ChemicalBook
Chinese Japanese Germany Korea

TRIOLEIN

TRIOLEIN
TRIOLEIN structure
CAS No.
122-32-7
Chemical Name:
TRIOLEIN
Synonyms
OLEIN;18:1TG;aldoto;raoline;TRIOLEIN;tri-olei;Erdnuoel;emery2423;TRIOLEINE;Radia 7363
CBNumber:
CB2715065
Molecular Formula:
C57H104O6
Formula Weight:
885.43
MOL File:
122-32-7.mol

TRIOLEIN Properties

Melting point:
-5,5°C
Boiling point:
235-240 °C18 mm Hg(lit.)
Density 
0.91 g/mL(lit.)
refractive index 
n20/D 1.470
Flash point:
330 °C
storage temp. 
2-8°C
solubility 
chloroform: 0.1 g/mL, clear, colorless
form 
Liquid
color 
Clear Pale Yellow
Merck 
14,9732
BRN 
1718692
Stability:
Stability Stable, but air and light sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference
122-32-7(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  F,Xn
Risk Statements  11-20/21/22-53
Safety Statements  24/25-39-26
RIDADR  UN 1282 3/PG 2
WGK Germany  -
RTECS  RG1936500
10-23
TSCA  Yes
HS Code  29161500
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

TRIOLEIN price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 92860 Glyceryl trioleate ≥97.0% (TLC) 122-32-7 5ml $73.5 2018-11-13 Buy
Sigma-Aldrich 41679 Glyceryl trioleate analytical standard 122-32-7 100mg $74.7 2018-11-13 Buy
TCI Chemical G0089 Triolein >80.0%(GC) 122-32-7 25g $87 2018-11-22 Buy
TCI Chemical G0089 Triolein >80.0%(GC) 122-32-7 100g $220 2018-11-22 Buy
Alfa Aesar J62419 Triolein, tech. 75% 122-32-7 100g $366 2018-11-13 Buy

TRIOLEIN Chemical Properties,Uses,Production

Chemical Properties

colourless viscous liquid

Chemical Properties

Triolein occurs as a clear, colorless to yellowish oily liquid, and is tasteless and odorless.

Definition

ChEBI: A triglyceride formed by esterification of the three hydroxy groups of glycerol with oleic acid. Triolein is one of the two components of Lorenzo's oil.

Production Methods

Triolein is manufactured by the esterification of fractionated fatty acids, mainly oleic acid and glycerin.

Pharmaceutical Applications

Triolein is used as a solubilizer and solvent in injectable preparations. It has been used in marketed preparations of sustained-release injections of cytarabine and multivesicular liposomal injections of morphine sulfate. It has also been used in enteric coatings for oral preparations in combination with other enteric coating excipients to protect against degradation by pancreatic lipase.
Triolen is used in personal care products as a skin-conditioning and viscosity-controlling agent.

Safety

Triolein is used in injectable preparations, in enteric coatings for oral preparations, and in personal care products. Chronic exposure may cause nausea and vomiting, and higher exposures may cause unconsciousness.
The Cosmetic Ingredient Review (CIR) Expert Panel found that dermal application of triolein was not associated with significant irritation, and no evidence of sensitization or photosensitization was observed. Ocular exposures were found to be only mildly irritating to eyes. Triolein has not been found to be genotoxic in a number of in vitro and in vitro assay systems. Subcutaneous injections of triolein in rats showed no tumors at the injection site. The CIR Expert Panel also noted that metabolism data indicated that glyceryl triesters (including triolein) followed the same metabolic pathways as fats in food. They were split into monoglycerides, free fatty acids, and glycerol, all of which were absorbed into the intestinal mucosa and metabolized further. Therefore, oral exposure to these compounds was not found to be a concern.
A triolein-based amphotericin emulsion showed better safety with a higher LD50 in rats as compared with the conventional amphotericin deoxycholate.

storage

Triolein is classified as a stable compound but is sensitive to air and light. It should be stored in tightly sealed containers in a dry area at 2–8℃. Thermal decomposition of triolein may lead to release of irritating gases and vapors such as carbon oxides. Exposure to air and moisture over prolonged periods should be avoided.

Incompatibilities

Triolein is incompatible with strong oxidizing agents and spontaneously flammable products. Being a triglyceride ester, triolein can be hydrolyzed by strong acids, and particularly by strong bases. It is possible for primary amines to form an adduct across the olefinic double bonds (analogous to a Michael addition).

Regulatory Status

Included in the FDA Inactive Ingredients Database (liposomal suspension for epidural injections). Included in parenteral medicines (suspension for intrathecal injection) licensed in the UK.
Triolein is included in the CIR category as safe for use in cosmetics and personal care products. Its use as an indirect food additive has been approved by the FDA.

TRIOLEIN Preparation Products And Raw materials

Raw materials

Preparation Products


TRIOLEIN Suppliers

Global( 181)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 27142 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2995 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23967 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8260 58
Shaanxi Pioneer Biotech Co., Ltd .
86-13259417953(Whatsapp)
029-84385017 sales@pioneerbiotech.com CHINA 3031 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20115 58

View Lastest Price from TRIOLEIN manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-24 TRIOLEIN
122-32-7
US $1.00 / KG 1g 99% 100KG career henan chemical co

TRIOLEIN Spectrum


122-32-7(TRIOLEIN)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved