Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Eptaplatin

Eptaplatin

Eptaplatin Structure
Eptaplatin structure
CAS No.
146665-77-2
Chemical Name:
Eptaplatin
Synonyms
SUNPLA;SKI 2053R;EPTAPLATIN;heptaplatin;(SP-4-2)-[(4R,5R;EPOXYPROGESTERONE;Eptaplatin, >=98%;EPTAPLATIN, SUNPLA;Eptaplatin(SKI-2053R);Eptaplatin(Heptaplatin)
CBNumber:
CB2717771
Molecular Formula:
C11H20N2O6Pt
Molecular Weight:
471.36
MDL Number:
MFCD00931412
MOL File:
146665-77-2.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06
Request For Quotation

Eptaplatin Properties

Melting point 43-49°C
storage temp. Refrigerator, Under Inert Atmosphere
solubility DMSO (Slightly), Water (Slightly, Heated)
form Solid
color White to Off-White
FDA UNII 1352HON1DH

Eptaplatin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E591500 Eptaplatin 146665-77-2 50mg $910 2021-12-16 Buy
American Custom Chemicals Corporation API0002576 EPTAPLATIN 95.00% 146665-77-2 0.025G $1044 2021-12-16 Buy
Biosynth Carbosynth FE22772 Eptaplatin 146665-77-2 10mg $95 2021-12-16 Buy
AK Scientific N771 Eptaplatin 146665-77-2 5mg $158 2021-12-16 Buy
Biosynth Carbosynth FE22772 Eptaplatin 146665-77-2 50mg $333 2021-12-16 Buy
Product number Packaging Price Buy
E591500 50mg $910 Buy
API0002576 0.025G $1044 Buy
FE22772 10mg $95 Buy
N771 5mg $158 Buy
FE22772 50mg $333 Buy

Eptaplatin Chemical Properties,Uses,Production

Description

SKI-2053R was launched in Korea for the treatment of patients with advanced gastric adenocarcinoma. It is a third generation platinum complex alkylating agent with less nephrotoxicity than cisplatin. In in vitro experiments, SKI-2053R was highly active against various cell lines including cisplatinresistant tumor cell lines. In mice implanted with L1210 cells, SKI-2053R showed activity comparable or superior to cisplatin or carboplatin. In mice implanted s.c. with human tumor xenograft KATO III (stomach adenocarcinoma), SKI-2053R achieved growth-inhibition rates comparable with those of cisplatin. General pharmacological studies in animals did not display any severe adverse effects on the different systems at antitumour doses. Pharmacokinetic studies after a single iv administration in rats demonstrated that the compound was extensively and rapidly distributed into all tissues except the CNS. In patients with unresectable or metastatic gastric adenocarcinoma, SKI-2053R was active without significant hematological toxicity. Phase III trials with SKI-2053R are currently ongoing for the treatment of various other cancers including lung, head and neck.

Chemical Properties

White Crystalline Powder

Originator

SK Pharma (Korea)

Uses

A coordination compound for treatment of cervix cancer.

brand name

Sunpla

Pharmaceutical Applications

heptaplatin is further examples of platinum-based agents being used in China and South Korea, respectively. Heptaplatin is used in South Korea to treat gastric cancer. It show the typical side effects such as myelosuppression and mild hepatotoxicity. its success is limited and has not led to approval in the EU or by the FDA.

Eptaplatin Preparation Products And Raw materials

Raw materials

Preparation Products

Eptaplatin Suppliers

Global( 86)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10828 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuhan Fortuna Chemical Co., Ltd 		+86-27-59207850 +86-13986145403 info@fortunachem.com China 5985 58
Baoji Guokang Bio-Technology Co., Ltd. 		0917-3909592 13892490616 gksales1@gk-bio.com China 9339 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Hebei Duling International Trade Co. LTD 		+8618032673083 sales05@hbduling.cn China 15747 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49999 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Supplier Advantage
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
Wuhan Fortuna Chemical Co., Ltd 		58
Baoji Guokang Bio-Technology Co., Ltd. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Hebei Duling International Trade Co. LTD 		58
GIHI CHEMICALS CO.,LIMITED 		58
Aladdin Scientific 		58

View Lastest Price from Eptaplatin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Eptaplatin pictures 2022-12-30 Eptaplatin
146665-77-2
 US $0.00 / g 1g 98%-102% 100g WUHAN FORTUNA CHEMICAL CO., LTD
Eptaplatin pictures 2021-07-13 Eptaplatin
146665-77-2
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
Eptaplatin pictures 2021-07-09 Eptaplatin
146665-77-2
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • Eptaplatin pictures
  • Eptaplatin
    146665-77-2
  • US $0.00 / g
  • 98%-102%
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Eptaplatin pictures
  • Eptaplatin
    146665-77-2
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • Eptaplatin pictures
  • Eptaplatin
    146665-77-2
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd

146665-77-2(Eptaplatin)Related Search:

Cisplatin Carboplatin cis-Diamminediiodoplatinum Nedaplatin LOBAPLATIN
DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Picoplatin Satraplatin (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate DIBROMO(1,5-CYCLOOCTADIENE)PLATINUM(II)
Platinum Malonic acid (4R,5R)-4,5-BIS(AMINOMETHYL)-2-ISOPROPYL-1,3-DIOXOLANE Eptaplatin

1of3

SUNPLA [sp-4-2-[4r-(2a,4a,5b)]]-[2-(1-methylethyl)-1,3-dioxolane-4,5-dimethanamine-n,n'][propanedioato(2-)-o,o']-platinum heptaplatin EPTAPLATIN SKI 2053R EPOXYPROGESTERONE (SP-4-2)-[(4R,5R)-2-ISOPROPYL-1,3-DIOXOLANE-4,5-BIS(METHANAMINE)-N,N''][PROPANEDIOATO(2-)-O,O'']PLATINUM (SP-4-2)-[(4R,5R)-2-(1-Methylethyl-1,3-dioxolane 4,5-dimethanamine-kN4,kN5][propanedioato(2-)-kO1,kO3]platinum cis-[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane](malonate)platinum(II) (SP-4-2)-[(4R,5R)-2-Isopropyl-1,3-dioxolane-4,5- EPTAPLATIN, SUNPLA Eptaplatin(Heptaplatin) Eptaplatin(SKI-2053R) Eptaplatin, >=98% (SP-4-2)-[(4R,5R cis-[(4R,5R)-2-Isopropyl-1,3-dioxolane-4,5-bis(methylamine)-N,N'][malonato(2-)-O,O']platinum Cis-(1,3-malanato)-[(4R,5R)-4,5-bis(aminomethyl)-2isopropyl-1,3-dioxolane]platinum(II) cis-{Pt(II)[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane](3-acetoxyl-cyclobutane-1,1-dicarboxylato)} 9-propan-2-yl-8,10-dioxa-3,5-diaza-4$l^{4}-platinabicyclo[5.3.0]deca-3,4-diene cis-[2-Isopropyl-1,3-dioxolane-4,5-bis(methylamine)-N,N][malonato(2-)-O,O]platinum Heptaplatin (SKI-2053R) 146665-77-2 C11H20N2O6Pt C8H18N2O2C3H2O4Pt C11H16N2O6Pt Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Heterocyclic Compounds Anticancer