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Citalopram hydrobromide

Abstract Efficacy Side effects References
Citalopram hydrobromide
Citalopram hydrobromide structure
CAS No.
59729-32-7
Chemical Name:
Citalopram hydrobromide
Synonyms
ERDOSTEIN;CITALOPRAM HBR;Citalopran HBr;Citalopram-D4Br;CitalopraM HBr API;Citalopram HBr Salt;CITALOPRAM HYDROBROMIDE;Citalopramehydrobromide;CITALOPRAM BROMOHYDRATE;Citaloplam hydrobromide
CBNumber:
CB2736240
Molecular Formula:
C20H22BrFN2O
Formula Weight:
405.3
MOL File:
59729-32-7.mol

Citalopram hydrobromide Properties

Melting point:
182-188°C
Flash point:
9℃
storage temp. 
-20°C Freezer
solubility 
H2O: soluble (sparingly)
form 
powder
Merck 
14,2318
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
59729-32-7(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25-22
Safety Statements  7-16-36/37-45-24/25
RIDADR  3249
WGK Germany  3
RTECS  NP6313500
HazardClass  6.1(b)
PackingGroup  III
HS Code  29329990
Hazardous Substances Data 59729-32-7(Hazardous Substances Data)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P311 Call a POISON CENTER or doctor/physician.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Citalopram hydrobromide price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C-057 Citalopram hydrobromide solution 59729-32-7 057-1ml $52 2018-11-20 Buy
Sigma-Aldrich 1134233 Citalopram hydrobromide United States Pharmacopeia (USP) Reference Standard 59729-32-7 200mg $696 2018-11-13 Buy
TCI Chemical C2370 Citalopram Hydrobromide >98.0%(HPLC)(T) 59729-32-7 1g $89 2018-11-22 Buy
TCI Chemical C2370 Citalopram Hydrobromide >98.0%(HPLC)(T) 59729-32-7 5g $306 2018-11-22 Buy
Cayman Chemical 14572 Citalopram (hydrobromide) ≥98% 59729-32-7 1g $945 2018-11-13 Buy

Citalopram hydrobromide Chemical Properties,Uses,Production

Abstract

Citalopram hydrobromide (citalopram HBr) is an orally administered selective serotonin reuptake inhibitor (SSRI) with a chemical structure unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other available antidepressant agents.
Citalopram HBr occurs as a fine, white to off-white powder. Citalopram HBr is sparingly soluble in water and soluble in ethanol.
The tablet is available as the brand-name drug Celexa. In Australia, the UK, Germany, Portugal, Poland, and most European countries, it is licensed for depressive episodes and panic disorder with or without agoraphobia. In Spain, it is also used for obsessive-compulsive disorder.

Efficacy

The advantage of this drug is that it has no effect on cholinergic muscarinic receptors, histamine receptors and α-adrenergic receptors . Because if these receptors are inhibited,  a lot of side effects caused by antidepressants will produce, such as dry mouth, sedation, orthostatic hypotension. Citalopram hydrobromide is effective for not only endogenous depression patients but also non-endogenous depression patients. Its antidepressant effect is usually established after 2-4 weeks . Citalopram hydrobromide does not affect the cardiac conduction system and blood pressure, which is particularly important for elderly patients. In addition, citalopram hydrobromide does not affect the blood, liver and kidney systems. Rare side effects and the most mild sedative properties make it particularly suitable for long-term treatment.It does not lead to weight gaining,and it does not strengthen the role of alcohol.

Side effects

You should not use this medicine if you are allergic to citalopram or escitalopram (Lexapro), or if you also take pimozide.
Do not use citalopram if you have used an monoamine oxidase inhibitor (MAOI) in the past 14 days. A dangerous drug interaction could occur. MAOI inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Side effects are usually small, very mild and transient. The most common adverse reactions are: nausea, increased sweating, salivation reduction, headaches and sleep time shortening. They are usually more obvious in the first or second week when treatment begins, and they generally disappear with the improvement of depression. In rare cases ,seizures have been observed. For  patients who suffer bradycardia , bradycardia can make treatment more complicated.

References

http://www.rxlist.com/celexa-drug.htm
https://en.wikipedia.org/wiki/Citalopram
https://www.drugs.com/citalopram.html

Chemical Properties

White or almost white, crystalline powder.

Uses

Antidepressant;5HT uptake inhibitor

Uses

Anti-depressant/Anti-psychotic

Uses

An inhibitor of serotonin (5-HT) uptake. Used as an antidepressant

brand name

Celexa (Forest).

Hazard

A poison.

Biological Activity

Potent and selective serotonin uptake inhibitor (Ki=5.4nM). Modifies gene expression profile in Alzheimer lymphocytes. Clinically useful antidepressant.

Citalopram hydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products


Citalopram hydrobromide Suppliers

Global( 244)Suppliers
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Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan DaKen Chemical CO.,LTD.
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Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
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Henan Tianfu Chemical Co.,Ltd.
0371-55170693
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Mainchem Co., Ltd.
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career henan chemical co
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Jinan Jianfeng Chemical Co., Ltd
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Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8260 58

View Lastest Price from Citalopram hydrobromide manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-08-02 Citalopram hydrobromide
59729-32-7
US $7.00 / KG 1KG 99% 100kg career henan chemical co

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