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L-Homoserine

L-Homoserine structure

CAS No.: 672-15-1

Chemical Name:: L-Homoserine

Synonyms: HOMOSERINE;HSE;(S)-2-AMINO-4-HYDROXYBUTANOIC ACID;H-HOMOSER-OH;H-HSE-OH;H-HOSER-OH;H-HOMOSERINE;(2S)-2-Amino-4-hydroxybutanoic acid;RODH;SDR9C6

CBNumber:: CB2854094

Molecular Formula:: C4H9NO3

Molecular Weight:: 119.12

MDL Number:: MFCD00063090

MOL File:: 672-15-1.mol

MSDS File:: SDS

Last updated:2023-10-13 18:16:27

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L-Homoserine Properties

Melting point	203 °C (dec.)(lit.)
Boiling point	222.38°C (rough estimate)
alpha	-8.5 º (c=2, H2O 22 ºC)
Density	1.3126 (rough estimate)
refractive index	1.4183 (estimate)
storage temp.	Store below +30°C.
solubility	1100g/l
form	Crystalline Powder
pka	2.71(at 25℃)
color	White to light yellow
Water Solubility	1100 g/L (30 ºC)
Merck	14,4739
BRN	1721681
InChIKey	UKAUYVFTDYCKQA-VKHMYHEASA-N
LogP	-1.289 (est)
CAS DataBase Reference	672-15-1(CAS DataBase Reference)
FDA UNII	6KA95X0IVO

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P271-P280

Risk Statements

36/37/38

Safety Statements

24/25-44-35-26-28-7-4-3/9

WGK Germany

HS Code

29225000

NFPA 704

	0
0		0

L-Homoserine price More Price(58)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H6515	L-Homoserine	672-15-1	1g	$365	2024-03-01	Buy
Sigma-Aldrich	H6515	L-Homoserine	672-15-1	5g	$1720	2024-03-01	Buy
Sigma-Aldrich	8.14359	L-(-)-Homoserine for synthesis	672-15-1	1g	$147	2024-03-01	Buy
TCI Chemical	H1030	L-Homoserine >98.0%(T)	672-15-1	1g	$62	2024-03-01	Buy
TCI Chemical	H1030	L-Homoserine >98.0%(T)	672-15-1	5g	$204	2024-03-01	Buy

Product number	Packaging	Price	Buy
H6515	1g	$365	Buy
H6515	5g	$1720	Buy
8.14359	1g	$147	Buy
H1030	1g	$62	Buy
H1030	5g	$204	Buy

L-Homoserine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystalline powder

Uses

L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine. It is also used as an internal standard for neurotransmitter analysis and amino acids quantification.

Definition

ChEBI: L-homoserine is the L-enantiomer of homoserine. It has a role as a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite and an Escherichia coli metabolite. It is an enantiomer of a D-homoserine. It is a tautomer of a L-homoserine zwitterion.

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 3147, 1958 DOI: 10.1021/ja01545a057
The Journal of Organic Chemistry, 24, p. 1794, 1959 DOI: 10.1021/jo01093a610

General Description

L-Homoserine is a variant of serine with an additional carbon on its side chain.

Biochem/physiol Actions

L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.

Purification Methods

Likely impurities are N-chloroacetyl-L-homoserine, N-chloroacetyl-D-homoserine, L-homoserine, homoserine lactone, homoserine anhydride (formed in strong solutions of homoserine if slightly acidic). It cyclises to the lactone in strongly acidic solution. It crystallises from water by adding 9 volumes of EtOH. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2612-2616 1961, Beilstein 4 IV 3187.]

L-Homoserine synthesis

Synthesis of L-Homoserine from L-METHIONINE METHYLSULFONIUM IODIDE

L-Homoserine Preparation Products And Raw materials

Raw materials

Preparation Products

DL-Threonine L-Lysine hydrochloride N-Fmoc-L-homoserine O-ACETYL-L-HOMOSERINE HYDROCHLORIDE

L-Homoserine Suppliers

Global( 454)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alpha Biopharmaceuticals Co., Ltd	+86-411-39042497 +8613921981412	sales@alphabiopharm.com	China	886	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9353	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
AB PharmaTech,LLC	323-480-4688		United States	989	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58

Supplier	Advantage
Alpha Biopharmaceuticals Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
AB PharmaTech,LLC	55
career henan chemical co	58
Accela ChemBio Inc.	58
Hubei xin bonus chemical co. LTD	58

View Lastest Price from L-Homoserine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-02-21	L-Homoserine 672-15-1	US $0.00 / KG	1KG	98.0%	100 tons	Honest Joy Holdings Limited
2021-10-14	L-Homoserine 672-15-1	US $0.00 / KG	1KG	98.0%	5000kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2021-07-13	L-Homoserine 672-15-1	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

L-Homoserine
672-15-1
US $0.00 / KG
98.0%
Honest Joy Holdings Limited

L-Homoserine
672-15-1
US $0.00 / KG
98.0%
WUHAN FORTUNA CHEMICAL CO., LTD

L-Homoserine
672-15-1
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

L-Homoserine Spectrum

L-Homoserine(672-15-1)MS L-Homoserine(672-15-1)¹HNMR L-Homoserine(672-15-1)¹³CNMR L-Homoserine(672-15-1)IR1 L-Homoserine(672-15-1)IR2 L-Homoserine(672-15-1)Raman

672-15-1(L-Homoserine)Related Search:

trans-4-Hydroxy-L-proline methyl ester hydrochloride beta-Methyl L-aspartate hydrochloride H-ASP(OTBU)-OTBU HCL Dimethyl L-aspartate hydrochloride H-CIS-HYP-OME HCL

H-ASP(OET)-OET HCL L-Threonine DL-4-Amino-3-hydroxybutyric acid L(+)-allo-Threonine allo-DL-Threonine

DL-GAMMA-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE 2-Hydroxy-4-amino butanoic acid (S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid DL-Homoserine (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID

D(-)-allo-Threonine H-ASP-OBZL HCL H-ASP(OTBU)-OME HCL

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(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID (S)-2-AMINO-4-HYDROXYBUTYRIC ACID L-2-AMINO-4-HYDROXYBUTANOIC ACID L-2-AMINO-4-HYDROXYBUTYRIC ACID L-2-AMINO-4-HYDROXYBUTYRIC ACID HYDROCHLORIDE H-L-HSE-OH H-HOSER-OH HCL HOMOSERINE-L 2-AMINO-4-HYDROXYBUTYRIC ACID L-2-Amino-4-hydroxybutyricacid=H-Hser-OH (S)-Homeserine HOMOSERINE, (S)-2-AMINO-4-HYDROXYBUTYRIC ACID L-Homoserine, (S)-2-Amino-4-hydroxybutyric acid H-HOSER-OHCL L-Beta-Homo-Ser H-HoSer-OHCl;H-HoSer-OHCl L-Homoserine,97% (S)-2-Amino-4-hydroxybutyric acid Hse (S)-2-Amino-4-hydroxybutyric acid Hse H-HoSer-OH H-Hser-OH ,98% L-Homoserine NSC 206251 L-(-)-HOMOSERINE FOR SYNTHESIS L-HoMoserine, 95+% HSD17B6 RODH SDR9C6 L-Homoserine, >=98% L-Homoserine 98% L-Homoserine> L-Homoserine USP/EP/BP laevo-homoserine (2S)-2-azaniumyl-4-hydroxybutanoate L-Homoserine 672-15-1 H-HSE-OH H-HOSER-OH H-HOMOSER-OH H-HOMOSERINE HSE HOMOSERINE (S)-2-AMINO-4-HYDROXYBUTANOIC ACID (2S)-2-Amino-4-hydroxybutanoic acid L-Homoserine (9CI, ACI) (2S)-2-amino-4-hydroxybutanoic acid (homoserine) Lysine Impurity 12 (L-?Homoserine) Carisoprodol Impurity 3 (Carisoprodol EP Impurity C) 672-15-1 6-00-6 627-15-1 HOCH2CH2CHNH2COOH Amino Acid Library BioChemical Homo-Amino Acids Metabolomics Metabolic Libraries Peptide Synthesis Specialty Synthesis Unnatural Amino Acid Derivatives