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Methanesulfonamide

CAS No.
3144-09-0
Chemical Name:
Methanesulfonamide
Synonyms
METHANSULFONAMIDE;Mesyl amide;METHYL SULFONAMIDE;METHANESULPHONAMIDE;Methanesulfonic amide;A sulfonaMide;METHYLSULFAMIDE;Methylsulfonamid;Methanesulfomide;Methansulfonamid
CBNumber:
CB2776813
Molecular Formula:
CH5NO2S
Molecular Weight:
95.12
MDL Number:
MFCD00007940
MOL File:
3144-09-0.mol
MSDS File:
SDS
Last updated:2024-04-22 18:05:02

Methanesulfonamide Properties

Melting point 85-89 °C(lit.)
Boiling point 208.2±23.0 °C(Predicted)
Density 1.229 (estimate)
refractive index 1.5130 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Slightly soluble in DMSO and methanol.
form Crystals, Powder or Flakes
pka 10.87±0.60(Predicted)
color White to yellow
BRN 1740835
InChIKey HNQIVZYLYMDVSB-UHFFFAOYSA-N
CAS DataBase Reference 3144-09-0(CAS DataBase Reference)
FDA UNII 98YB2P6NHR
NIST Chemistry Reference Methane sulfonamide(3144-09-0)
EPA Substance Registry System Methanesulfonamide (3144-09-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  3
TSCA  T
HazardClass  IRRITANT
HS Code  29350090
NFPA 704
1
2 0

Methanesulfonamide price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 64275 Methanesulfonamide ≥97.0% (CHN) 3144-09-0 10g $90.7 2024-03-01 Buy
Sigma-Aldrich 64275 Methanesulfonamide ≥97.0% (CHN) 3144-09-0 50g $146 2024-03-01 Buy
TCI Chemical M0915 Methanesulfonamide >98.0%(N) 3144-09-0 25g $41 2024-03-01 Buy
TCI Chemical M0915 Methanesulfonamide >98.0%(N) 3144-09-0 100g $123 2024-03-01 Buy
Alfa Aesar A10885 Methanesulfonamide, 98+% 3144-09-0 10g $30.65 2024-03-01 Buy
Product number Packaging Price Buy
64275 10g $90.7 Buy
64275 50g $146 Buy
M0915 25g $41 Buy
M0915 100g $123 Buy
A10885 10g $30.65 Buy

Methanesulfonamide Chemical Properties,Uses,Production

Chemical Properties

White to yellow crystals, powder or flakes

Uses

  • Methanesulfonamide is used in the synthesis of important organic reagents such as N-(2-methylthio-1-p-toluenesufonyl)methanesulfonamide and tert-butyl ((2-(trimethylsilyl)ethyl)sulfonyl)carbamate.
  • It can be used as a source of nitrogen in the conversion of carboxylic acids to corresponding nitriles.
  • It is widely used as a reagent in the synthesis of medicinally important compounds such as derivatives of indole-N-acetamide, methanesulfonamide pyrimidine-substituted 3,5-dihydroxy-6-heptenoates and repertaxin.

Uses

Methanesulfonamide will react with thionyl chloride, cyanates, carbon disulfide and ketones and aldehydes to prepare pharmaceuticals, brightening agent and other target molecules. It is also used in biological studies to predict binding affinity and binding mode of protein ligand complexes.

Synthesis Reference(s)

Journal of the American Chemical Society, 90, p. 4096, 1968 DOI: 10.1021/ja01017a032
The Journal of Organic Chemistry, 60, p. 7682, 1995 DOI: 10.1021/jo00128a048
Tetrahedron Letters, 35, p. 7201, 1994 DOI: 10.1016/0040-4039(94)85360-6

124-63-0
3144-09-0
Synthesis of Methanesulfonamide from Methanesulfonyl chloride
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View Lastest Price from Methanesulfonamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methanesulfonamide pictures 2024-04-22 Methanesulfonamide
3144-09-0
US $10.00 / kg 1kg 99.7% 200000kg Ouhuang Engineering Materials (Hubei) Co., Ltd
Methansulfonamid pictures 2024-01-18 Methansulfonamid
3144-09-0
US $6.00-0.60 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Methanesulfonamide pictures 2023-06-27 Methanesulfonamide
3144-09-0
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
  • Methanesulfonamide pictures
  • Methanesulfonamide
    3144-09-0
  • US $10.00 / kg
  • 99.7%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd
Methylsulfonamid METHYL SULFONYLAMINE LABOTEST-BB LT00153664 Methanesulfonamide, 98+% Methanesulphonamide,98+% Methanesulfonyl amide MethanesulfonaMid Methanesulfomide METHANESULPHANAMIDE METHANESULFONAMIDE METHYLSULFAMIDE Methanesulphonamide 97% A sulfonaMide MethanesulfonaMide, 98% 25GR Methanesulfonamide >=97.0% (CHN) Methanesulfonamide> Methanesulfonamide, 98%, for synthesis Methansulfonamid METHYL SULFONAMIDE Mesyl amide METHANSULFONAMIDE METHANESULPHONAMIDE Methanesulfonic amide Methanesulfonamide (6CI, 7CI, 8CI, 9CI, ACI) Selexipag Impurity 21 2-Phenoxy-phenyl methane sulphonamide 3144-09-0 3I44-09-0 CH5NO2S CH3SO2NH2 CH5O2NS Building Blocks Organic Building Blocks Sulfur Compounds Sulfonamides/Sulfinamides Pharmaceutical Intermediates