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Temocapril hydrochloride

Temocapril hydrochloride Structure
Temocapril hydrochloride structure
CAS No.
110221-44-8
Chemical Name:
Temocapril hydrochloride
Synonyms
CS-622;Acecol;CS-622 HCl;TemocarpileHCL;Temocapril Hcl;Carbovir Impurity 4;Temocarpilhydrochloride;TEMOCAPRIL HYDROCHLORIDE;CS-622 HCl|Temocapril HCl;Temocapril hydrochloride, >=99%
CBNumber:
CB2841030
Molecular Formula:
C23H28N2O5S2.ClH
Molecular Weight:
513.076
MDL Number:
MFCD00933433
MOL File:
110221-44-8.mol
Last updated:2023-05-18 11:30:59
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Temocapril hydrochloride Properties

Melting point 196-2000C (dec)
alpha 25D +47.7° (c = 1 in DMF)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
CAS DataBase Reference 110221-44-8(CAS DataBase Reference)
FDA UNII 8G820I95VP

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
Toxicity LD50 in mice, rats, dogs (mg/kg): >5000, >5000, >800 orally (Koike)

Temocapril hydrochloride price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18241 Temocapril (hydrochloride) ≥98% 110221-44-8 5mg $32 2024-03-01 Buy
Cayman Chemical 18241 Temocapril (hydrochloride) ≥98% 110221-44-8 10mg $61 2024-03-01 Buy
Cayman Chemical 18241 Temocapril (hydrochloride) ≥98% 110221-44-8 25mg $116 2024-03-01 Buy
Cayman Chemical 18241 Temocapril (hydrochloride) ≥98% 110221-44-8 50mg $214 2024-03-01 Buy
TRC T017301 TemocaprilHydrochloride 110221-44-8 5mg $60 2021-12-16 Buy
Product number Packaging Price Buy
18241 5mg $32 Buy
18241 10mg $61 Buy
18241 25mg $116 Buy
18241 50mg $214 Buy
T017301 5mg $60 Buy

Temocapril hydrochloride Chemical Properties,Uses,Production

Description

Temocapril is a novel ACE inhibitor marketed in Japan for the treatment of hypertension. Temocapril is three times more potent than enalapril by oral administration, and has a long duration of action. It is characterized by a rapid onset of action resulting from a fast conversion of temocapril to the active metabolite diacid. Unlike most ACE inhibitors which are excreted mainly through the kidneys, temocapril is excreted predominantly through the biliary route indicating that temocapril is especially useful for treating hypertensive patients with renal dysfunction. The potential usefulness of temocapril in the treatment of congestive heart failure has been reported.

Chemical Properties

White To Off-White Solid

Originator

Sankyo (Japan)

Uses

Angiotensin-converting enzyme (ACE) inhibitor. Hydrolyzed in vivo to the active diacid metabolite.

Uses

angiotensin-converting enzyme inhibitor (ACE-I)

Definition

ChEBI: Temocapril hydrochloride is a dipeptide.

brand name

Acecol

Temocapril hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Temocapril hydrochloride Suppliers

Global( 178)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Xiamen AmoyChem Co., Ltd 		+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17367 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10326 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Xiamen AmoyChem Co., Ltd 		58
BOC Sciences 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
SIMAGCHEM CORP 		58
Hubei Ipure Biology Co., Ltd 		58

View Lastest Price from Temocapril hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Temocapril hydrochloride pictures 2022-12-27 Temocapril hydrochloride
110221-44-8
 US $25.00-18.00 / kg 1kg 99% 1000kg Hebei Duling International Trade Co. LTD
Temocapril hydrochloride pictures 2021-07-13 Temocapril hydrochloride
110221-44-8
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
Temocapril hydrochloride pictures 2021-07-10 Temocapril hydrochloride
110221-44-8
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

Temocapril hydrochloride Spectrum

Temocapril hydrochloride(110221-44-8)1HNMR

110221-44-8(Temocapril hydrochloride)Related Search:

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Cetirizine dihydrochloride Topotecan hydrochloride Pyridine hydrochloride 1,1'-Carbonyldiimidazole Temocaprilat
ALTRENOGEST 2-[(2S)-6-[[(1S)-1-Ethoxycarbonyl-3-phenyl-propyl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid L-Homophenylalanine ethyl ester hydrochloride

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TEMOCAPRIL HYDROCHLORIDE Acecol CS-622 1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, (2S,6R)- (9CI) 1,4-Thiazepine-4(5H)-acetic acid, 6-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, [2S-[2a,6b(R*)]]- Temocapril Hcl TemocarpileHCL Temocarpilhydrochloride (2S,6R)-6-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic Acid Hydrochloride (+)-[(2S,6R)-6-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-5-oxo-2-(2-thienyl)perhydro-1,4-thiazepin-4-yl]acetic acid hydrochloride (2S,6R)-6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic acid,hydrochloride (1:1) CS-622 HCl Temocapril hydrochloride, >=99% 2-[(2S,6R)-6-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-5-oxo-2-(2-thienyl)-2,5,6,7-tetrahydro-1,4-thiazepine-4(3H)-yl]acetic acid·hydrochloride 1,4-Thiazepine-4(5H)-aceticacid,6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-,hydrochloride (1:1), (2S,6R)- Temocapril HCl and intermediates 2-[6-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid hydrochloride Temocapril hydrochloride USP/EP/BP TIANFU-CHEM - Temocapril hydrochloride 2-((2S,6R)-6-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl)acetic acid hydrochloride Carbovir Impurity 4 CS-622 HCl|Temocapril HCl 110221-44-8 10221-44-8 110221-48-8 C23H28N2O5S2HCl C23H28N2O5S2xHCl C23H29ClN2O5S2 Intermediates & Fine Chemicals Pharmaceuticals Inhibitors