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4-Bromo-2-fluoroaniline

4-Bromo-2-fluoroaniline Structure
4-Bromo-2-fluoroaniline structure
CAS No.
367-24-8
Chemical Name:
4-Bromo-2-fluoroaniline
Synonyms
2-Fluoro-4-Bromoaniline;4-BROMO-2-FLUORO-PHENYLAMINE;4-Bromo-2-fL;AKOS BBS-00003609;Bromofluoroaniline4;4-Bromo-2-fluoroanil;4-Brom-2-fluoranilin;Fluoro-4-bromoaniline;Vandetanib Impurity 2;4-BROMO-2-FLUOROANILINE
CBNumber:
CB2765000
Molecular Formula:
C6H5BrFN
Molecular Weight:
190.01
MDL Number:
MFCD00010221
MOL File:
367-24-8.mol
MSDS File:
SDS
Last updated:2024-03-28 10:29:10
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4-Bromo-2-fluoroaniline Properties

Melting point 40-42 °C
Boiling point 103-108 °C (13 mmHg)
Density 1.6196 (rough estimate)
refractive index 1.4710 (estimate)
Flash point 220 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 2.50±0.10(Predicted)
form Crystalline Mass, Powder, Crystals and/or Chunks
color Beige to light brown to brown-gray or gray
BRN 2081089
Stability Stable. Incompatible with acid chlorides, acid anhydrides, strong acids, strong oxidizing agents.
InChI InChI=1S/C6H5BrFN/c7-4-1-2-6(9)5(8)3-4/h1-3H,9H2
InChIKey GZRMNMGWNKSANY-UHFFFAOYSA-N
SMILES C1(N)=CC=C(Br)C=C1F
CAS DataBase Reference 367-24-8(CAS DataBase Reference)
NIST Chemistry Reference 4-Bromo-2-fluoroaniline(367-24-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,T,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-37/39-36/37/39-36
RIDADR  UN2811
WGK Germany  3
Hazard Note  Toxic
HazardClass  6.1
PackingGroup  III
HS Code  29214200
NFPA 704
0
2 0

4-Bromo-2-fluoroaniline price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 304220 4-Bromo-2-fluoroaniline 98% 367-24-8 10g $47.2 2024-03-01 Buy
Sigma-Aldrich 304220 4-Bromo-2-fluoroaniline 98% 367-24-8 50g $64.2 2024-03-01 Buy
TCI Chemical B1314 4-Bromo-2-fluoroaniline >98.0%(GC)(T) 367-24-8 25g $72 2024-03-01 Buy
Alfa Aesar A10228 4-Bromo-2-fluoroaniline, 98+% 367-24-8 10g $20.65 2024-03-01 Buy
Alfa Aesar A10228 4-Bromo-2-fluoroaniline, 98+% 367-24-8 25g $39.65 2024-03-01 Buy
Product number Packaging Price Buy
304220 10g $47.2 Buy
304220 50g $64.2 Buy
B1314 25g $72 Buy
A10228 10g $20.65 Buy
A10228 25g $39.65 Buy

4-Bromo-2-fluoroaniline Chemical Properties,Uses,Production

Chemical Properties

solid

Uses

4-Bromo-2-fluoroaniline was used in synthesis of 4-amino-3-fluorophenyl boronic acid. It was also used in chemical modification and synthesis of boronic acid derivatives for ultraviolet-visible titration.

Uses

4-Bromo-2-fluoroaniline can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis

Synthesis_367-24-8
To a stirred solution of 4-bromo-2-fluoro-l -nitrobenzene (10 g, 45.5 mmol) in EtOH (50 mL)AVater (20 mL) was added iron (12.7 g, 230 mmol) and NH4C1 (24.3 g, 455 mmol). The reaction mixture was stirred at 90 ??C for 2 h. After 2 h the reaction mixture was filtered over Celite. The filter cake was washed with EtOH (300 mL), and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel chromatography (S1O2, Petroleum ether/EtOAc=10: l to 5: 1) to afford 4-bromo-2-fluoroaniline.

4-Bromo-2-fluoroaniline synthesis

348-54-9
367-24-8
141474-37-5
Synthesis of 4-Bromo-2-fluoroaniline from 2-Fluoroaniline

4-Bromo-2-fluoroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

2-Fluoro-4-(methylsulfonyl)aniline 4'-Bromo-2'-fluoroacetanilide 6-Bromo-7-fluoroquinoline 4-acetyl-3-fluorobenzonitrile 7-Bromo-4-methyl-2H-1,4-benzoxazin-3-one
4-BROMO-2-FLUOROPHENYLISOTHIOCYANATE 96 N-(4-bromo-2-fluorophenyl)-2-phenylbutanamide N-(4-bromo-2-fluorophenyl)-4-fluorobenzamide 7-(benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine

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4-Bromo-2-fluoroaniline Suppliers

Global( 575)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhejiang Kinso Pharmaceuticals Co., LTD. 		+8619857958369 sales@kinsopharma.com China 27 58
Allfluoro pharmaceutical co. ltd.
021-26137118 +8615821363818 sales@allfluoro.com China 5791 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12453 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5993 58
Hebei Guanlang Biotechnology Co,.LTD 		+8619930503252 daisy@crovellbio.com China 5964 58
Anhui Ruihan Technology Co., Ltd 		+8617756083858 daisy@anhuiruihan.com China 994 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7377 58
Frapp's ChemicalNFTZ Co., Ltd. 		+86 (576) 8169-6106 sales@frappschem.com China 885 50
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Hi-Tech Chemistry Corp 		0519-86626038 yuhh@hitechem.com CHINA 811 58
Supplier Advantage
Zhejiang Kinso Pharmaceuticals Co., LTD. 		58
Allfluoro pharmaceutical co. ltd.
58
Hebei Mojin Biotechnology Co., Ltd 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Guanlang Biotechnology Co,.LTD 		58
Anhui Ruihan Technology Co., Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Frapp's ChemicalNFTZ Co., Ltd. 		50
Capot Chemical Co.,Ltd. 		60
Hi-Tech Chemistry Corp 		58

View Lastest Price from 4-Bromo-2-fluoroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Bromo-2-fluoroaniline pictures 2024-01-22 4-Bromo-2-fluoroaniline
367-24-8
 US $8.00-0.80 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-Bromo-2-fluoroaniline pictures 2023-12-29 4-Bromo-2-fluoroaniline
367-24-8
 US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
4-Bromo-2-fluoroaniline pictures 2023-09-26 4-Bromo-2-fluoroaniline
367-24-8
 US $80.00-20.00 / kgkg 1kgkg 0.99 10000 Hebei Yanxi Chemical Co., Ltd.

4-Bromo-2-fluoroaniline Spectrum

4-Bromo-2-fluoroaniline(367-24-8)MS4-Bromo-2-fluoroaniline(367-24-8)1HNMR4-Bromo-2-fluoroaniline(367-24-8)IR14-Bromo-2-fluoroaniline(367-24-8)IR24-Bromo-2-fluoroaniline(367-24-8)Raman

367-24-8(4-Bromo-2-fluoroaniline)Related Search:

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4-BROMO-2,5-DIFLUORONITROBENZENE 4-BROMO-2-FLUOROPHENYL ISOCYANATE 4'-Bromo-2'-fluoroacetanilide 2,4-DIBROMO-6-FLUOROANILINE Vandetanib
2,6-Dibromo-4-fluoroaniline 2-Bromo-4-fluoroaniline99%,2-Bromo-4-fluoroaniline 99%,2-BROMO-4-FLUOROANILINE 98+%,2-BROMO-4-FLUOROANILINE Bromine

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Benzenamine, 4-bromo-2-fluoro- AKOS BBS-00003609 4-Bromo-2-fluoroaniline 99% 4-Bromo-2-fluoroaniline99% Bromofluoroaniline4 -BROMO-2-FLUOROANILINE, 98% 4-Bromo-2-fluoroaniline,98+% 4-BROMO-2-FLUOROANILINE 4-bromo-2-fluoro-Benzenamine 4-Bromo-2-fluoroanil 4-BroMo-2-fluoroaniline, 99% 10GR 4-BroMo-o-fluoroaniline o-fluoro-4-broMoaniline 4 - broMine - 2 - fluoro aniline Fluoro-4-bromoaniline 4-Bromo-2-fL 4-Brom-2-fluoranilin 4-Bromo-2-fluoroaniline > 4-Bromo-2-fluoroaniline ISO 9001：2015 REACH Vandetanib Impurity 2 2-Fluoro-4-Bromoaniline 4-BROMO-2-FLUORO-PHENYLAMINE 4- Bromo 2- Fluoro aniline [ 4-B2FA] 367-24-8 367-42-8 C2 to C6 Amines Building Blocks Nitrogen Compounds Organic Building Blocks Trifluoromethoxybenzene Series Anilines, Amides & Amines Bromine Compounds Fluorine Compounds Amines C2 to C6 Nitrogen Compounds Fluorobenzene Fluoro-Aromatics PHARMACEUTICAL INTERMEDIATES Anilines, Aromatic Amines and Nitro Compounds Aniline amine| alkyl Fluorine| alkyl bromide Benzenes