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Difluoroacetic acid

Difluoroacetic acid
Difluoroacetic acid structure
Chemical Name:
Difluoroacetic acid
DIFLUOROACETATE;VITAS-BB TBB000649;difluoro-aceticaci;DIFLUOROACETIC ACID;Difluoroaceticacid98%;Acetic acid, difluoro-;1,1-DIFLUOROACETIC ACID;2,2-DIFLUOROACETIC ACID;Twotrifluoroacetic acid;2,2-Difluoroethanoic acid
Molecular Formula:
Formula Weight:
MOL File:

Difluoroacetic acid Properties

Melting point:
-1 °C
Boiling point:
132-134 °C(lit.)
1.526 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.344(lit.)
Flash point:
174 °F
pK1:1.33 (25°C)
Clear colorless to light brown
Specific Gravity
1.527 (20℃)
CAS DataBase Reference
381-73-7(CAS DataBase Reference)
NIST Chemistry Reference
Difluoroacetic acid(381-73-7)
EPA Substance Registry System
Acetic acid, difluoro-(381-73-7)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  C
Risk Statements  34-35
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
RTECS  AG9900000
Hazard Note  Corrosive
HazardClass  8
PackingGroup  II
HS Code  29159080
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H290 May be corrosive to metals Corrosive to Metals Category 1 Warning P234, P390, P404
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P234 Keep only in original container.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P310 Immediately call a POISON CENTER or doctor/physician.
P390 Absorb spillage to prevent material damage.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P406 Store in corrosive resistant/… container with a resistant inner liner.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Difluoroacetic acid price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 142859 Difluoroacetic acid 98% 381-73-7 5g $56.3 2018-11-13 Buy
Sigma-Aldrich 142859 Difluoroacetic acid 98% 381-73-7 25g $197 2018-11-13 Buy
TCI Chemical D1423 Difluoroacetic Acid >97.0%(T) 381-73-7 5g $42 2018-11-22 Buy
TCI Chemical D1423 Difluoroacetic Acid >97.0%(T) 381-73-7 25g $126 2018-11-22 Buy
Alfa Aesar A12787 Difluoroacetic acid, 98% 381-73-7 25g $175 2018-11-13 Buy

Difluoroacetic acid Chemical Properties,Uses,Production

Chemical Properties

clear colorless to light brown liquid


ChEBI: A monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by fluorines.

Purification Methods

Purify the acid by distilling over P2O5. The acid chloride is a fuming liquid b 25o/atm, and the amide has b 108.6o/35mm, m 52o (from *C6H6), and the anilide has b 90o/1mm, 114o/5mm, m 58o [Henne & Pelley J Am Chem Soc 74 1426 1952, Coffman et al. J Org Chem 14 749 1949, NMR: Meyer et al. J Am Chem Soc 75 4567 1953, pK: Wegscheider Z Phys Chem 69 614 1909]. [Beilstein 2 IV 455.]

Difluoroacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Difluoroacetic acid Suppliers

Global( 196)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19919 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 21910 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 CHINA 2673 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 China 1752 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114 CHINA 6374 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 23982 58
Ji'nan Langhua Chemical Co. Ltd. +86-0531-85906691
+86-0531-85906692 China 101 50
Jinan LangHua Chemical Co., Ltd. +86-531-85906692
+86-531-85906692 China 216 58

View Lastest Price from Difluoroacetic acid manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-03-08 Difluoroacetic Acid
US $0.00 / L 200L 99% 1000MT Hefei TNJ Chemical Industry Co.,Ltd.

Difluoroacetic acid Spectrum

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