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ETH 1001

CAS No.
58801-34-6
Chemical Name:
ETH 1001
Synonyms
CA 1001;ETH 1001;Einecs 261-449-8;CALCIUM IONOPHORE;CALCIUM IONOPHORE I;, function tested, ≥CA 1001 - CAS 58801-34-6 - Calbiochem;FLUKABRAND SELECTOPHORE, CALCIUM*IONOPHORE I;(4R,5R)-N,N'-Bis[11-(ethoxycarbonyl)undecyl]-N,N',4,5-tetramethyl-3,6-dioxaoctanediamide;(-)-(R,R)-N,N'-BIS[11-(ETHOXYCARBONYL)UNDECYL]-N,N',4,5-TETRAMETHYL-3,5-DIOXAOCTANEDIAMIDE
CBNumber:
CB2683876
Molecular Formula:
C38H72N2O8
Molecular Weight:
684.99
MDL Number:
MOL File:
58801-34-6.mol
Last updated:2023-06-08 09:03:09

ETH 1001 Properties

Boiling point 715.1±50.0 °C(Predicted)
Density 1.000±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in DMSO
form Light yellow, translucent, highly viscous oil
pka -0.52±0.70(Predicted)
BRN 2343275

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
WGK Germany  3
9-23
NFPA 704
3
2 0

ETH 1001 price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 21192 Calcium ionophore I Selectophore?, function tested, ≥99.0% 58801-34-6 50mg $675 2024-03-01 Buy
Sigma-Aldrich 21192 Calcium ionophore I Selectophore?, function tested, ≥99.0% 58801-34-6 250mg $2380 2024-03-01 Buy
Sigma-Aldrich 205535 CA 1001 A neutral ionophore with extremely high selectivity for Ca 58801-34-6 25mg $294 2023-01-07 Buy
Cayman Chemical 17407 Calcium Ionophore I ≥95% 58801-34-6 5mg $64 2024-03-01 Buy
Cayman Chemical 17407 Calcium Ionophore I ≥95% 58801-34-6 10mg $121 2024-03-01 Buy
Product number Packaging Price Buy
21192 50mg $675 Buy
21192 250mg $2380 Buy
205535 25mg $294 Buy
17407 5mg $64 Buy
17407 10mg $121 Buy

ETH 1001 Chemical Properties,Uses,Production

Description

Calcium ionophore I is a Ca2+-selective ionophore for biological membranes that can be used in microelectrodes for the determination of intracellular Ca2+-activities and of slowly changing Ca2+ levels.

Purification Methods

This is a neutral Ca selectophore. It can be purified by thick layer (2mm) chromatography (Kieselgel F245) and eluted with Me2CO/CHCl3 (2:1). [Ammann et al. Helv Chim Acta 56 1780 1973, Simon & Carafoli Methods Enzymol 56 439 1977.]

References

dagostino m, lee co. neutral carrier na+- and ca2+-selective microelectrodes for intracellular application. biophys j. 1982 dec;40(3):199-207.caroni p, gazzotti p, vuilleumier p, et al. ca2+ transport mediated by a synthetic neutral ca2+ -ionophore in biological membranes. biochim biophys acta. 1977 nov 1;470(3):437-45.hinds tr, vincenzi ff. the effect of eth 1001 on ion fluxes across red blood cell membranes. cell calcium. 1985 jun;6(3):265-79.lücke a, lehmenkühler a, speckmann ej. the influence of the convulsant pentylenetetrazol on ca2+-selective microelectrodes (neutral carrier eth 1001). j neurosci methods. 1989 aug;29(2):139-42.lee mh, yoo cl, lee js, et al. tweezer-type neutral carrier-based calcium-selective membrane electrode with drastically reduced anionic interference. anal chem. 2002 jun 1;74(11):2603-7.

ETH 1001 Preparation Products And Raw materials

Raw materials

Preparation Products

ETH 1001 Suppliers

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(-)-(R,R)-N,N'-BIS[11-(ETHOXYCARBONYL)UNDECYL]-N,N',4,5-TETRAMETHYL-3,5-DIOXAOCTANEDIAMIDE (-)-(R,R)-N,N'-BIS-[11-(ETHOXYCARBONYL)UNDECYL]-N,N'-4,5-TETRAMETHYL-3,6-DIOXAOCTANEDIAMIDE CA 1001 CALCIUM IONOPHORE I CALCIUM IONOPHORE ETH 1001 DIETHYL-N,N'-[(4R,5R)-4,5-DIMETHYL-1,8-DIOXO-3,6-DIOXAOCTAMETHYLENE]BIS(12-METHYLAMINODODECANOATE) diethyl [R-(R*,R*)]-13,17,18,22-tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontanedioate FLUKABRAND SELECTOPHORE, CALCIUM*IONOPHORE I ETH 1001, (-)-(R,R)-N,Nμ-Bis-[11-(ethoxycarbonyl)undecyl]-N,Nμ,4,5-tetramethyl-3,6-dioxaoctane-diamide, Diethyl N,Nμ-[(4R,5R)-4,5-dimethyl-1,8-dioxo-3,6-dioxaoctamethylene]bis(12-methylaminododecanoate) (17R,18R)-13,17,18,22-Tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontanedioic acid diethyl ester (4R,5R)-N,N'-Bis[11-(ethoxycarbonyl)undecyl]-N,N',4,5-tetramethyl-3,6-dioxaoctanediamide 12,12'-[[(1R,2R)-1,2-Dimethylethylene]bis[oxymethylenecarbonyl(methylimino)]]bisdodecanoic acid diethyl ester 16,19-Dioxa-13,22-diazatetratriacontanedioic acid, 13,17,18,22-tetramethyl-14,21-dioxo-, diethyl ester, (R-(R*,R*))- Diethyl (R-(R*,R*))-13,17,18,22-tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontanedioate Einecs 261-449-8 (-)-(R,R)-N,N'-[Bis(11-ethoxycarbonyl)undecyl]-N,N',4,5-tetramethyl-3,6-dioxooctanediamide CA 1001 - CAS 58801-34-6 - Calbiochem 16,19-Dioxa-13,22-diazatetratriacontanedioic acid, 13,17,18,22-tetramethyl-14,21-dioxo-, 1,34-diethyl ester, (17R,18R)- , function tested, ≥ 58801-34-6 C38H72N2O8 Analytical Chromatography Product Catalog Ion Sensor Materials Ionophores Potentiometric for ISE