ChemicalBook >> CAS DataBase List >>Desonide
Desonide
- CAS No.
- 638-94-8
- Chemical Name:
- Desonide
- Synonyms
- Tridesilon;PREDNACINOLONE;d-2083;Topifug;The Ned;DESONIDE;Locapred;Desonade;steroderm;Be Consolide
- CBNumber:
- CB2783466
- Molecular Formula:
- C24H32O6
- Molecular Weight:
- 416.51
- MDL Number:
- MFCD00866151
- MOL File:
- 638-94-8.mol
Last updated:2023-11-06 16:47:05
| Melting point | 272-274?C |
|---|---|
| Boiling point | 580.1±50.0 °C(Predicted) |
| Density | 1.30±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMF (Slightly, Sonicated), DMSO (Sparingly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 12.87±0.10(Predicted) |
| color | White to Off-White |
| CAS DataBase Reference | 638-94-8(CAS DataBase Reference) |
| FDA UNII | J280872D1O |
| ATC code | D07AB08,S01BA11 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H372-H312 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P260-P264-P270-P314-P501 | |||||||||
| HS Code | 2937290000 | |||||||||
| Toxicity | LD50 in rats (mg/kg): 93 s.c. (Phillips) | |||||||||
| NFPA 704 |
|
Desonide price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS021596 | Desonide | 638-94-8 | 50MG | $37.8 | 2022-05-15 | Buy |
| TCI Chemical | D5578 | Desonide | 638-94-8 | 250MG | $27 | 2024-03-01 | Buy |
| TCI Chemical | D5578 | Desonide | 638-94-8 | 1G | $75 | 2024-03-01 | Buy |
| Cayman Chemical | 21368 | Desonide ≥98% | 638-94-8 | 50mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 21368 | Desonide ≥98% | 638-94-8 | 100mg | $176 | 2024-03-01 | Buy |
Desonide Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Originator
Tridesilon,Dome,US,1972
Uses
antifungal
Uses
Desonide(Budesonide EP Impurity F) is an impurity of Budesonide (B689490), an anti-inflammatory.
Uses
Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).
Indications
Desonide (DesOwen, Tridesilon) is a synthetic corticosteroid.
Definition
ChEBI: Triamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders.
Manufacturing Process
Preparation of 11β,21-Dihydroxy-16α,17α-Isopropylidenedioxy-1,4- Pregnadiene-3,20-Dione: A solution of 11β,16α,17α,21-tetrahydroxy-1,4- pregnadiene-3,20-dione (40 mg) in acetone (10 ml) containing hydrochloric acid (three drops; d 1.19) is boiled 3n the steam bath for two minutes and then allowed to stand for eighteen hours at room temperature. The reaction mixture is diluted with water (50 ml) and extracted with chloroform (3x25 ml), the combined extracts then being washed with water (30 ml) and dried over anhydrous sodium sulfate. The residue obtained by removal of solvent crystallized from ethyl acetate-petroleum ether as small plates (25 mg), melting point 257°-260°C.
brand name
Desowen (Galderma); Tridesilon (Perrigo).
Therapeutic Function
Antiinflammatory
Desonide Preparation Products And Raw materials
Global( 455)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Joyochem Co.,Ltd | +86-0531-82687558 +8613290333633 | sales@joyochem.com | China | 42 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1011 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
View Lastest Price from Desonide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-15 | Desonide
638-94-8
|
US $1.00 / mg | 100mg | 0.99 | 5ton/month | ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD | |
 |
2024-01-08 | Desonide
638-94-8
|
US $9.00 / KG | 1KG | 99% | 50000tons | Wuhan Boyuan Import & Export Co., LTD | |
 |
2024-01-02 | Desonide
638-94-8
|
US $70.00-700.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd |
638-94-8(Desonide)Related Search:
(r)-budesonide
Ciclesonide
11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
14,15-Dehydro Budesonide
9α-BroMobudesonide
16α,17-[(1RS)-Butylidenebis(oxy)]-11β-hydroxy-17-(hydroxyMethyl)-D-hoMoandrosta-1,4-diene-3,17a-dione
(Mixture of DiastereoMers)
LY2228820
Meprednisone
Dienogestrel
Clopidogrel Bisulfate
1of4
DESONIDE
1,4-PREGNADIEN-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE
(11b,16a)-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione
16-alpha-hydroxyprednisole-16,17-acetonide
17-acetonide,16-alpha-hydroxy-prednisolone-1
d-2083
steroderm
Desonidemicro
(11β,16α)-11,21-Dihydroxy-16,17-[(1-Methylethylidene)bis(oxy)]pregna
-1,4-diene-3,20-dione
16α-Hydroxyprednisolone Acetonide
(11,16a)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
16a-Hydroxyprednisolone Acetonide
Locapred
Topifug
Be Consolide
16a-Hydroxyprednisole-16,17-acetonide
Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11b,16a)-
Desonide (250 mg)
Desonide, >=99%
Budesonide EP Impurity F(Desonide)
16α,17-[1-methylethylidenebis(oxy)]-11β,21-dihydroxypregna-1,4-diene-3,20-dione
Budesonide impurity F
Budesonide Impurity F (Desonide)
DesonideBiocar
Budesonide Impurity 6(Budesonide EP Impurity F)
Budesonide iMpurit F
Budesonide EP Impurity F
11beta,21-Dihydroxy-16alpha,17alpha-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-
Desonide Solution in Acetonitrile, 100μg/mL
(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
(11beta,16alpha)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
Budesonide Acetonide
Desonide USP/EP/BP
DesonideQ: What is
Desonide Q: What is the CAS Number of
Desonide Q: What is the storage condition of
Desonide
16a,17-[1-Methylethylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione
Desonide (1173304)
PREDNACINOLONE
Tridesilon
The Ned
-Amino-2-methyl-283H-tetrazole
Desonide (Budesonide acetonide)
API Steriods Desonide Powder Dosage Usage Effect and Benefit
16α,17-[1-methylethylidenebis(oxy)]-11β,21-dihydroxypregna-1,4-diene-3,20-dione
Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-
Desonide (Budesonide EP Impurity F)
Desonide EP Impurity-E
1, 4-PREGNADIEN-11β, 16α, 17, 21-TETROL-3, 20-DIONE 16, 17-ACETONIDE
Desonide/(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
Desonade
(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-Hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
638-94-8
C24H32O6
SPORANOX
Hormone Drugs
Chiral Reagents
Intermediates & Fine Chemicals
Pharmaceuticals