ChemicalBook >> CAS DataBase List >>4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID

CAS No.
53005-05-3
Chemical Name:
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
Synonyms
DIDS, Disodium Salt - CAS 53005-05-3;4,4'-Diisothiocyatostilbene-2,2'-disulfonic acid;4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid;4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID;4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid;4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid;4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid;2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid);Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato-;4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt
CBNumber:
CB2683689
Molecular Formula:
C16H10N2O6S4
Molecular Weight:
454.52
MDL Number:
MFCD00065493
MOL File:
53005-05-3.mol
Last updated:2023-05-04 17:34:39

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Properties

Melting point >400°C
Density 1.54±0.1 g/cm3(Predicted)
pka -1.32±0.50(Predicted)
FDA UNII QHR3Z2PN8M

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
HazardClass  IRRITANT-HARMFUL

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 309795 DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem 53005-05-3 250mg $196 2024-03-01 Buy
American Custom Chemicals Corporation CHM0024866 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID 95.00% 53005-05-3 1G $671.86 2021-12-16 Buy
American Custom Chemicals Corporation CHM0024866 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID 95.00% 53005-05-3 5G $1052.67 2021-12-16 Buy
AHH MT-10026 4,4'-Diisothiocyanatostilbene-2,2'-disulfonicacid 98% 53005-05-3 50g $628 2021-12-16 Buy
Product number Packaging Price Buy
309795 250mg $196 Buy
CHM0024866 1G $671.86 Buy
CHM0024866 5G $1052.67 Buy
MT-10026 50g $628 Buy

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Solid

Uses

Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprot

Uses

Ion channel inhibitor; especially of anion transport.

Definition

ChEBI: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid is an arenesulfonic acid.

General Description

Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.

Biochem/physiol Actions

Primary TargetCl- uptake

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Suppliers

Global( 30)Suppliers
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TargetMol Chemicals Inc.
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TargetMol Chemicals Inc. 021-33632979 15002134094 marketing@targetmol.com China 7934 58
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3069 58
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID 2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid) 4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid 4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato- 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid 5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid 4,4'-Diisothiocyatostilbene-2,2'-disulfonic acid DIDS, Disodium Salt - CAS 53005-05-3 53005-05-3 C16H10N2O6S4 Cross Linking Reagents Fluorescent Labels & Indicators