup	III

Enoximone price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	E1279	Enoximone solid	77671-31-9	10mg	$270	2024-03-01	Buy
Sigma-Aldrich	E1279	Enoximone solid	77671-31-9	50mg	$905	2022-05-15	Buy
Tocris	1693	Enoximone ≥99%(HPLC)	77671-31-9	10	$169	2021-12-16	Buy
Tocris	1693	Enoximone ≥99%(HPLC)	77671-31-9	50	$711	2021-12-16	Buy
Usbiological	255248	Enoximone	77671-31-9	10mg	$423	2021-12-16	Buy

Product number	Packaging	Price	Buy
E1279	10mg	$270	Buy
E1279	50mg	$905	Buy
1693	10	$169	Buy
1693	50	$711	Buy
255248	10mg	$423	Buy

Enoximone Chemical Properties,Uses,Production

Description

Enoximone is a phosphodiesterase inhibitor indicated for selective use as a cardiostimulant in heart transplant patient maintenance. It is currently being investigated for other indications including acute congestive heart failure.

Originator

Merrell Dow (USA)

Uses

Enoximone is a phosphodiesterase inhibitor used in the treatment of congestive heart failure and is selective to phosphodiesterase 3. Potent PDE-3 inhibitor.

Definition

ChEBI: Enoximone is an aromatic ketone.

brand name

Perfan IV

Biological Activity

Inhibitor of type III phosphodiesterase (PDE3). Increases intracellular cyclic AMP (cAMP) concentrations and enhances myocardial contractility. Also induces concentration-dependent vasodilation in vitro .

Biochem/physiol Actions

Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE. Increased cAMP results in enhanced contractility of the heart.

storage

Store at +4°C

Enoximone Preparation Products And Raw materials

Raw materials

NITROUS ACID Ethyl acetate

Preparation Products

Enoximone Suppliers

Global( 98)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9358	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ZHEJIANG JIUZHOU CHEM CO., LTD	+86-0576225566889 +86-13454675544	admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com	China	20000	58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd	027-88013699 17354350817	Ryan@jiutian-bio.com	China	7433	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Dideu Industries Group Limited	58
TargetMol Chemicals Inc.	58
ZHEJIANG JIUZHOU CHEM CO., LTD	58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

View Lastest Price from Enoximone manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-08-13	Enoximone USP/EP/BP 77671-31-9	US $1.10 / g	1g	99.9%	100 Tons min	Dideu Industries Group Limited
	2021-01-06	Enoximone 77671-31-9	US $1.00 / g	1g	85.0-99.8%	20tons	Career Henan Chemica Co

Enoximone USP/EP/BP
77671-31-9
US $1.10 / g
99.9%
Dideu Industries Group Limited

Enoximone
77671-31-9
US $1.00 / g
85.0-99.8%
Career Henan Chemica Co

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4,5-DIMETHYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE 4-ACETYL-5-METHYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE enoximone sulfoxide

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ENOXIMONE 2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-(4-(methylthio)benzoyl)- Fenoximone MDL-17043 Pedane Perfan RMI-17043 4-methyl-5-(4-methylsulfanylbenzoyl)-1,3-dihydroimidazol-2-one 1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE 4-Methyl-5-[4-(methylthio)benzoyl]-1,3-dihydro-2H-imidazol-2-one Enoximone USP/EP/BP 4-Methyl-5-(4-(methylthio)benzoyl)-1H-imidazol-2(3H)-one inhibit,Enoximone,bronchodilatory,CD11b,eosinophils,vasodilating,Phosphodiesterase (PDE),airway,cAMP,PDE3,PDE4A,Inhibitor,anti-inflammatory,Antiasthma 77671-31-9 BioChemical Cell Signaling and Neuroscience G Proteins and Cyclic Nucleotides Phosphodiesterase Inhibitors Cyclic Nucleotide Metabolism Cell Biology APIs API