ChemicalBook >> CAS DataBase List >>(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid

CAS No.
181289-33-8
Chemical Name:
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid
Synonyms
methylhexanoic acid;INTERMEDIATE OF PREGABALIN;(3R)-3-(2-AMino-2-oxoethyl)-5-Methylhexanoic Acid;(r)-(-)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid;PGL-S-CMH acid;Pregabalin Impurity 94;Pregabalin IMpurity III;Isobutyl-glutamonoamide;PREGABALINS INTERMEDIATES 03;Pregabalin Carbamoyl Impurity
CBNumber:
CB2854928
Molecular Formula:
C9H17NO3
Molecular Weight:
187.24
MDL Number:
MFCD09028111
MOL File:
181289-33-8.mol
Last updated:2024-04-24 17:21:45

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid Properties

Melting point 128-133°C
Boiling point 401.9±28.0 °C(Predicted)
Density 1.080±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 4.68±0.10(Predicted)
color White to Off-White
CAS DataBase Reference 181289-33-8(CAS DataBase Reference)
FDA UNII 77M6VOR9AZ

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H335-H315-H302
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C175955 (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoicacid 181289-33-8 5g $135 2021-12-16 Buy
Biosynth Carbosynth FA140304 (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid 181289-33-8 50g $150 2021-12-16 Buy
Biosynth Carbosynth FA140304 (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid 181289-33-8 25g $100 2021-12-16 Buy
Matrix Scientific 073067 R-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid 95+% 181289-33-8 25g $110 2021-12-16 Buy
American Custom Chemicals Corporation CCH0001191 (R)-(-)-3-(CARBAMOYMETHYL)-5-METHYLHEXANOIC ACID 95.00% 181289-33-8 1G $130.2 2021-12-16 Buy
Product number Packaging Price Buy
C175955 5g $135 Buy
FA140304 50g $150 Buy
FA140304 25g $100 Buy
073067 25g $110 Buy
CCH0001191 1G $130.2 Buy

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid Chemical Properties,Uses,Production

Uses

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid is a useful chemical intermediate for manufacturing of the anticonvulsant drug, Pregabalin1, 2.

Sources

  1. https://quod.lib.umich.edu/a/ark/5550190.0011.a22?rgn=main;view=fulltext
  2. https://www.researchgate.net/publication/269660675_Synthesis_and_characterization_of_impurities_of_an_anticonvulsant_drug_Pregabalin

Chemical Properties

White Solid

Uses

An Impurity of the anti-convulsant (S)-Pregabalin (P704790).

181289-15-6
181289-33-8
Synthesis of (R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid from 3-Carbamoymethyl-5-methylhexanoic acid

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid Preparation Products And Raw materials

Global( 363)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Chongqing Zhihe Biopharmaceutical Co., Ltd.
+86-18580541567 +86-17782035140 sales@zhswyy.com China 338 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 7786 58
Ouhuang Engineering Materials (Hubei) Co., Ltd
+8617702722807 admin@hbouhuang.com China 1696 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Nanjing Gold Pharmaceutical Technology Co. Ltd.
025-84209270 15906146951 CHINA 115 55
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58

View Lastest Price from (R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
R-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid pictures 2024-04-24 R-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid
181289-33-8
US $30.00 / kg 1kg 99.7% 200000kg Ouhuang Engineering Materials (Hubei) Co., Ltd
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid pictures 2024-04-24 (R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid
181289-33-8
US $0.00-0.00 / kg 0.10000000149011612kg 99 20tons Chongqing Zhihe Biopharmaceutical Co., Ltd.
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid pictures 2024-03-29 (R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid
181289-33-8
US $35.00-1.20 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
(r)-(-)-3-carbamoymethyl-5-methylhexanoic acid (R)-3-(2-AMINO-2-OXOETHYL)-5-METHYLHEXANOIC ACID:99+% 3-CarbaMoyl Mehyl-5-Methyl Hexanoic Acid Pregabalin IMpurity III Hexanoic acid,3-(2-aMino-2-oxoethyl)-5-Methyl-,(3R)- (R)-3-(2-AMino-2-oxoethyl)-5-Methylhexanoic acid (R)-3-(2-AMino-2-oxoethyl)-5-Methylhexanoic acid Pregabalin Carbamoyl Impurity (R)-(-)-3-carbamoy methyl)-5-methyl hexanoic acid(OR) (R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid 181289-33-8 181289-33-8 (R)-(-)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid (±)-3-Carbamoylmethyl)-5-methyl hexanoic acid (CMH Acid) Pregabalin Impurity III ((R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid) Isobutyl-glutamonoamide R-(-)-3-Carbamoylmethyl-5-hexanoic acid (R)-(-)-3-(CARBAMOYLMETHYL-5-METHYLMEXANOIC ACID Pregabalin Impurity III (3-Carbamoymethyl-5-Methylhexanoic Acid) (R)-3-(Carbamoylmethyl)-5-methylhex Pregabalin 3-Carbamoylmethyl Impurity PREGABALINS INTERMEDIATES 03 PGL-S-CMH acid 3-Carbamoylmethyl-5-methyl hexanoic acid (Recimic) (r)-(-)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid INTERMEDIATE OF PREGABALIN (3R)-3-(2-AMino-2-oxoethyl)-5-Methylhexanoic Acid methylhexanoic acid R-(-)-3-(Carbamoylmethyl)-5-methylhexanoicaci ?-(-)-3-(Carbamoyl methyl)-5-Methyl Haxanic Acid R (-}3-CARSAMOYLMETIHYL-5-METHYLHEXANOIC ACID (RCMH) 3-(2-Amino-2-oxoethyl)-5-methyl-(3S)-hexanoicacid 3-(Carbamoyl)-5-Methyl Hexanoic Acid R-(+)-3-(Carbamoylmethyl)-S- Methylhexanoic Acid R-3-(Carbamoylmethyl)-5-Methylhexanoic Acid (Rcmh) RCMH (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic Acid Pregablin Impurity (RCMH acid) Pregabalin Impurity 94 Isobutyl-glutamonoamide (R)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid 181289-33-8 181289-33-6 Aliphatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals intermidiate of Pregablin Starting Raw Materials & Intermediates 181289-33-8