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Methylene Blue

Methylene Blue
Methylene Blue structure
CAS No.
61-73-4
Chemical Name:
Methylene Blue
Synonyms
CI 52015;S NO 1038;SWISS BLUE;Chromosmon;Nsc 617593;D&CBLUENO.1;CI NO 52015;BASIC BLUE 9;Schultz 1038;Urolene Blue
CBNumber:
CB2748858
Molecular Formula:
C16H18ClN3S
Formula Weight:
319.85
MOL File:
61-73-4.mol

Methylene Blue Properties

Melting point:
190 °C (dec.)(lit.)
Density 
1.0 g/mL at 20 °C
refractive index 
n20/D1.347
Flash point:
45 °C
storage temp. 
Store at RT
solubility 
Soluble in water, ethanol, ethylene glycol, methyl cellosolve
Colour Index 
52015
form 
Liquid
pka
2.6, 11.2(at 25℃)
color 
Green
Specific Gravity
0.98
Water Solubility 
40 g/L (20 ºC)
λmax
661 nm
Merck 
14,6060
BRN 
3641570
Biological Applications
Detecting microorganisms; treating diabetic retinopathy,macular degeneration,malignant uveal melanomas,erysipelas,hidradenitis suppurativa,inflammation,skin diseases
NIST Chemistry Reference
Methylene blue(61-73-4)
EPA Substance Registry System
Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride(61-73-4)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  10-41-22-20/21/22-36/37/38
Safety Statements  26-39-36
RIDADR  UN 1993 3/PG 3
WGK Germany  3
RTECS  SP5740000
HS Code  32049010
Hazardous Substances Data 61-73-4(Hazardous Substances Data)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
Precautionary statements:
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.

Methylene Blue price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 03978 Methylene Blue solution 61-73-4 250ml $39.5 2018-11-22 Buy
Sigma-Aldrich 284-M Methylene Blue solution alkaline according to Loeffler 61-73-4 12 $83.9 2018-11-20 Buy
TCI Chemical A5105 Methylene Blue [Ion association reagent for spectrophotometric analysis] >98.0%(T) 61-73-4 1g $40 2018-11-22 Buy
TCI Chemical M0501 Methylene Blue Hydrate >70.0%(W) 61-73-4 25g $25 2018-11-22 Buy
Sigma-Aldrich 457250 Methylene Blue Inhibitor of soluble guanylate cyclase. 61-73-4 1gm $42.5 2018-11-20 Buy

Methylene Blue Chemical Properties,Uses,Production

Chemical Properties

green fine crystalline powder

Uses

A useful inhibitor of cGMP-mediated processes and a useful stain

Definition

ChEBI: An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties.

Hazard

Toxic by ingestion.

Biological Activity

Biological stain and redox indicator. Inhibits tau filament formation (IC 50 = 1.9 μ M). Also inhibits soluble guanylyl cyclase.

Clinical Use

Methylene blue is 3,7-bis(dimethylamino)-phenazathioniumchloride (Urised). The compound occurs as a dark greencrystalline powder with a metallic appearance that is solublein water (1:25) and alcohol (1:65).
Methylene blue has weak antiseptic properties that makeit useful for the treatment of cystitis and urethritis. The actionof methylene blue is considered to be bacteriostatic.The compound colors the urine and stool blue green.

Purification Methods

Crystallise the chloride from 0.1M 664 2HCl (16mL/g), the crystals are separated by centrifugation, washed with chilled EtOH and diethyl ether, and dried under vacuum. Crystallise it from 50% aqueous EtOH, wash it with absolute EtOH, and dry it at 50-55o for 24hours. It has also been crystallised from *benzene/MeOH (3:1). It has been salted out with NaCl from a commercial concentrated aqueous solution, then crystallised from water, and dried at 100o in an oven for 8-10hours. [Beilstein 27 III/IV 5152.]

Methylene Blue Preparation Products And Raw materials

Raw materials

Preparation Products


Methylene Blue Suppliers

Global( 164)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21990 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1730 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20095 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 4669 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19923 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40277 62

View Lastest Price from Methylene Blue manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-22 Methylene Blue
61-73-4
US $1.00 / kg 1kg 99% C16H18ClN3S career henan chemical co

Methylene Blue Spectrum


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