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METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE

CAS No.
550998-53-3
Chemical Name:
METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE
Synonyms
METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE;7-Bromo-benzo[b]thiophene-2-carboxylic acid methyl ester;Benzo[b]thiophene-2-carboxylic acid, 7-bromo-, methyl ester
CBNumber:
CB2798383
Molecular Formula:
C10H7BrO2S
Molecular Weight:
271.13
MDL Number:
MFCD09027095
MOL File:
Mol file
MSDS File:
SDS
Last updated:2025-07-24 18:13:53

METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE Properties

Melting point 99-102°C
storage temp. 2-8°C(protect from light)
form solid
color Off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P310+P330-P405
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2934999090

METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 047092 Methyl 7-bromo-1-benzothiophene-2-carboxylate >95% 550998-53-3 500mg $109 2021-12-16 Buy
Matrix Scientific 047092 Methyl 7-bromo-1-benzothiophene-2-carboxylate >95% 550998-53-3 1g $145 2021-12-16 Buy
AK Scientific 8024AB Methyl7-bromobenzo[b]thiophene-2-carboxylate 550998-53-3 250mg $154 2021-12-16 Buy
AK Scientific 8024AB Methyl7-bromobenzo[b]thiophene-2-carboxylate 550998-53-3 1g $176 2021-12-16 Buy
SynQuest Laboratories 6H23-9-05 Methyl 7-bromobenzo[b]thiophene-2-carboxylate 550998-53-3 5G $340 2021-12-16 Buy
Product number Packaging Price Buy
047092 500mg $109 Buy
047092 1g $145 Buy
8024AB 250mg $154 Buy
8024AB 1g $176 Buy
6H23-9-05 5G $340 Buy

METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE Chemical Properties,Uses,Production

Synthesis

2-BROMO-3-FLUOROBENZALDEHYDE

149947-15-9

Methyl thioglycolate

2365-48-2

METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE

550998-53-3

GENERAL METHOD: Under stirring conditions, 3-bromo-2-fluorobenzaldehyde (9.90 mmol) was dissolved in DMF (20 mL) and methyl mercaptoacetate (10.9 mmol) and potassium carbonate (39.6 mmol) were added sequentially. The reaction mixture was stirred continuously at 60 °C for 15 hours. After completion of the reaction, the DMF solvent was removed by distillation under reduced pressure. Water (50 mL) was added to the residue, which was subsequently extracted with ethyl acetate (2 x 40 mL). The organic phases were combined, dried with anhydrous sodium sulfate, filtered, and concentrated under reduced pressure to remove the solvent to afford the target product, methyl 7-bromobenzo[b]thiophene-2-carboxylate.

References

[1] European Journal of Medicinal Chemistry, 2017, vol. 125, p. 538 - 550
[2] Patent: KR2015/117318, 2015, A. Location in patent: Paragraph 0181; 0187; 0188; 0189

1072-85-1
550998-53-3
Synthesis of METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE from 2-Bromofluorobenzene

METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE Preparation Products And Raw materials

METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE Suppliers

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Hunan Jibang Biological Technology Co., LTD
+8613776644403 sales02@kingboomtech.com China 1804 58
Qingdao Dexin Chemical Co., Ltd
+86-15553333686 15553333686@qq.com China 3113 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 021-61259108 18621169109 market03@meryer.com China 40228 62
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35896 56
ShangHai AmK Pharmaceutical Technology Co., Ltd. 18019252918 sale@amkchem.com China 15297 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 18626450290 yftan@aikonchem.com China 16679 50
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 12346 58
Shanghai Kahn Pharmaceutical Co., Ltd. 021-34979681; 17701870669 41513101@qq.com China 1783 55

METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE Spectrum

METHYL 7-BROMO-1-BENZOTHIOPHENE-2-CARBOXYLATE 7-Bromo-benzo[b]thiophene-2-carboxylic acid methyl ester Benzo[b]thiophene-2-carboxylic acid, 7-bromo-, methyl ester 550998-53-3