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5-Fluoropyrimidine-4,6-diol

5-Fluoropyrimidine-4,6-diol Structure
5-Fluoropyrimidine-4,6-diol structure
CAS No.
106615-61-6
Chemical Name:
5-Fluoropyrimidine-4,6-diol
Synonyms
5-FLUORO-PYRIMIDINE-4,6-DIOL;4,6-Dihydroxy-5-fluoropyrimidine;5-Fluoro-4,6-dihydroxypyrimidine;5-Fluoro-6-hydroxy-4(3H)-pyrimidinone;5-fluoro-4-hydroxy-1H-pyrimidin-6-one;5-fluoro-6-hydroxypyriMidin-4(3H)-one;4(3H)-PyriMidinone, 5-fluoro-6-hydroxy-;4(1H)-Pyrimidinone, 5-fluoro-6-hydroxy- (9CI);5-fluoro-6-hydroxy-3,4-dihydropyrimidin-4-one;5-FLUORO-PYRIMIDINE-4,6-DIOL ISO 9001：2015 REACH
CBNumber:
CB2793070
Molecular Formula:
C4H3FN2O2
Molecular Weight:
130.08
MDL Number:
MFCD09033260
MOL File:
106615-61-6.mol
MSDS File:
SDS
Request For Quotation

5-Fluoropyrimidine-4,6-diol Properties

Density 1.73±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 3.42±0.10(Predicted)

SAFETY

Risk and Safety Statements

HazardClass  IRRITANT
HS Code  29335990

5-Fluoropyrimidine-4,6-diol price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B435445 5-Fluoropyrimidine-4,6-diol 106615-61-6 250mg $55 2021-12-16 Buy
AK Scientific X8810 5-Fluoropyrimidine-4,6-diol 106615-61-6 1g $111 2021-12-16 Buy
Matrix Scientific 059839 5-Fluoropyrimidine-4,6-diol >96% 106615-61-6 1g $124 2021-12-16 Buy
ChemScene CS-W000796 5-fluoropyrimidine-4,6-diol 106615-61-6 5g $155 2021-12-16 Buy
Matrix Scientific 059839 5-Fluoropyrimidine-4,6-diol >96% 106615-61-6 500mg $163 2021-12-16 Buy
Product number Packaging Price Buy
B435445 250mg $55 Buy
X8810 1g $111 Buy
059839 1g $124 Buy
CS-W000796 5g $155 Buy
059839 500mg $163 Buy

5-Fluoropyrimidine-4,6-diol Chemical Properties,Uses,Production

Uses

5-Fluoropyrimidine-4,6-diol is used in preparation of Phenylpyrimidine derivatives and analogs for use as Kynurenine-3-monooxygenase inhibitors.

Preparation

synthesis of 5-Fluoro-4,6-dihydroxypyrimidine: Formamidine acetate (2.06 g, 20 mmol) was added to the solution of sodium (1.38 g, 60 mmol) in anhydrous ethanol (40 mL) and the mixture was heated to reflux. Diethyl 2-fluoromalonate (3.20 g, 18 mmol) was added dropwise over 20 minutes and the mixture was heated at reflux for 6 h. After cooling to room temperature, the solution was evaporated to dryness, the residue was dissolved in water (20 mL), acidified with HCl (5 mL), the precipitate was filtered, washed with water (5 mL), ethanol (2 × 5 mL) and diethyl ether (2 × 5 mL). After drying in vacuo, 5-fluoro-4,6-dihydroxypyrimidine (1.50 g, 64%) was obtained as a brown powder.
m.p.: >300 °C; ([M + H]+ , 131.0244, C4H4FN2O2 requires: [M]+ , 131.0257); IR (neat, cm-1 ) 3053, 2639, 1633, 1547, 1388, 1213; δH (DMSO d6, 400 MHz) 7.90 (1H, s, C-H), 12.38 (2H, bs, OH); δF (DMSO d6, 376 MHz): -178.06 (s); δC (DMSO d6, 100 MHz) 132.79 (d, 1 JCF 235.6, C-F), 144.46 (d, 4 JCF 7.7, C-H), 155.83 (d, 2 JCF 15.0, C-OH); m/z (ASAP) 131 (100%, [M + H]+ ).21a

5-Fluoropyrimidine-4,6-diol Preparation Products And Raw materials

Raw materials

Preparation Products

4,6-Dichloro-5-fluoropyrimidine

5-Fluoropyrimidine-4,6-diol Suppliers

Global( 133)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 6992 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21149 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Accela ChemBio Inc. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58

View Lastest Price from 5-Fluoropyrimidine-4,6-diol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-FLUORO-PYRIMIDINE-4,6-DIOL pictures 2021-12-10 5-FLUORO-PYRIMIDINE-4,6-DIOL
106615-61-6
 US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
5-FLUORO-PYRIMIDINE-4,6-DIOL pictures 2019-07-06 5-FLUORO-PYRIMIDINE-4,6-DIOL
106615-61-6
 US $1.00 / KG 1KG 99% Customized Career Henan Chemical Co

106615-61-6(5-Fluoropyrimidine-4,6-diol)Related Search:

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2-[(4,6-DIMETHOXY-5-FLUOROPYRIMIDIN-2-YL)OXY]BENZOIC ACID, METHYL ESTER 5-Fluoropyrimidine-4,6-diol FLUOXASTROBIN

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5-FLUORO-PYRIMIDINE-4,6-DIOL 4(1H)-Pyrimidinone, 5-fluoro-6-hydroxy- (9CI) 4,6-Dihydroxy-5-fluoropyrimidine 4(3H)-PyriMidinone, 5-fluoro-6-hydroxy- 5-fluoro-6-hydroxypyriMidin-4(3H)-one 5-fluoro-6-hydroxy-3,4-dihydropyrimidin-4-one 5-FLUORO-PYRIMIDINE-4,6-DIOL ISO 9001：2015 REACH 5-fluoro-4-hydroxy-1H-pyrimidin-6-one 5-Fluoro-4,6-dihydroxypyrimidine 5-Fluoro-6-hydroxy-4(3H)-pyrimidinone 106615-61-6 Fluorine series PYRIMIDINE