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Hypericin

Hypericum perforatum extracts Indications Uses
Hypericin
Hypericin structure
CAS No.
548-04-9
Chemical Name:
Hypericin
Synonyms
VIMRxyn;CYCLOSAN;HYPERICIN;Hypericine;Hypericins;MYCOPOPHYRIN;CYCLO-WERROL;HYPERICIN(P);MYCOPORPHYRIN;HYPERICUM RED
CBNumber:
CB2696784
Molecular Formula:
C30H16O8
Formula Weight:
504.44
MOL File:
548-04-9.mol

Hypericin Properties

Melting point:
299-301°C
RTECS 
SF8472000
storage temp. 
Store at +4°C
solubility 
1 M NaOH: 10 mg/mL
form 
powder
color 
black
Water Solubility 
Soluble in ethanol, dimethyl sulfoxide, methanol, acetone, ethylmethylketone, pyridine and sodium hydroxide. Insoluble in water.
Sensitive 
Light Sensitive
Merck 
14,4863
BRN 
1917913
InChIKey
BTXNYTINYBABQR-UHFFFAOYSA-N
CAS DataBase Reference
548-04-9(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280-P301+P312+P330-P261-P280g-P301+P312a-P321-P333+P313-P501a
Hazard Codes  Xn
Risk Statements  22-40-43
Safety Statements  22-36-36/37
RIDADR  2811
WGK Germany  3
8
HS Code  29145090

Hypericin price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 400076-M Hypericin Polycyclic dione that has anti-retroviral activity. 548-04-9 1mg-m $152 2018-11-20 Buy
Sigma-Aldrich 00190585 Hypericin primary pharmaceutical reference standard 548-04-9 10mg $653 2018-11-13 Buy
Alfa Aesar H26425 Hypericin, 98% 548-04-9 100mg $1450 2018-11-13 Buy
Alfa Aesar H26425 Hypericin, 98% 548-04-9 25mg $632 2018-11-13 Buy
Cayman Chemical 11334 Hypericin ≥95% 548-04-9 500μg $25 2018-11-19 Buy

Hypericin Chemical Properties,Uses,Production

Hypericum perforatum extracts

Hypericin is an extract of Hypericum perforatum L.In 1957. It is first isolated from the Garcinia species Hypericum perforatum by human beings. Hypericin belongs to the bianthrone compounds, and it is the most biologically active substances. Hypericin is a yellowish brown to brown mobile powder, with slightly bitter taste. It is soluble in water, and can emit a special fragrance. It can inhibit the central nervous and has a sedative effect. Adding it to health care products can enhance immunity. It is also used as antidepressant drugs in Europe (especially in Germany). Hypericin also has a strong anti-viral effect, which can directly act on swine fever, foot and mouth disease and other viruses. In addition, it also has a good effect on killing highly pathogenic avian influenza virus.
Hypericum perforatum is one of the world's best-selling herbs in recent years, mainly containing hyperoside, quercetin, chlorogenic acid, caffeic acid, imanin, hypericin and other ingredients.
Hypericin is a few thousandths of the whole Hypericum perforatum. There are certain requirements for its extraction and testing. Methanol extraction method is common used in the past. Due to the toxicity of methanol, now the method is   converted to use ethanol to obtain the active ingredient.

Indications

Hypericin is an anti-virus and pure Chinese medicine preparations. It is the first choice for the prevention and treatment of avian influenza drugs.
1, avian influenza, atypical Newcastle disease, infectious bronchitis, avian infectious laryngotracheitis , bursa of Fabricius, duck plague, duck viral hepatitis, egg drop syndrome and other viral diseases.
2, poultry fever caused by high fever, dyspnea, cough, head and face swelling, crown hair purple, lack of energy, decreased feed intake, egg drop, producing more abnormal eggs.
3, for classical swine fever, blue ear disease, parvovirus, viral enteritis, infectious gastroenteritis and immune dysfunction.
4, Hypericin has a strong anti-viral effect both in vivo and in vitro. It has a strong inhibitory effect on the early replication of HIV. Hypericin can lead to cancer cell programmed death, with anti-cancer effect. It has a enhanced immune function  for activating mononuclear phagocytic cells. In addition, it has a strong role in killing the highly pathogenic H5N1 and H9N2 subtype of avian influenza virus.

Uses

(1) Antidepressant, increase immunity.
(2) For the treatment of antidepressants, increase immunity.

Chemical Properties

Powder

Biological Activity

Photosensitive antiviral, anticancer and antidepressant agent derived from Hypericum perforatum (St John's wort). Inactivates enveloped viruses (including HIV), inhibits tyrosine kinases (IC 50 = 7.5 μ M) and is preferentially cytotoxic to tumor cells upon stimulation by visible light.

Purification Methods

Crystallise hypericin from pyridine by addition of methanolic HCl. [Beilstein 8 IV 3761.]

Hypericin Preparation Products And Raw materials

Raw materials

Preparation Products


Hypericin Suppliers

Global( 258)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2258 58
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21701 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
Zhenfei Industrial Co. Ltd.
+86 15318988277
sales@zhenfeichem.com CHINA 75 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29979 58
Zhejiang ZETian Fine Chemicals Co. LTD
+86-18957127338
sales@zetchem.com CHINA 1826 58
Chengdu GLP Biotech Co., Ltd
13350802083
scglp@glp-china.com CHINA 1007 58

View Lastest Price from Hypericin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-15 Hypericin
548-04-9
US $8.00 / kg 1kg 98% 100KG career henan chemical co
2019-06-27 Hypericin 548-04-9
548-04-9
US $650.00 / g 10mg ≥98% 1000.00 kgs NanJing Spring & Autumn Biological Engineering CO., LTD.
2018-11-16 Hypericin CAS NO.548-04-9
548-04-9
US $1.00 / G 1G 98% 2000KG Zhenfei Industrial Co. Ltd.

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