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4-Mercaptopyridine

4-Mercaptopyridine structure

CAS No.: 4556-23-4

Chemical Name:: 4-Mercaptopyridine

Synonyms: NOLA-009;NSC 76036;4-Thiopyridine;4-PYRIDINETHIOL;4-Pyridimethiol;Pyridine-4-thiol;Mercaptopyridine;4-Mecaptopyridine;4-mercatopyridine;4-Sulfanylpyridine

CBNumber:: CB2748207

Molecular Formula:: C5H5NS

Molecular Weight:: 111.16

MDL Number:: MFCD00006422

MOL File:: 4556-23-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:59:15

Product description	Number	Pack Size	Price
4-Mercaptopyridine 95%	148202	1g	$50.3
4-Mercaptopyridine 95%	148202	10g	$237
4-Mercaptopyridine >97.0%(T)	M0630	5g	$88
4-Mercaptopyridine >97.0%(T)	M0630	25g	$240
4-Mercaptopyridine	M225500	1g	$45
More product size

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4-Mercaptopyridine Properties

Melting point	182-189 °C
Boiling point	194.0±13.0 °C(Predicted)
Density	1.161 (estimate)
refractive index	1.5605 (estimate)
storage temp.	2-8°C
solubility	DMSO, Methanol
pka	pK1:1.43(＋1);pK2:8.86(0) (20°C)
form	Crystalline Powder
color	Yellow to yellow-green or brown
InChI	InChI=1S/C5H5NS/c7-5-1-3-6-4-2-5/h1-4H,(H,6,7)
InChIKey	FHTDDANQIMVWKZ-UHFFFAOYSA-N
SMILES	C1=NC=CC(S)=C1
CAS DataBase Reference	4556-23-4(CAS DataBase Reference)
EWG's Food Scores	1
NIST Chemistry Reference	4-Pyridinethiol(4556-23-4)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-37/39-24/25

WGK Germany

RTECS

UT8578000

HS Code

29333990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		0

4-Mercaptopyridine price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	148202	4-Mercaptopyridine 95%	4556-23-4	1g	$50.3	2026-04-30	Buy
Sigma-Aldrich	148202	4-Mercaptopyridine 95%	4556-23-4	10g	$237	2026-04-30	Buy
TCI Chemical	M0630	4-Mercaptopyridine >97.0%(T)	4556-23-4	5g	$88	2026-04-30	Buy
TCI Chemical	M0630	4-Mercaptopyridine >97.0%(T)	4556-23-4	25g	$240	2026-04-30	Buy
TRC	M225500	4-Mercaptopyridine	4556-23-4	1g	$45	2021-12-16	Buy

Product number	Packaging	Price	Buy
148202	1g	$50.3	Buy
148202	10g	$237	Buy
M0630	5g	$88	Buy
M0630	25g	$240	Buy
M225500	1g	$45	Buy

4-Mercaptopyridine Chemical Properties,Uses,Production

Chemical Properties

4-Mercaptopyridine is Yellow to light yellow crystalline powder

Uses

4-Mercaptopyridine is a pyridine derivative used as a redox reagents for the in vitro refolding of a recombinantly expressed single-chain Fv fragment (scFvOx). Used in studies along with thiosulfate to measure alliinase activity.

Uses

mercaptopyridine is also known as sodium pyrithione. It is a preservative that is not commoly used.

Uses

4-Mercaptopyridine was used as a probe molecule to study the performance of the gold nanorod (AuNR)/polycaprolactone (PCL) fibrous mesh.

Purification Methods

Purify the thiol by dissolving ~45g in boiling H2O (100mL) (charcoal), filter and precipitate it by adding 50% aqueous NaOH (~80mL) to pH ~6. Dissolve the precipitate in EtOH, evaporate it to dryness, then crystallise it from boiling EtOH (~100mL, charcoal) to give yellow flat hexagonal plates (m 186o). It sublimes readily in vacuo. [King & Ware J Chem Soc 873 1939.] The picrate forms yellow needles from H2O with m 222o(dec). The 4-methylmercaptopyridine derivative crystallises from pet ether (m 47o , also 44-45o was reported, with a pK2 0 of 5.97) and was prepared by treatment with MeI/NaOH. Its picrate has m 2 4 5o (from H2O, MeOH or EtOH). The N-methyl-4-pyridinethiol derivative has m 168.5-170o (from EtOH), a pK2 0 of 1.30 and is soluble in CHCl3. [Albert & Barlin J Chem Soc 2384 1959, Beilstein 21 II 35, 22 III/IV 373, 22/7 V 147.]

4-Mercaptopyridine synthesis

Synthesis of 4-Mercaptopyridine from 4-chloropyridine and Carbamimidothioic acid

4-Mercaptopyridine Preparation Products And Raw materials

Raw materials

4-chloropyridine Carbamimidothioic acid

Preparation Products

S-METHYL-S-(4-PYRIDINYL) SULFOXIMINE 4,4'-DIPYRIDYL SULFIDE

4-Mercaptopyridine Suppliers

Global( 275)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Hebei shuoxi biotechnology co. LTD	+8613081092107		CHINA	964	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Hebei Binshare New Material Co. Ltd	+8618633865755	china01@hbbinshare.com	CHINA	955	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14304	58
Wuhan Fortuna Chemical Co., Ltd	+86-27-59207850	info@fortunachem.com	China	5974	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Hebei shuoxi biotechnology co. LTD	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58
SIMAGCHEM CORP	58
Hebei Binshare New Material Co. Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Win-Win chemical CO., Limited	58
Wuhan Fortuna Chemical Co., Ltd	58

View Lastest Price from 4-Mercaptopyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-30	4-Mercaptopyridine 4556-23-4	US $0.00 / Kg/Drum	1KG	98%min	1000kgs	WUHAN FORTUNA CHEMICAL CO., LTD
2021-07-02	4-Mercaptopyridine 4556-23-4	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-03-17	4-pyridinethiol 4556-23-4	US $90.00 / g	10g	99.8%	10tons	Hebei shuoxi biotechnology co. LTD

4-Mercaptopyridine
4556-23-4
US $0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

4-Mercaptopyridine
4556-23-4
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

4-pyridinethiol
4556-23-4
US $90.00 / g
99.8%
Hebei shuoxi biotechnology co. LTD

4-Mercaptopyridine Spectrum

4-Mercaptopyridine(4556-23-4)IR1 4-Mercaptopyridine(4556-23-4)Raman

4556-23-4(4-Mercaptopyridine)Related Search:

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4-PYRIDINETHIOL 4-PYRIDYL MERCAPTAN 4-MERCAPTOPYRIDINE Pyridine-4-thiol 4-Mercaptopyridine, 96% 10GR 4-Mercaptopyridine, 96% 1GR Pyridine-4-thiol, 4-Mercaptopyridine, 4-Sulphanylpyridine Mercaptopyridine 4-Sulfanylpyridine NSC 76036 4-Pyridinethiol 4-Pyridyl Mercaptan 4-Mecaptopyridine 4-Thiopyridine Pyridine, 4-mercapto- Mercaptopyridine,90% 4-Pyridimethiol 4-mercapto-pyridin 4-mercatopyridine 1H-Pyridine-4-thione 4-Mercaptopyridine,96% 4-Mercaptopyridine,4-Pyridinethiol 4-Mercaptopyridine, 97.0%(T) NOLA-009 4-Mercaptopyridine> Pyridine-4-thiol - [M28454] 4556-23-4 C5H4NS Pyridines Heterocyclic Building Blocks Building Blocks C5 Building Blocks C5 Chemical Synthesis Heterocyclic Building Blocks Pyridines Pyridine Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds bc0001