Boc-aminoxy-PEG4-acid
- CAS No.
- 2062663-68-5
- Chemical Name:
- Boc-aminoxy-PEG4-acid
- Synonyms
- Boc-aminoxy-PEG4-acid;BocHNO-PEG4-CH2CH2COOH;N-Boc-Aminooxy-PEG4-acid;t-Boc-Aminooxy-PEG4-acid;Boc-aminoxy-PEG4-acid boc-;3,6,9,12,15-Pentaoxa-2-azaoctadecanedioic acid, 1-(1,1-dimethylethyl) ester;3-[2-[2-[2-[2-(tert-butoxycarbonylamino)oxyethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
- CBNumber:
- CB28054683
- Molecular Formula:
- C16H31NO9
- Molecular Weight:
- 381.42
- MDL Number:
- MFCD30536150
- MOL File:
- 2062663-68-5.mol
Boc-aminoxy-PEG4-acid Chemical Properties,Uses,Production
Description
t-Boc-Aminooxy-PEG4-acid contains a Boc-protected aminooxy group and a terminal carboxylic acid. The terminal carboxylic acid (CO2H) is reactive with primary amine groups in the presence of EDC, to form a amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc-protected amine can be deprotected under mild acidic conditions.
Uses
Boc-aminoxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Boc-aminoxy-PEG4-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Boc-aminoxy-PEG4-acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32376 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38838 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28789 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4822 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54999 | 58 |
| Zhengzhou Convergence Chemical Co. LTD | 0371-0371-53736046 13393710386 | 2853979814@qq.com | China | 10001 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 3001317055@qq.com | China | 9528 | 58 |
View Lastest Price from Boc-aminoxy-PEG4-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-21 | Boc-aminoxy-PEG4-acid
2062663-68-5
|
US $55.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | t-Boc-Aminooxy-PEG4-acid
2062663-68-5
|
US $0.00 / mg | 500mg | >98.00% | 500mg | Xian confluore Biological Technology Co., Ltd. |
-
- Boc-aminoxy-PEG4-acid
2062663-68-5
- US $55.00 / mg
- TargetMol Chemicals Inc.
-
- t-Boc-Aminooxy-PEG4-acid
2062663-68-5
- US $0.00 / mg
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
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