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2,4-Dichloro-5-fluoropyrimidine

2,4-Dichloro-5-fluoropyrimidine structure

CAS No.: 2927-71-1

Chemical Name:: 2,4-Dichloro-5-fluoropyrimidine

Synonyms: 5-FLUORO-2,4-DICHLOROPYRIMIDINE;oro-5-fL;NSC 70442;uoropyrimidine;CHEMPACIFIC 37950;Fluorouracil Impurity 9;2,6-DICHLORO-5-FLUORORACIL;2,4-Dichloro-5-fluorouracil;4-Dichloro-5-fluoropyriMidine;2,4-dichloro5-fluropyrimidine

CBNumber:: CB2683700

Molecular Formula:: C4HCl2FN2

Molecular Weight:: 166.97

MDL Number:: MFCD00233551

MOL File:: 2927-71-1.mol

MSDS File:: SDS

Last updated:2023-06-13 12:09:43

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2,4-Dichloro-5-fluoropyrimidine Properties

Melting point	37-41 °C (lit.)
Boiling point	80 °C / 16mmHg
Density	1.605±0.06 g/cm3(Predicted)
Flash point	223 °F
storage temp.	Inert atmosphere,2-8°C
solubility	soluble in Chloroform, Methanol
pka	-3.96±0.29(Predicted)
form	Powder or Crystalline Powder or Low Melting Solid
color	White to pale brown
Sensitive	Moisture Sensitive
InChI	InChI=1S/C4HCl2FN2/c5-3-2(7)1-8-4(6)9-3/h1H
InChIKey	WHPFEQUEHBULBW-UHFFFAOYSA-N
SMILES	C1(Cl)=NC=C(F)C(Cl)=N1
CAS DataBase Reference	2927-71-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H314

Precautionary statements

P260-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338

Hazard Codes

Xi,C

Risk Statements

36/37/38-34-22

Safety Statements

26-36-37/39-45-36/37/39

RIDADR

3261

WGK Germany

Hazard Note

Irritant

HazardClass

PackingGroup

Ⅲ

HS Code

29335990

NFPA 704

	1
3		1

2,4-Dichloro-5-fluoropyrimidine price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	653233	2,4-Dichloro-5-fluoropyrimidine 97%	2927-71-1	1g	$32.1	2024-03-01	Buy
TCI Chemical	D3374	2,4-Dichloro-5-fluoropyrimidine >98.0%(GC)	2927-71-1	5g	$20	2024-03-01	Buy
TCI Chemical	D3374	2,4-Dichloro-5-fluoropyrimidine >98.0%(GC)	2927-71-1	25g	$78	2024-03-01	Buy
Alfa Aesar	H26288	5-Fluoro-2,4-dichloropyrimidine, 98%	2927-71-1	5g	$58.6	2021-12-16	Buy
Alfa Aesar	H26288	5-Fluoro-2,4-dichloropyrimidine, 98%	2927-71-1	1g	$21.1	2021-12-16	Buy

Product number	Packaging	Price	Buy
653233	1g	$32.1	Buy
D3374	5g	$20	Buy
D3374	25g	$78	Buy
H26288	5g	$58.6	Buy
H26288	1g	$21.1	Buy

2,4-Dichloro-5-fluoropyrimidine Chemical Properties,Uses,Production

Chemical Properties

2,4-Dichloro-5-fluoropyrimidine is Yellow to Orange Crystalline Solid

Uses

2,4-Dichloro-5-fluoropyrimidine is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors. It is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors.

Uses

2,4-Dichloro-5-fluoropyrimidine can be used as a starting material to synthesize:

5-fluoropyrimidine-2-carboxamides and 5-fluoropyrimidine-4-carboxamides as potential kinase inhibitors.
A series of 2,4-diamino-5-fluoropyrimidine derivatives as potential protein kinase Cθ inhibitors.
2,4-Bisanilinopyrimidine derivatives as potential aurora kinases inhibitors.
5-fluoro-N,N-bis(4-methoxyphenyl)-2,4-pyrimidinediamine by reacting with p-methoxy aniline in the presence of DIPEA.
2-chloro-5-fluoro-4-(4-fluorophenyl)pyrimidine by Suzuki coupling reaction in the presence of (4-fluorophenyl)boronic acid triphenylphosphine, and palladium(II) acetate catalyst.
5-fluoro-2-(piperidin-4-yloxy)pyrimidin-4-amine, a scaffold, which is used in the preparation of potent deoxycytidine kinase inhibitors.

Flammability and Explosibility

Not classified

2,4-Dichloro-5-fluoropyrimidine synthesis

Synthesis of 2,4-Dichloro-5-fluoropyrimidine from 5-Fluorouracil

2,4-Dichloro-5-fluoropyrimidine Preparation Products And Raw materials

Raw materials

N,N-Dimethylaniline 5-Fluorouracil

Preparation Products

Fluorocytosine Pyrimidine, 2-amino-4-chloro-5-fluoro- (7CI,8CI) 1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)- 4-(2-chloro-5-fluoro-pyrimidin-4-yl)-morpholine (2-chloro-5-fluoro-pyrimidin-4-yl)-phenyl-amine

2-Chloro-5-fluoro-4-thiocyanopyrimidine 2-chloro-4-benzyloxy-5-fluoropyrimidine Pyrimidine, 2-chloro-5-fluoro-4-(2-fluoro-4-pyridinyl)- 2-Chloro-N-cyclopropyl-5-fluoropyrimidin-4-amine 2-Chloro-4-ethoxy-5-fluoropyriMidine

6-(2-chloro-5-fluoropyriMidin-4-ylaMino)-2,2-diMethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

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2,4-Dichloro-5-fluoropyrimidine Suppliers

Global( 471)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jiangsu Guiren Medicine Co.,Ltd	+86-13815020719 +86-13815020719	guiren_medicine@163.com	China	93	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
China Synchem Technology Co.,Ltd.	+86-0552-4929304 +86-18055277008	wangxuhui1985@126.com	China	55	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58

Supplier	Advantage
Jiangsu Guiren Medicine Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
China Synchem Technology Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58

View Lastest Price from 2,4-Dichloro-5-fluoropyrimidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-17	2,4-Dichloro-5-fluoropyrimidine 2927-71-1	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
2023-06-14	2,4-Dichloro-5-fluoropyrimidine 2927-71-1	US $5.00-2.00 / KG	1KG	99%	10000kg	Hebei Guanlang Biotechnology Co,.LTD
2022-09-29	2,4-Dichloro-5-fluoropyrimidine 2927-71-1	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

2,4-Dichloro-5-fluoropyrimidine
2927-71-1
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

2,4-Dichloro-5-fluoropyrimidine
2927-71-1
US $5.00-2.00 / KG
99%
Hebei Guanlang Biotechnology Co,.LTD

2,4-Dichloro-5-fluoropyrimidine
2927-71-1
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

2,4-Dichloro-5-fluoropyrimidine Spectrum

2,4-Dichloro-5-fluoropyrimidine(2927-71-1)¹HNMR

2927-71-1(2,4-Dichloro-5-fluoropyrimidine)Related Search:

4-Bromo-2,6-difluorobenzoic acid 2,4-Dichloropyrimidine 5-Fluoropyrimidine Fluorocytosine 2-Chloro-5-fluoropyrimidine

2,4-Dichloro-5-methylpyrimidine Dichlorofluoroethane 4,6-Dichloro-5-fluoropyrimidine FMOC-D-3-Trifluoromethylphe 2-Fluoro-3,5-dichloropyridine

2,4-DICHLORO-6-ETHYL-5-FLUOROPYRIMIDINE 3,5-DICHLORO-4-FLUOROPYRIDINE 2-AMINO-4,6-DICHLORO-5-FLUOROPYRIMIDINE 2,4-DICHLORO-6-FLUOROPYRIMIDINE 2,4,6-TRICHLORO-5-FLUOROPYRIMIDINE

Pyrimidine, 4-chloro-5-fluoro- (9CI) 2,4-Dichloro-5-fluoropyrimidine 2,4-dichloro-5-fluoro-6-methylpyrimidine

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CHEMPACIFIC 37950 2,4-DICHLORO-5-FLUOROPYRIMIDINE 2,4-Dichloro-5-fluorouracil 5-Fluoro-2,4-dichloropyrimdine 2,6-DICHLORO-5-FLUORORACIL 2,4-Dichloro-5-Fluoropyrimidin 2,4-Dichloro-5-fluoropyrimidine99% 2,4-Dichloro-5-fluoropyrimidine ,98% 2,4-Dicloro-5-fluoro pyrimidin 4-Dichloro-5-fluoropyriMidine 2,4-Dichloro-5-fluorpyriMidine 2,4-Dichloro-5-fluoro-1,3-diazine PyriMidine, 2,4-dichloro-5-fluoro- 4-(2-vinyl-1,3-dioxolan-4-yl)butan-1-ol 2,6-Dichloro-5-fluoropyriMidine NSC 70442 2,4-two chloro-5- fluorouracil 5-Fluoro-2,4-dichloropyrimidine,98% Pyrimidine, 5-fluoro-2,4-dichloro- 2,4-Dichloro-5-fluoropyrimidine (Abemaciclib Mesylate) oro-5-fL uoropyrimidine 5-fluoro-2,4-dichloropirimidine 2,4-Dichloro-5-fluoropyrimidine> 2,4-Dichloro-5-fluoropyrimidine ISO 9001：2015 REACH 2,4-dichloro5-fluropyrimidine TIANFU CHEM 2,4-Dichloro-5-fluoropyrimidine 5-FLUORO-2,4-DICHLOROPYRIMIDINE 2,4-Dichloro-5-fluoropyrimidine?New Fluorouracil Impurity 9 2927-71-1 2927-71-7 C4HCl2FN2 C4HCl2FN2O2 C4HCI2FN2 C4HN2Cl2F Building Blocks Heterocyclic Building Blocks Halogenated Heterocycles Pyrimidines Fluorine series Aromatics Bases & Related Reagents Nucleotides Pyrazines, Pyrimidines & Pyridazines Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyrimidines PyrimidinesHeterocyclic Building Blocks Building Blocks Fluorinated Nucleotides and Nucleosides Pyridines, Pyrimidines, Purines and Pteredines pharmacetical Halides Pyrazines, Pyrimidines & Pyridazines Pyrimidine