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Broxuridine

Broxuridine
Broxuridine structure
CAS No.
59-14-3
Chemical Name:
Broxuridine
Synonyms
BDU;BUDR;5-bdu;BRUDR;BR-DU;5-BRDU;5-budr;radibud;NSC-3829;5-BrdU5G
CBNumber:
CB2775230
Molecular Formula:
C9H11BrN2O5
Formula Weight:
307.1
MOL File:
59-14-3.mol

Broxuridine Properties

Melting point:
191-194 °C (dec.)(lit.)
alpha 
31 º (c=1, 0.1N NaOH)
Density 
1.8573 (rough estimate)
refractive index 
22 ° (C=1, H2O)
storage temp. 
2-8°C
solubility 
NH4OH: 0.1 M at 20 °C, clear, colorless
form 
Crystals or Crystalline Powder
color 
White to yellow
Water Solubility 
1-5 g/100 mL at 22 ºC
Merck 
14,1452
BRN 
30395
Stability:
Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
InChIKey
XMJRLEURHMTTRX-UHFFFAOYSA-N
CAS DataBase Reference
59-14-3(CAS DataBase Reference)
EPA Substance Registry System
Uridine, 5-bromo-2'-deoxy-(59-14-3)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,T
Risk Statements  68-36/37/38-63-46-24-61
Safety Statements  36/37/39-26-53-45-36
WGK Germany  2
RTECS  YU7350000
10-23
TSCA  Yes
HS Code  29349990
Hazardous Substances Data 59-14-3(Hazardous Substances Data)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Broxuridine price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B5002 5-Bromo-2′-deoxyuridine ≥99% (HPLC) 59-14-3 1g $111 2018-11-13 Buy
Sigma-Aldrich B5002 5-Bromo-2′-deoxyuridine ≥99% (HPLC) 59-14-3 5g $444 2018-11-13 Buy
TCI Chemical B1575 5-Bromo-2'-deoxyuridine >98.0%(HPLC)(T) 59-14-3 1g $69 2018-11-22 Buy
TCI Chemical B1575 5-Bromo-2'-deoxyuridine >98.0%(HPLC)(T) 59-14-3 5g $251 2018-11-22 Buy
Alfa Aesar H27260 5-Bromo-2'-deoxyuridine, 99% 59-14-3 5g $269 2018-11-13 Buy

Broxuridine Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

A Thymidine analogue used as a mutagen in genetic research. Selectively incorporated into cellular DNA during S-phase

Definition

ChEBI: A pyrimidine 2'-deoxyribonucleoside compound having 5-bromouracil as the nucleobase.

Uses

Research tool for measuring DNA synthesis.

General Description

White crystalline powder.

Air & Water Reactions

Water soluble.

Reactivity Profile

Broxuridine may be heat and light sensitive. .

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition Broxuridine emits very toxic fumes of bromide ion and NOx.

Fire Hazard

Flash point data for Broxuridine are not available; however, Broxuridine is probably combustible.

Safety Profile

Moderately toxic by subcutaneous, intravenous, intraperitoneal, and possibly other routes. Mildly toxic by ingestion. Experimental teratogenic and reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Brand NOx

Purification Methods

Recrystallise the uridine from EtOH or 96% EtOH. It has max 279 nm at pH 7.0, and 279 nm (log  3.95) at pH 1.9. Its RF values are 0.49, 0.46 and 0.53 in n-BuOH/AcOH/H2O (4:1:1), n-BuOH/EtOH/H2O (40:11:19) and i-PrOH-25% aqueous NH3-H2O (7:1:1), respectively. [Nature 209 230 1966, Pryst.s & Sorm Collect Czech Chem Comm 29 2956 1964, Beilstein 24 III/IV 1234.]

Broxuridine Preparation Products And Raw materials

Raw materials

Preparation Products


Broxuridine Suppliers

Global( 206)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Jinan Carbotang Biotech Co.,Ltd.
+86 15866703830
+86 0531-61324629 figo.gao@foxmail.com CHINA 263 58
Beijing Ribio Biotech Co.,Ltd
010-62664360
Sales@ribio.com.cn CHINA 114 58
Yunbio Tech Co.,Ltd.
18046518538
yunbiochem@126.com CHINA 251 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58
Nanjing Asian Chemical Co., Ltd. +86 (25) 82263158
+86 (25) 82263168 sales@asianchem.com.cn China 259 60
Wuhu Nuowei chemistry Co., Ltd. 0553-2911116 18055311600
0553-2911116 salesnuowei@163.com China 985 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76

View Lastest Price from Broxuridine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-19 Broxuridine
59-14-3
US $1.00 / KG 1KG 95% 500KG career henan chemical co

Broxuridine Spectrum


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