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PHORBOL 12,13-DIACETATE

CAS No.
24928-15-2
Chemical Name:
PHORBOL 12,13-DIACETATE
Synonyms
PDA;PHORBOL-DIACETATE;phorbol11,12-diacetate;phorbol10,11-diacetate;PHORBOL 12,13-DIACETATE;Phorbol 12,13-Diacetate >99%;PHORBOL 12,13-DIACETATE, 4BETA;l)-1,1,6,8-alpha-tetramethyl-,9,9a-diacetate,(+);8,9,9a-decahydro-4a-beta,7b-alpha,9-beta,9a-alpha-tetrahydroxy-3-(hydroxymethy;5h-cyclopropa(3,4)benz(1,2-e)azulen-5-one,1,1a-alpha,16-beta,4,4a,7a-alpha,7b,
CBNumber:
CB2702142
Molecular Formula:
C24H32O8
Molecular Weight:
448.51
MDL Number:
MFCD00036735
MOL File:
24928-15-2.mol
Last updated:2023-04-23 13:52:06

PHORBOL 12,13-DIACETATE Properties

Boiling point 477.23°C (rough estimate)
Density 1.1793 (rough estimate)
refractive index 1.4480 (estimate)
storage temp. −20°C
solubility H2O: soluble
form powder
color white
BRN 2317312

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300+H310+H330-H315-H319-H335
Precautionary statements  P262-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310-P305+P351+P338
Hazard Codes  T+
Risk Statements  26/27/28-36/37/38
Safety Statements  26-27-36/37/39-45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  GZ0651000
8-10
HazardClass  6.1(a)
PackingGroup  II
HS Code  2915290000

PHORBOL 12,13-DIACETATE price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AHH MT-21404 Phorbol 12,13-diacetate 95% 24928-15-2 0.01g $298 2021-12-16 Buy
Product number Packaging Price Buy
MT-21404 0.01g $298 Buy

PHORBOL 12,13-DIACETATE Chemical Properties,Uses,Production

Uses

Phorbol 12,13-diacetate may be used to stimulate protein kinase C (PKC) for phosphorylation of retinal proteins.

General Description

Phorbol ester with enhanced hydrophilicity.

Biochem/physiol Actions

Phorbol 12,13-diacetate (PDA) serves as a protein kinase C (PKC). It induces arrest in translocation in rod photoreceptors. PDA facilitates PKC in regulating airway contractility by inducing transient relaxation after a sustained contraction of the human isolated bronchus. PDA improves the synaptic transmission of nociceptive parabrachioamygdaloid (PBA) input onto neurons of the capsular central amygdaloid (CeAC) nucleus via activating PKC and extracellular-regulated kinase (ERK).

PHORBOL 12,13-DIACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

PHORBOL 12,13-DIACETATE Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Syntechem Co.,Ltd info@syntechem.com China 12990 57
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Phorbol 12,13-Diacetate >99% (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-(hydroxyMethyl)-1,1,6,8-tetraMethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulene-9,9a-diyl diacetate PHORBOL 12,13-DIACETATE PHORBOL 12,13-DIACETATE, 4BETA PDA 5h-cyclopropa(3,4)benz(1,2-e)azulen-5-one,1,1a-alpha,16-beta,4,4a,7a-alpha,7b, 8,9,9a-decahydro-4a-beta,7b-alpha,9-beta,9a-alpha-tetrahydroxy-3-(hydroxymethy l)-1,1,6,8-alpha-tetramethyl-,9,9a-diacetate,(+) phorbol10,11-diacetate phorbol11,12-diacetate PHORBOL-DIACETATE (1aR)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-Decahydro-5-oxo-3-(hydroxymethyl)-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulene-4aβ,7bα,9β,9aα-tetrol 9,9a-diacetate 5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 9,9a-bis(acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)- 24928-15-2 Cell Signaling and Neuroscience Cell Biology BioChemical Kinase/Phosphatase Biology Protein Kinase C (PKC) Serine/Threonine Kinase Activators Activator